Kim Shortall

Education

· 2018-Present: PhD candidate in the Department of Chemical Sciences, University of Limerick.

Research area: Production of ALDH from the thermophilic bacteria Thermus thermophilus for further immobilisation of this enzyme. In-situ immobilisation on MOF materials is of interest.

· 2014-2018: Bachelor of Science in Industrial Biochemistry (First class honours).

Final year project: “Sulfite detoxification mechanism of Thermus thermophilus HB8: Cloning of the sulfite-oxidoreductase”.

Current Research Project

OYSTER, Open characterisation and modelling environment to drive innovation in advanced nano-architectured and bio-inspired hard/soft interfaces, EU H2020, 2017-2021

Professional Experience

· Jan 2017- Aug 2017: TSMS downstream lab representative/TSMS lab analyst at Eli Lilly Kinsale Ltd. (Completed as part of the BSC)

Publication

1. Shortall, Kim, Edel Durack, Edmond Magner, and Tewfik Soulimane. "Study of ALDH from Thermus thermophilus–Expression, Purification and Characterisation of the Non-Substrate Specific, Thermophilic Enzyme Displaying Both Dehydrogenase and Esterase Activity." Cells 10, no. 12 (2021): 3535.

2. Shortall, K., Djeghader, A., Magner, E., & Soulimane, T. (2021). Insights into Aldehyde Dehydrogenase Enzymes: A Structural Perspective. Frontiers in Molecular Biosciences, 8, 410.

3. Otero, F., Shortall, K., Salaj-Kosla, U., Tofail, S. A., & Magner, E. (2021). Electrochemical biosensor for the detection of a sequence of the TP53 gene using a methylene blue labelled DNA probe. Electrochimica Acta, 138642.

4. Serleti, A., Xiao, X., Shortall, K., & Magner, E. (2021). Use of self-assembled monolayers for the sequential and independent immobilisation of enzymes.

5. Tocco, D., Carucci, C., Todde, D., Shortall, K., Otero, F., Sanjust, E., ... & Salis, A. (2021). Enzyme immobilization on metal organic frameworks: Laccase from Aspergillus sp. is better adapted to ZIF-zni rather than Fe-BTC. Colloids and Surfaces B: Biointerfaces, 208, 112147.