Publications

Papers

• Maalouly, E., Yamazaki, R., Nishio, S., Nørskov, M., Kamaga, K., Komai, S., Chiba, K., Atsumi, K., & *Akao, K.-I. (2024). The effect of conversation on altruism: A comparative study with different media and generations. PLOS ONE, 19(6), e0301769. https://doi.org/10.1371/journal.pone.0301769

• Maalouly, E., Yamazaki, R., Nishio, S., Nørskov, M., Kamaga, K., Komai, S., Chiba, K., Atsumi, K., & *Akao, K.-I. (2023). Assessing the effect of dialogue on altruism toward future generations: A preliminary study. Frontiers in Computer Science, 5, 28. https://doi.org/10.3389/FCOMP.2023.1129340

• Jin, M., Matsumoto, S., Ayaki, T., Yamakado, H., Taguchi, T., Togawa, N., Konno, A., Hirai, H., Nakajima, H., Komai, S., Ishida, R., Chiba, S., Takahashi, R., Takao, T., & *Hirotsune, S. (2022). DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers. Nature Communications, 13(1), 6880. https://doi.org/10.1038/s41467-022-34555-4

• Maruyama, A. T., & *Komai, S. (2018). Auditory-induced response in the primary sensory cortex of rodents. PLOS ONE, 13(12), e0209266. https://doi.org/10.1371/journal.pone.0209266

• *KOMAI, S. (2018). What Global Young Academy Is Working on SDGsグローバルヤングアカデミーにおけるSDGsへの取り組み. TRENDS IN THE SCIENCES. https://doi.org/10.5363/tits.23.1_68

• Arai, M. D. M. D., Zhan, B. B., Maruyama, A., Matsui-Harada, A., Horinouchi, K., & *Komai, S. (2017). Enriched environment and Mash1 transfection affect neural stem cell differentiation after transplantation into the adult somatosensory cortex. Journal of the Neurological Sciences, 373. https://doi.org/10.1016/j.jns.2016.12.013

• Building Bridges through Science, 96 Neuron (2017). https://doi.org/10.1016/j.neuron.2017.09.028

• JURI, Y., KOMAI, S., OKONOGI, A., OHOKA, M., TATSUMI, K., SHINTAKU, H., YOKOKAWA, R., & *KOTERA, H. (2017). J161043 Micro-Device for Light-Induced Stimulation on Cells via Light-Responsive Proteins. The Proceedings of Mechanical Engineering Congress, Japan. https://doi.org/10.1299/jsmemecj.2012._j161043-1

• Yokota, S., Suzuki, Y., Hamami, K., Harada, A., & *Komai, S. (2017). Sex differences in avoidance behavior after perceiving potential risk in mice. Behavioral and Brain Functions, 13(1). https://doi.org/10.1186/s12993-017-0126-3

• *Neergheen-Bhujun, V., Awan, A. T., Baran, Y., Bunnefeld, N., Chan, K., dela Cruz, T. E., Egamberdieva, D., Elsässer, S., Johnson, M. V., Komai, S., Konevega, A. L., Malone, J. H., Mason, P., Nguon, R., Piper, R., Shrestha, U. B., Pešić, M., & Kagansky, A. (2017). Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action. Journal of Global Health, 7(2). https://doi.org/10.7189/jogh.07.020304

• UENO, H., KOMAI, S., TERAO, K., TAKAO, H., SHIMOKAWA, F., KOTERA, H., & *SUZUKI, T. (2017). Development of Local Light Stimulation and Multi-point Measurement Device for Neural Network Analysis. The Proceedings of the Conference on Information, Intelligence and Precision Equipment : IIP. https://doi.org/10.1299/jsmeiip.2016.e-2-4

• Okuyama-Uchimura, F., & Komai, S. (2016). Mouse Ability to Perceive Subjective Contours. Perception, 45(3), 315–327. https://doi.org/10.1177/0301006615614440

• UENO, H., KOMAI, S., TERAO, K., TAKAO, H., SHIMOKAWA, F., KOTERA, H., & *SUZUKI, T. (2016). Development of a local light stimulation device integrated with micro electrode array. Mechanical Engineering Journal. https://doi.org/10.1299/mej.15-00570

• van Welie, I., Roth, A., Ho, S. S. N., Komai, S., & *Häusser, M. (2016). Conditional Spike Transmission Mediated by Electrical Coupling Ensures Millisecond Precision-Correlated Activity among Interneurons In Vivo. Neuron, 90(4), 810–823. https://doi.org/10.1016/j.neuron.2016.04.013

• Ahmad, A., & *Komai, S. (2016). Reducing the gap in neuroscience research between developed and developing countries. International Journal of Neuroscience, 126(3), 287–288. https://doi.org/10.3109/00207454.2015.1013194

• UENO, H., KOMAI, S., TERAO, K., TAKAO, H., SHIMOKAWA, F., KOTERA, H., & *SUZUKI, T. (2015). MoP-25 DEVELOPMENT OF A LOCAL LIGHT STIMULATION DEVICE INTEGRATED WITH MICRO ELECTRODE ARRAY. Proceedings of JSME-IIP/ASME-ISPS Joint Conference on Micromechatronics for Information and Precision Equipment : IIP/ISPS Joint MIPE, 2015(0). https://doi.org/10.1299/jsmemipe.2015._mop-25-1_

• Ahmad, A., Ashraf, S., & *Komai, S. (2015). Optogenetics applications for treating spinal cord injury. Asian Spine Journal, 9(2), 299–305. https://doi.org/10.4184/asj.2015.9.2.299

• Ahmad, A., Ashraf, S., Li, C., Ahmad, A., Ashraf, S., & *Komai, S. (2015). Are developing countries prepared to face Ebola-like outbreaks? Virologica Sinica, 234–237. https://doi.org/10.1007/s12250-015-3564-9

• Ahmad, A., & *Komai, S. (2015). Geriatrics and Gerontology: Neglected Areas of Research in Most Developing Countries. Journal of the American Geriatrics Society, 63(6), 1283–1284. https://doi.org/10.1111/jgs.13521

• Ahmad, A., & *Komai, S. (2015). Malnutrition and Neurologic Problems Among Children in the Developing World. Seminars in Pediatric Neurology. https://doi.org/10.1016/j.spen.2015.03.007

• Ahmad, A., & *Komai, S. (2015). Metastasis: Other Side of the Coin. Frontiers in Oncology, 5, 163. https://doi.org/10.3389/fonc.2015.00163

• Watanabe, J., Kubo, T., Komai, S., & *Kazushi, I. (2014). Automated Behavior Analysis of Mice Based on Novel Tracking and Non-Parametric Bayesian Clustering. The 24th Annual Conference of the Japanese Neural Network Society.

• Kongsmak, K., Pungpit, P., Kano, M. R., Komai, S., Piyawattanametha, W., & *Phanraksa, O. (2013). Perceptions of Research Excellence in Thailand and Japan. STI Policy Review.

• Arai, M., Yamamoto, T., & *Komai, S. (2011). Functional complementation of hippocampus with exogenous neural stem cells for cognitive recovery after application of kainic acid. Neuroscience Research. https://doi.org/10.1016/j.neures.2011.07.1264

• Okuyama, F., & *Komai, S. (2011). Basis of neural system of subjective contours in early visual cortex of mouse. Neuroscience Research. https://doi.org/10.1016/j.neures.2011.07.626

• *KOMAI, S. (2011). European Young Academy for European Science and Society. TRENDS IN THE SCIENCES. https://doi.org/10.5363/tits.15.9_106

• Arai, M. D., & *Komai, S. (2010). Functional differentiation of exogenous neural stem cells into excitatory and inhibitory neurons in adult mice cortex. Neuroscience Research. https://doi.org/10.1016/j.neures.2010.07.1589

• Arai, M., & *Komai, S. (2009). Analysis of formation mechanism for excitatory and inhibitory neural circuits. Neuroscience Research. https://doi.org/10.1016/j.neures.2009.09.794

• Ichida, M., Shiosaka, S., & *Komai, S. (2009). The expression of neuropsin mRNA is regulated by light and circadian rhythm. Neuroscience Research. https://doi.org/10.1016/j.neures.2009.09.1298

• Harada, A., Shiosaka, S., Ishikawa, Y., & *Komai, S. (2008). Acute stress increases neuropsin mRNA expression in the mouse hippocampus through the glucocorticoid pathway. Neuroscience Letters, 436(2), 273–277. https://doi.org/10.1016/j.neulet.2008.03.042

• *Komai, S. (2007). Dendritic excitability maturates somatosensory receptive field. Neuroscience Research. https://doi.org/10.1016/j.neures.2007.06.071

• Cetin, A., Komai, S., Eliava, M., Seeburg, P. H., & *Osten, P. (2007). Stereotaxic gene delivery in the rodent brain (Nature Protocol (2007) (3166-3173) 10.1038/nprot.2006.450). Nature Protocols, 1(6).

• Suto, F., Tsuboi, M., Kamiya, H., Mizuno, H., Kiyama, Y., Komai, S., Shimizu, M., Sanbo, M., Yagi, T., Hiromi, Y., Chédotal, A., Mitchell, K. J., Manabe, T., & *Fujisawa, H. (2007). Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A Control Lamina-Restricted Projection of Hippocampal Mossy Fibers. Neuron, 53(4), 535–547. https://doi.org/10.1016/j.neuron.2007.01.028

• Komai, S., Denk, W., Osten, P., Brecht, M., & *Margrie, T. W. (2006). Two-photon targeted patching (TPTP) in vivo. Nature Protocols, 1(2), 647–652. https://doi.org/10.1038/nprot.2006.100

• Komai, S., Licznerski, P., Cetin, A., Waters, J., Denk, W., Brecht, M., & *Osten, P. (2006). Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience-dependent development. Nature Neuroscience, 9(9), 1125–1133. https://doi.org/10.1038/nn1752

• Nakazawa, T., Komai, S., Watabe, A. M., Kiyama, Y., Fukaya, M., Arima-Yoshida, F., Horai, R., Sudo, K., Ebine, K., Delawary, M., Goto, J., Umemori, H., Tezuka, T., Iwakura, Y., Watanabe, M., Yamamoto, T., & *Manabe, T. (2006). NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. The EMBO Journal, 25(12), 2867–2877. https://doi.org/10.1038/sj.emboj.7601156

• Niisato, K., Fujikawa, A., Komai, S., Shintani, T., Watanabe, E., Sakaguchi, G., Katsuura, G., Manabe, T., & *Noda, M. (2005). Age-dependent enhancement of hippocampal long-term potentiation and impairment of spatial learning through the Rho-associated kinase pathway in protein tyrosine phosphatase receptor type Z-deficient mice. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 25(5), 1081–1088. https://doi.org/10.1523/JNEUROSCI.2565.04.2005

• Dittgen, T., Nimmerjahn, A., Komai, S., Licznerski, P., Waters, J., Margrie, T. W., Helmchen, F., Denk, W., Brecht, M., & *Osten, P. (2004). Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proceedings of the National Academy of Sciences of the United States of America, 101(52), 18206–18211. https://doi.org/10.1073/pnas.0407976101

• Komai, S., Momota, Y., Kato, K., Yoshida, S., & *Shiosaka, S. (2004). 1323 The physiological role of a serine protease, neuropsin, on the neural plasticity in hippocampus. Neuroscience Research. https://doi.org/10.1016/s0168-0102(97)90469-7

• Komai, S., Hirata, A., Yoshida, S., Kobayashi, M., Imamura, K., & *Shiosaka, S. (2003). The effects of neuropsin for the synaptic modification in neuropsin gene knockout mice. Neuroscience Research. https://doi.org/10.1016/s0168-0102(98)82456-5

• Komai, S., Yoshida, S., Matsuyama, T., & *Shiosaka, S. (2002). 609 The physiological roles of serine protease, neuropsin, in the hippocampus. Neuroscience Research. https://doi.org/10.1016/0168-0102(96)88761-x

• Nakazawa, T., Komai, S., Tezuka, T., Hisatsune, C., Umemori, H., Semba, K., Mishina, M., Manabe, T., & *Yamamoto, T. (2001). Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. The Journal of Biological Chemistry, 276(1), 693–699. https://doi.org/10.1074/jbc.M008085200

• Hashimoto, R., Nakamura, Y., Komai, S., Kashiwagi, Y., Tamura, K., Goto, T., Aimoto, S., Kaibuchi, K., Shiosaka, S., & *Takeda, M. (2000). Site-specific phosphorylation of neurofilament-L is mediated by calcium/calmodulin-dependent protein kinase II in the apical dendrites during long-term potentiation. J Neurochem, 75(1), 373–382. https://doi.org/10.1046/j.1471-4159.2000.0750373.x

• Hashimoto, R., Nakamura, Y., Komai, S., Kashiwagi, Y., Matsumoto, N., Shiosaka, S., & *Takeda, M. (2000). Phosphorylation of neurofilament-L during LTD. Neuroreport, 11(12), 2739–2742. https://doi.org/10.1097/00001756-200008210-00026

• Ugawa, S., Ueda, T., Takahashi, E., Hirabayashi, Y., Yoneda, T., Komai, S., & *Shimada, S. (2001). Cloning and functional expression of ASIC-β2, a splice variant of ASIC-β. NeuroReport. https://doi.org/10.1097/00001756-200109170-00022

• Komai, S., Matsuyama, T., Matsumoto, K., Kato, K., Kobayashi, M., Imamura, K., Yoshida, S., Ugawa, S., & *Shiosaka, S. (2000). Neuropsin regulates an early phase of Schaffer-collateral long-term potentiation in the murine hippocampus. European Journal of Neuroscience, 12(4), 1479–1486. https://doi.org/10.1046/j.1460-9568.2000.00035.x

• Kobayashi, M., Imamura, K., Sugai, T., Onoda, N., Yamamoto, M., Komai, S., & *Watanabe, Y. (2000). Selective suppression of horizontal propagation in rat visual cortex by norepinephrine. European Journal of Neuroscience, 12, 264–272. https://doi.org/10.1046/j.1460-9568.2000.00917.x

• Matsuyama, T., Matsushita, K., Akita, H., Ozaki, S., Sugita, M., Iso, H., Komai, S., Momota, Y., & *Shiosaka, S. (1997). 2235 Learning impairment in relation to the decrease in limbic-specific protease neuropsin. Neuroscience Research. https://doi.org/10.1016/s0168-0102(97)90720-3

Books

• “Deep History of Ourselves” written by Joseph LeDoux, translated into Japanese (2023) ジョセフ・ルドゥ著、駒井章治訳　「情動と理性のディープヒストリー」　化学同人（2023）

• Komai, S. "Microbehavioral Analysis for Understanding Animal Emotions," "Evolution of Emotions." Asakura Publishing Co., Ltd. (2015), 98-99. (Contributing Author)

• *Komai S., Activity Regulation in the Study of Neural Plasticity. “Optogenetics.” Springer Japan, Tokyo. （2015）291-304. (Contributing Author)

• Cetin A., and *Komai S., Behavioral control by light-exciting and silencing neuronal activity. “Methods in Neuroethological Research.” Springer Japan, Tokyo. 115-129.（2013）Contribution to Writing

• Komai, S., "Elucidation of Neural Plasticity Phenomena Accompanying Neural Activity," "Optogenetics (Light Genetics)." NTS Co., Ltd., Tokyo. (2013), 204-215. (Contributing Author)

• Komai, S., "Unlocking the Mysteries of the Brain 2," Edited by Kyoso Kubota, Asahi Shimbunsha, (1995), 215-222. (Contributing Author)

Invited talks：

• AI in Biomedical Innovation. Komai S, AI Summit, 13 December 2024 (Bangkok, Thailand).

• “Bioimaging for brain science” 「バイオイメージングの脳科学への応用」駒井章治 日本金属学会　日本金属学会　2018年秋期講演大会公募シンポジウムS5 バイオマテリアル科学におけるイメージング技術基調講演，2018年9月19日（仙台，招待講演）

• Using big data for behavioral analysis. Komai S, Idea Lab at IAP conference, 25, February, 2013 (Rio de Janeiro, 招待講演)

• Motion segmentation system to associate microscopic motion with its neuronal processing. Komai S, Ikeda K, Suzuki Y. Symposium on Neurosicence 2012, 19, September, 2012 (Nagoya, 招待講演)

• “Optogenetics for understanding of the sensory processing”「optogeneticsの感覚研究への応用」駒井章治 特定領域研究「細胞感覚」若手の会、2011年9月23日 (岡崎, 招待講演)

• Genetic regulation of a particular molecule in the brain. 「分子操作による神経活動制御技術」駒井章治 脳科学研究戦略推進プロジェクト課題C分科会、2009年12月1日 （京都、招待講演）