Turbulent wall model for hemolysis prediction

Researchers : Seunghun Lee

Motivation & Objectives

    - For medical devices with blood circulation such as ventricular assist device(VAD) and extra-corporeal membrane oxygenation(ECMO), hemolysis is a very important issue in terms of health safety

     : Hemolysis is a phenomenon that the membrane of a red blood cell (RBC) is damaged by stress and then the hemoglobin is released from RBC to the plasma.

    - In order to measure the level of hemolysis inside artificial medical devices, in-vitro experiments are possible but many iterations of such experiments to develop a medical device are often impractical.

     : A predictive capability of hemolysis using numerical simulation has a clear advantage by relieving these limitations.

    - The main objective is to develop a turbulent wall model for hemolysis to improve accuracy of hemolysis prediction.

Flow fields

    - BDI comparison between using wall model and conventional numerical discretization with 16G cannula

    - Comparison of the contour plots of power-law source term

      : Geometric shapes of commercial blood pumps (Capiox, BP-80) are tested    

< Geometry shape of Capiox >

< Power-law source term of Capiox >