Parkinson's is a degenerative disorder of the brain, specifically affecting the area of the brain called the Substantia Nigra which is located in the Basal Ganglia, a group of brain structure involved in motor control. Some of the common characteristics of Parkinson's include shuffling gait, resting tremor, reduced arm swing and cognitive changes. Parkinson's is the fastest growing neurological condition in the world.

Multiple Systems Atrophy (MSA) is a neurodegenerative condition that affects people's balance, movement and autonomic nervous system functions. People with MSA display signs of parkinsonism, cerebellar ataxia and autonomic dysfunction. There are two types, MSA-Parkinson's type which resembles idiopathic Parkinson's and MSA-Cerebellar type which combines features of cerebellar ataxia.

Progressive Supranuclear Palsy can cause problems with people's movement, balance, cognition, speech and swallowing. The condition worsens over time (progressive), causes weakness (palsy) due to damage above clusters of nerve cells that control eye movements (supranuclear).