Lynch Syndrome is a condition that increases the risk of having certain types of cancer. It is caused by a mutation in one of five different genes: MLH1, MSH2, MSH6, PMS2, EPCAM.

If you have Lynch Syndrome you are at greater risk of developing cancer because your cells' ability to repair DNA damage might be affected by the gene mutation. 

Lynch Syndrome is an autosomal dominant condition. This means that if you have it, each one of your children has a 50% chance of inheriting it from you. Lynch Syndrome is diagnosed through genetic testing

Click on the Lynch Syndrome genes below to learn about the risk associated with their mutation. 

(All the information provided in these pages draws on A beginner's guide to Lynch Syndrome, curated by the Royal Marsden NHS Foundation Trust. Pictures by Yifeng Zhang.)