研究室メンバーの主な研究業績
原著論文
Yoro, E. and Sakakibara, K. (2024) Sexual reproduction: Is the genetic pathway for female germ cell specification conserved in land plants? Current Biology 34(6), R241-R244.
Yoro, E., Koshimizu, S., Murata, T., Sakakibara, K., (2023) Protocol: an improved method for inducing sporophyte generation in the model moss Physcomitrium patens under nitrogen starvation. Plant Methods 19: 100. Link
Koshimizu, S., Minamino, N., Nishiyama, T., Yoro, E., Sato, M., Wakazaki, M., Toyooka, K., Ebine, K., Sakakibara, K., Ueda, T., Yano, K. (2022) “Phylogenetic distribution and expression pattern analyses identified a divergent basal body assembly protein involved in land plant spermatogenesis.” New Phytologist 236: 1182-1196. Link
Kodama, K., Rich, M. K., Yoda, A., Shimazaki, S., Xie, X., Akiyama, K., Mizuno, Y., Komatsu, A., Luo, Y., Suzuki, H., Kameoka, H., Libourel, C., Keller, J., Sakakibara, K., Nishiyama, T., Nakagawa, T., Mashiguchi, K., Uchida, K., Yoneyama, K., Tanaka, Y., Yamaguchi, S., Shimamura, M., Delaux, P.-M., Nomura, T., Kyozuka, J. (2022) "An ancestral function of strigolactones as symbiotic rhizosphere signals." Nature Commun 13: 3974. Link
Sadamitsu, A., Inoue, Y., Sakakibara, K., Tsubota, H., Yamaguchi, T., Deguchi, H., Nishiyama, T., Shimamura, M. (2021) "The complete plastid genome sequence of the enigmatic moss, Takakia lepidozioides (Takakiopsida, Bryophyta): evolutionary perspectives on the largest collection of genes in mosses and the intensive RNA editing." Plant Molecular Biology 107(1), 1-19. Link
Kawai, J., Kanazawa, M., Suzuki, R., Kikuchi, N., Hayakawa, Y., Sekimoto, H. (2022) “Highly efficient transformation of the model zygnematophycean alga Closterium peracerosum-strigosum-littorale complex by square-pulse electroporation.” New Phytologist 233(1), 569-578. Link
Frangedakis, E., Waller, M., Nishiyama, T., Tsukaya, H., Xu, X., Yue, Y., Tjahjadi, M., Gunadi, A., Eck, V.J., Li, F.W., Szövényi, P., Sakakibara, K. (2021) "An Agrobacterium-mediated stable transformation technique for the hornwort model Anthoceros agrestis" New Phytologist 232, 1488-1505 . Link
Li, F.W., Nishiyama, T., Waller, M., Frangedakis, E., Keller, J., Li, Z., Fernandez-Pozo, N., Barker, M., Bennett, T., Blázquez, M.A., Cheng, S., Cuming, A.C., de Vries, J., de Vries, S., Delaux, P.M., Diop, I.S., Harrison, C.J., Hauser, D., Hernández-García, J., Kirbis, A., Meeks, J.C., Monte, I., Mutte, S.K., Neubauer, A., Quandt, D., Robison, T., Shimamura, M., Rensing, S.A., Villarreal, J.C., Weijers, D., Wicke, S., Wong, G.K., Sakakibara, K., Szövényi, P. (2020) "Anthoceros genomes illuminate the origin of land plants and the unique biology of hornworts" Nature Plants 6, 259–272. Link
Yoro, E., Suzaki, T., Matsubayashi, Y., Kawaguchi, M. (2020) "CLE-HAR1 systemic signaling and NIN-mediated local signaling suppress the increased rhizobial infection in the daphne mutant in Lotus japonicus" Molecular Plant-Microbe Interactions 33: 320-327. Link
Yoro, E., Nishida, H., Ogawa-Ohnishi, M., Yoshida, C., Suzaki, T., Matsubayashi, Y., Kawaguchi, M. (2019) "PLENTY, a hydroxyproline O-arabinosyltransferase, negatively regulates root nodule symbiosis in Lotus japonicus" Journal of Experimental Botany 70: 507–517. Link 研究報告
Higo, A., Kawashima, T., Borg, M., Zhao, M., López-Vidriero, I., Sakayama, H., Montgomery, S. A., Sekimoto, H., Hackenberg, D., Shimamura, M., Nishiyama, T., Sakakibara, K., Togawa, T., Kunimoto, K., Suzuki, Y., Osakabe, A., Yamato, K. T., Ishizaki, K., Nishihama, R., Kohchi, T., Franco-Zorrilla, J. M., Twell, D., Berger, F., and Araki, T. (2018) "Transcription factor DUO1 generated by neo-functionalization is associated with evolution of sperm differentiation in plants" Nature Communications 9, Article number 5283. Link
Yip, H. K. Floyd, S. K. Sakakibara, K., Bowman, J. L. (2016) “Class III HD-Zip activity coordinates leaf development in Physcomitrella patens.” Developmental Biology 419: 184-197. Link
Furumizu, C., Alvarez, J. P., Sakakibara, K., Bowman J. L. (2015) "Antagonistic Roles for KNOX1 and KNOX2 Genes in Patterning the Land Plant Body Plan Following an Ancient Gene Duplication" PLOS Genetics 11: e1004980. Link
Sakakibara, K., Reisewitz, P., Aoyama, T., Friedrich, T., Ando, S., Sato, Y., Nishiyama, T., Tamada, Y., Hiwatashi, Y., Kurata, T., Ishikawa, M., Deguchi, H., Rensing, S. A., Werr, W., Murata, T., Hasebe, M., Laux, T. (2014) "WOX13-like genes are required for the initiation of apical stem cells from differentiated leaf cells in the moss Physcomitrella patens." Development 141:1660-1670. Link
Yoro, E., Suzaki, T., Toyokura, K., Miyazawa, H., Fukaki, H., Kawaguchi, M. (2014) "A positive regulator of nodule organogenesis, NODULE INCEPTION, acts as a negative regulator of rhizobial infection in Lotus japonicus." Plant Physiology 165: 747-758. Link 研究報告
Sakakibara, K.*, Ando, S., Yip, H. K., Tamada, Y., Hiwatashi, Y., Murata, T., Deguchi, H., Hasebe, M., Bowman, J. L.* (*Authors for correspondence) (2013) “KNOX2 genes regulate the haploid to diploid morphological transition in land plants.” Science 339: 1067-1070. Link
Zalewski, C. S., Floyd, S. K., Furumizu, C., Sakakibara, K., Stevenson, D. W., Bowman, J. L. (2013) “Phylogeny of Class IV HD-Zip genes and the evolution of epidermal complexity in land plants.” Mol. Biol. Evol. 30: 2347-65. Link
Kawai, J., Tanabe, Y., Soma, S., Ito, M. (2010) “Class 1 KNOX expression supports the Selaginella rhizophore concept.” Journal of Plant Biology 53: 268-274.
Kofuji, R., Yoshimura, T., Inoue, H., Sakakibara, K., Hiwatashi, Y., Kurata, T., Aoyama, T., Ueda, K., Hasebe, M.(2009) “Gametangia development in the moss Physcomitrella patens.” In Cove, D., Perroud, F., and Knight, C. eds. "The moss Physcomitrella". Black Well, Annual plant reviews 36: 167-181.
Sakakibara, K., Nishiyama, T., Deguchi, H., Hasebe, M. (2008) “Class 1 KNOX genes are not involved in shoot development in the moss Physcomitrella patens but do function in sporophyte development.” Evol. Dev. 10: 555-566. Link
Rensing, S. A., Lang, D., Zimmer, A., Terry, A., Salamov, A., Shapiro, H., Nishiyama, T., Perroud, P.-F., Lindquist, E., Kamisugi, Y., Tanahashi, T., Sakakibara, K. et al. (2008) “The genome of the moss Physcomitrella patens reveals evolutionary insights into the conquest of land by plants.” Science 319: 64-69. Link
Sano, R., Jua'rez, C. M., Hass, B., Sakakibara, K., Ito, M., Banks, J. A., Hasebe, M. (2005) “KNOX homeobox genes potentially have similar function in both diploid unicellular and multicellular meristems, but not in haploid meristems.” Evol. Dev. 7: 69-78. Link
Sakakibara, K., Nishiyama, T., Sumikawa, N., Kofuji, R., Murata, T., Hasebe, M. (2003) “Involvement of auxin and a homeodomain-leucine zipper I gene in rhizoid development of the moss Physcomitrella patens.” Development 130: 4835-4846. Link
Sakakibara, K., Nishiyama, T., Kato, M., Hasebe, M. (2001) “Isolation of Homeodomain-leucine zipper genes from the moss Physcomitrella patens and the evolution of Homeodomain-leucine zipper genes in land plants.” Mol. Biol. Evol. 18: 491-502. Link
Shindo, S., Sakakibara, K., Sano, R., Ueda, K., Hasebe, M. (2001) “Characterization of a FLORICAULA/LEAFY homologue of Gnetum parvifolium, and its implications for the evolution of reproductive organs in seed plants.” Int. J. Plant Sci. 162: 1199-1209. Link
Nishiyama, T., Hiwatashi, Y., Sakakibara, K., Kato, M., and Hasebe, M. (2000) “Tagged mutagenesis and gene-trap in the moss, Physcomitrella patens by shuttle mutagenesis.” DNA Research 7: 1-9. Link
総説
Frangedakis, E., Marron, A.O., Waller, M., Neubauer, A., Tse, S.W., Yue, Y., Ruaud, S., Waser, L., Sakakibara, K., Szövényi, P. (2023) "What can hornworts teach us?" Front Plant Sci. 2023 Mar 8;14:1108027. Link
Frangedakis, E., Shimamura, M., Villarreal, J.C., Li, F.W., Tomaselli, M., Waller, M., Sakakibara, K., Renzaglia, K.S., Szovenyi, P. (2020) ”The hornworts: morphology, evolution and development.” New Phytologist (in press). Link
Bowman, J. L. Sakakibara, K., Furumizu, C., Dierschke, T. (2016)“Evolution in the Cycles of Life.” Annual Review of Genetics 50: 6.1–6.22. Link
Sakakibara, K. (2016) "Technological Innovations Give Rise to a New Era of Plant Evolutionary" Developmental Biology. Advances in Botanical Research 78: 3-35.
*Suzaki, T., *Yoro, E., Kawaguchi M. (*co-first author) (2015) "Leguminous plants: inventors of root nodules to accommodate symbiotic bacteria." International Review of Cell and Molecular Biology 316: 111-158. *co-first Link
Bowman, J. L., Floyd, S. K., Sakakibara, K. (2007) “Green Genes―Comparative Genomics of the Green Branch of Life.” Cell 129: 229-34. Link
日本語著作等
西山智明・嶋村正樹・榊原恵子（2022）「ツノゴケ─ゲノム解読と形質転換技術が拓く植物進化研究の新機軸」遺伝2022年5月号 Link
嶋村正樹・西山智明・榊原恵子（2021）「陸上植物起源研究の最後のフロンティア、ツノゴケの生物学」Link
榊原恵子 (2017) 「植物の世代を切換えるスイッチ遺伝子」 生命誌ジャーナル 92号 Link
榊原恵子 (2016) 「植物の世代交代制御因子の発見」 慶応義塾大学出版 Link
石崎公庸・榊原恵子 (2016)「古い酒を新しい革袋に～preexisting gene regulatory network の転用による陸上植物のボディプラン革新」 BSJ-review 7B:47-54. Link
榊原恵子・古水千尋 (2016)「TALE型ホメオボックス遺伝子族の進化による陸上植物複相の複雑化」 BSJ-Review vol.7B: 66-77. Link
榊原恵子 (2014)「陸上植物の複相の巨大化と複雑化に貢献したホメオボックス遺伝子の重複と機能分化」細胞工学 Vol. 33 No. 8 Special Review: 872-877. Link
榊原恵子「陸上植物の世代交代の謎にせまる～遺伝子重複と機能分化による胞子体の劇的な形態進化～」 化学と生物 51 巻: 595-596. (2013).
榊原恵子 (2013)「KNOX2遺伝子は陸上植物の世代交代において複相から単相への移行を抑制する」ライフサイエンス新着レビュー 3月14日掲載 Link
榊原恵子 (2013)「コケ植物のエボデボから見えてきた胞子体の複雑化」あんな形，こんなできかた―エボデボ研究最前線［植物篇］生物の科学遺伝 1月号：39-44Link嶋村正樹(
嶋村正樹・榊原恵子 (2011)「微細形態観察法」コケ類研究の手引き（日本蘚苔類学会監修）：113-121
嶋村正樹・西山智明・榊原恵子（2021）「陸上植物起源研究の最後のフロンティア、ツノゴケの生物学」
受賞歴
植物学会奨励賞(日本植物学会)
広島大学学長賞(広島大学)
進化学会奨励賞 (日本進化学会)