Jonathan Ashby

Academic Training


  • 2009 - B.S., Trinity College, Hartford, CT

    • Research Advisor: Janet Morrison

    • Research Topic: Supercritical fluid extraction of pesticides from human hair

  • 2014 - Ph.D., University of California, Riverside, CA

    • Research Advisor: Wenwan Zhong

    • Research Topic: High-throughput methods for probing biomacromolecular interactions

  • 2014-2016: Postdoctoral Fellow, University of California, Davis,

    • Research Advisor: Sheila David

    • Research Topic: Affinity purification-mass spectrometry of DNA repair enzymes

Contact Info

Office: Carr G02B

Office Phone: 413.538.3695

Laboratory: Carr G05

Email: jashby@mtholyoke.edu

Curriculum Vitae

What got you interested in Chemistry? I would say that my interest in chemistry came from two sources. The first was a general chemistry presentation that I gave freshman year on Zubbles, colored soap bubbles that would lose color upon application of energy. Through this presentation (and the many physiochemical properties that these bubbles exploited), I realized just how relevant chemistry was to everyday life. The nature of the colored dyes also excited me (no pun intended): As a result, some of my research interests utilize sensors that have some sort of color change upon a change in the environment.


The other major point that got me interested in chemistry was the amazing teachers, professors and mentors that I had throughout the years. Many people consider chemistry (and STEM in general) as this unapproachable, impossible field to study, and these educators figured out ways to tie chemistry back to real-world applications. They served as my inspiration to go into academia, as well as my (sometimes ridiculous) desire to tie chemical processes in the classroom back to real-world applications and/or pop culture (mostly the first, sometimes the second).

Ashby Lab Questionnaire:

If I had a superpower, it would be: the power to teleport, to visit friends and family across the globe in a snap.

If I could travel anywhere, I would go to: Either Hong Kong or New Zealand, depending on whether it's rugby season.

My spirit animal is: a fennec fox. I'm not sure why, but it is. ((The answer is probably definitely due to Pokemon))

If I were an element, I would be: Cadmium - it's used to make quantum dots for fluorescence-based sensing, as well as in some inorganic pigments. Beware of its toxicity, though!

Awards & Accolades

(2020) - SACP Undergraduate Analytical Research Program mini-grant - Learn More

(2020) - Pittsburgh Conference Memorial National Conference Grant - Learn More

(2019) - Chair, 2019 Annual Meeting of the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers

More information on NOBCChE 2019 Conference Report

(2016-2018) – Consortium for Faculty Diversity Fellowship, Mount Holyoke College - Learn More

(2015-2016) - National Research Council Ford Foundation Postdoctoral Fellowship - Learn More

(2014-2015) - T32 Postdoctoral Training Fellowship (UC Davis, Oncogenic Sig. & Chromosome Bio.) - Learn More

(2014) - Runner-up, AAAS Pacific Division Awards of Excellence, Chemistry/Biochemistry Division

(2011-2014) - National Science Foundation Graduate Research Fellowship - Learn More

Selected Publications

(Undergraduate researchers bolded, co-first authors labeled with an *)

Full list of publications



Ashby, Jonathan; Ligans, Erik; Tamsi, Michael; Zhong, Wenwan. High-throughput profiling of nanoparticle-protein interactions by fluorescamine labeling. Anal. Chem. 2015, 87, 2213-2219. (view abstract)




Ashby, Jonathan*; Flack, Kenneth*; Jimenez, Luis; Duan, Yaokai; Kareem-Khatib, Abdel; Somlo, George; Wang, Shizen Emily, Cui, Xinping; Zhong, Wenwan. Distribution profiling of circulating micro-RNAs in serum. Anal. Chem. 2014, 86, 9343-9349. (view abstract)


Ashby, Jonathan; Pan, Songquin; Zhong, Wenwan. Size and surface functionalization of iron oxide nanoparticles influence the composition and dynamic nature of their protein corona. ACS Appl. Mater. Interfaces. 2014, 6, 15412-15419. (view abstract)



Ashby, Jonathan*; Schachermeyer, Samantha*; Duan, Yaokai; Jimenez, Luis; Zhong, Wenwan. Probing and Quantifying DNA-protein interactions with asymmetrical flow field-flow fractionation. J. Chrom. A. 2014, 1358, 217-224. (view abstract)