The STEM strand of Miriam College Nuvali offers the following subjects for future STEM students: General Chemistry, General Mathematics, Empowerment Technology, Precalculus, Basic Calculus, General Physics, General Biology, Earth and Life Science, and Research.

General Mathematics focuses on the different types of functions such as inverse functions and logarithmic functions. This subject also introduces business mathematics to its students.

Precalculus offers students the knowledge needed to study Calculus. A few topics covered by this subject are the following: Conic sections, series and sequences, mathematical induction, and trigonometric functions.

Basic Calculus focuses on differentiation through the study of limits, continuity, derivatives, and integration.

Probability and Statistics focuses on the skills in calculating the probability of results and analyzing data.

General Chemistry focuses on the interactions between the molecules and the atoms. This subject focuses on the different matters interactions, and how these matters react with each other.

General physics focuses on how matter, motion, and energy work in our everyday lives.

General Biology focuses on the living matters of Earth from the basic unit of life, the cell. This also includes how living things are affected by external factors.

Earth and Life Science focuses on the different structures and processes happening on Earth. A few topics covered by this subject are the following: ecology, minerals, and atmosphere.

Empowerment Technologies focuses on improving computer skills with the use of different productivity tools available.

Research offers students an opportunity to learn about the different steps required in research while also learning about a topic of their own interest.