DNA and The Central Dogma
NGSS-LW Link
Inheritance and Variation of Traits help students in pursuing an answer to the question: “How are the characteristics from one generation related to the previous generation?” High school students demonstrate understanding of the relationship of DNA and chromosomes in the processes of cellular division that pass traits from one generation to the next. Students can determine why individuals of the same species vary in how they look, function, and behave. Students can develop conceptual models for the role of DNA in the unity of life on Earth and use statistical models to explain the importance of variation within populations for the survival and evolution of species. Ethical issues related to genetic modification of organisms and the nature of science can be described. Students can explain the mechanisms of genetic inheritance and describe the environmental and genetic causes of gene mutation and the alteration of gene expression. Crosscutting concepts of structure and function, patterns, and cause and effect developed in this topic help students to generalize understanding of inheritance of traits to other applications in science.
DNA Replication and Protein Synthesis.pptDNA Lecture
Modeling DNA Replication.docx10_Active_Lecture_Questions.pptDNA and Chromosomes
DNA From the Beginning -step by step tutorial on the discovery of genes, DNA, and how they control traits
Modeling Chromosomal Inheritance – use pipe cleaners to show how genes are inherited; independent assortment, segregation, sex-linkage
Linkage Group Simulation – uses pipe cleaners and beads, students construct chromosomes with alleles and perform crosses, predicting outcomes (advanced)
Karyotyping Online – use a website simulator to learn how to pair chromosomes and diagnose abnormalities
Karyotyping Online II – another simulation on how to construct a karyotype
Chromosome Study – cut out chromosomes and tape them in pairs to construct a “paper” karyotype
Gender and Sex Determination – NOVA explores how sex is determined, and social issues of gender
DNA Coloring – basic image of DNA and RNA
DNA Crossword – basic terms
How Can DNA Replication Be Modeled – students use colored paperclips to model how one side of the DNA serves as a template during replication (semi-conservative)
DNA Analysis: Recombination – simulate DNA recombination using paper slips and sequences
DNA Extraction – instructions for extracting DNA from a strawberry, very simple, works every time!
Ramalian DNA – imagine an alien species that has triple-stranded DNA, base pair rules still apply
Who Ate The Cheese – simulate gel electrophoresis to solve a crime
HIV Coloring – shows how viral DNA enters and infects a cell
Genetic Science Ethics – survey as a group ethical questions involved genetics (cloning, gene therapy..)
The Central Dogma
Notes: Transcription and Translation
How DNA Controls the Workings of the Cell
Genetic Science Learning Center
DNA in Snorks – analyze and transcribe DNA sequences, construct a creature based on that sequence
DNA.docxdna, rna, and protein synthesis booklet.docxprotein_synthesis_ws[1].pdf