From the north: Travel I-95 South into South Carolina. Follow I-95 to Exit 181A. Turn left onto SC Hwy. 38. Follow Hwy. 38 to the intersection of US Hwy. 501. Turn right onto Hwy. 501 and proceed to Conway/Myrtle Beach. Continue on Hwy. 501 through Conway and Coastal Carolina University will be on the right. Turn right onto University Blvd. at the stoplight with the Coastal Carolina University sign. Tours begin in the rotunda at the rear of Bill Baxley Hall.

From the south: Travel I-95 North. Take Exit 170. Follow SC Hwy. 327 to the intersection with SC Hwy. 576. Turn left onto Hwy. 576 and follow toward Conway/Myrtle Beach. Hwy. 576 will merge with Hwy. 501. Follow Hwy. 501 through Conway and Coastal Carolina University will be on the right. Turn right onto University Blvd. at the stoplight with the Coastal Carolina University sign. Tours begin in the rotunda at the rear of Bill Baxley Hall.

From Columbia, South Carolina: Take I-20 to I-95. Go north on I-95. Take Exit 170. Follow SC Hwy. 327 to the intersection with SC Hwy. 576. Turn left onto Hwy. 576 and follow toward Conway/Myrtle Beach. Hwy. 576 will merge with Hwy. 501. Follow Hwy. 501 through Conway and Coastal Carolina University will be on the right. Turn right onto University Boulevard. at the stoplight with the Coastal Carolina University sign. Tours begin in the rotunda at the rear of Bill Baxley Hall.