Meta-analysis of OMICs Data

• Methods and principles of meta-analysis (4 hours): 

  • effect sizes, 

  • statistical methods, 

  • bias, 

  • meta-regression

• Multivariate methods of meta-analysis (4 hours): 

  • genetic association data, 

  • diagnostic tests, 

  • multiple outcomes 

  • multiple treatments

Meta-analysis of gene expression and genomewide association data (4 hours): 

• • differentially expressed genes 

  • GWAS

Gene Set Enrichment Analysis (GSEA) (4 hours): 

• Over-representation analysis (ORA), 

  • Functional Class Scoring (FCS), 

  • Pathway Topology (PT) methods