Embedded Files
2024:
1.Microbial Ecology and Metabolism of Emerging Adulthood: Gut Microbiome Insights from a College Freshman Cohort.Mohr AE, Jasbi P, van Woerden I, Chi J, Gu H, Bruening M, Whisner CM.Gut Microbes Rep. 2024;1(1):1-23. doi: 10.1080/29933935.2024.2387936. Epub 2024 Aug 19.PMID: 39221110
Sládeková L, Li H, DesMarais VM, Beck AP, Guzik H, Vyhlídalová B, Gu H, Mani S, Dvořák Z.bioRxiv [Preprint]. 2024 Jul 30:2024.07.30.605845. doi:10.1101/2024.07.30.605845.PMID: 39211241 Free PMC article.
3.Metabolite Predictors of Breast and Colorectal Cancer Risk in the Women's Health Initiative.Navarro SL, Williamson BD, Huang Y, Nagana Gowda GA, Raftery D, Tinker LF, Zheng C, Beresford SAA, Purcell H, Djukovic D, Gu H, Strickler HD, Tabung FK, Prentice RL, Neuhouser ML, Lampe JW.Metabolites. 2024 Aug 20;14(8):463. doi: 10.3390/metabo14080463.PMID: 39195559 Free PMC article.
4.Dietary modulation of Lung Lipids Influences Inflammatory Responses to Inhaled Ozone.Hunter R, Baird B, Mazloumi-Bakhshayesh M, Goitom S, Lucas S, Herbert G, Scieszka D, Davis E, Gu H, Jin Y, Bleske BE, Campen MJ.J Lipid Res. 2024 Aug 23:100630. doi: 10.1016/j.jlr.2024.100630. Online ahead of print.PMID: 39182607 Free article.
5.Artificial Intelligence in Metabolomics: A Current Review.Chi J, Shu J, Li M, Mudappathi R, Jin Y, Lewis F, Boon A, Qin X, Liu L, Gu H.Trends Analyt Chem. 2024 Sep;178:117852. doi: 10.1016/j.trac.2024.117852. Epub 2024 Jul 3.PMID: 39071116
6.Joint exome and metabolome analysis in individuals with dyslexia: Evidence for associated dysregulations of olfactory perception and autoimmune functions.Nandakumar R, Shi X, Gu H, Kim Y, Raskind WH, Peter B, Dinu V.bioRxiv [Preprint]. 2024 Jul 2:2024.06.27.600448. doi: 10.1101/2024.06.27.600448.PMID: 39005457 Free PMC article. Preprint.
7.Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction. Mohr AE, Sweazea KL, Bowes DA, Jasbi P, Whisner CM, Sears DD, Krajmalnik-Brown R, Jin Y, Gu H, Klein-Seetharaman J, Arciero KM, Gumpricht E, Arciero PJ.Nat Commun. 2024 May 28;15(1):4155. doi: 10.1038/s41467-024-48355-5.PMID: 38806467 Free PMC article. Clinical Trial.
Howard EJ, Meyer RK, Weninger SN, Martinez T, Wachsmuth HR, Pignitter M, Auñon-Lopez A, Kangath A, Duszka K, Gu H, Schiro G, Laubtiz D, Duca FA.
J Nutr. 2024 Jul;154(7):2014-2028. doi: 10.1016/j.tjnut.2024.05.003. Epub 2024 May 10.PMID: 38735572 Free PMC article.
9.Single-cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a proinflammatory metabolic signature in male mice at late adulthood. Lim JJ, Goedken M, Jin Y, Gu H, Cui JY.Toxicol Sci. 2024 Jun 26;200(1):114-136. doi: 10.1093/toxsci/kfae047.PMID: 38648751
Dedon LR, Yuan H, Chi J, Gu H, Arias AJ, Covault JM, Zhou Y.medRxiv [Preprint]. 2024 Apr 3:2024.04.02.24305199. doi: 10.1101/2024.04.02.24305199.
PMID: 38633809 Free PMC article.
Garcia MM, Romero AS, Merkley SD, Meyer-Hagen JL, Forbes C, Hayek EE, Sciezka DP, Templeton R, Gonzalez-Estrella J, Jin Y, Gu H, Benavidez A, Hunter RP, Lucas S, Herbert G, Kim KJ, Cui JY, Gullapalli RR, In JG, Campen MJ, Castillo EF.
Environ Health Perspect. 2024 Apr;132(4):47005. doi: 10.1289/EHP13435. Epub 2024 Apr 10.
PMID: 38598326 Free PMC article.
Thumsi A, Martínez D, Swaminathan SJ, Esrafili A, Suresh AP, Jaggarapu MMC, Lintecum K, Halim M, Mantri SV, Sleiman Y, Appel N, Gu H, Curtis M, Zuniga C, Acharya AP. Adv Healthc Mater. 2024 Mar 12:e2303995. doi: 10.1002/adhm.202303995. Online ahead of print.
PMID: 38469995
13. Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension. Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M, Rafikov R, Gu H, de Jesus Perez V, Lemay SE, Glembotski CC, Knox KS, Bonnet S, Kalinichenko VV, Zhao YY, Fallon MB, Boucherat O, Dai Z.bioRxiv [Preprint]. 2024 Apr 15:2024.02.11.579846. doi: 10.1101/2024.02.11.579846.PMID: 38370670 Free PMC article.
2023:
1.M. Yegambaram, X. Sun, Q. Lu, Y. Jin, W. Ornatowski, J. Soto, S. Aggarwal, T. Wang, K. Tieu, H. Gu, J. Fineman,
S. Black, “Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities
of electron transport chain complexes I and III”, Free Radic. Biol. Med., 210, 183, 2023. PMID: 37979892
2. C. Zheng, Y. Luo, Y. Lai, Z. Ilhan, A. Ontiveros-Valencia, R. Krajmalnik-Brown, Y. Jin, H. Gu, X. Long, D. Zhou, B.
Rittmann, “Identifying biodegradation pathways of cetrimonium bromide (CTAB) using metagenome,
metatranscriptome, and metabolome tri-omics integration”, Water Res., 246, 120738, 2023. PMID: 37866246
3. K. Singh, B. Cooper, C. Tofthagen, J. Fryer, P. Singh, K. Pituch, Q. Zhu, H. Gu, M. Hammer, Y. Conley, J. Levine, C.
Miaskowski, “Higher Levels of Stress and Neuropsychological Symptoms Are Associated With a High Nausea Profile
in Patients With Cancer Receiving Chemotherapy”, Oncol. Nurs. Forum, 50, 461, 2023. PMID: 37677748
4. S. Wilson, R. Crosley-Lyons, J. Junk, K. Hasanaj, M. Larouche, K. Hollingshead, H. Gu, C. Whisner, D. Sears, M.
Buman, “Effects of Increased Standing and Light-Intensity Physical Activity to Improve Postprandial Glucose in
Sedentary Office Workers: Protocol for a Randomized Crossover Trial”, JMIR Res. Protoc., 12, e45133, 2023. PMCID: PMC10483290
5. D. Scieszka, Y. Jin, S. Noor, E. Barr, M. Garcia, J. Begay, G. Herbert, R. Hunter, K. Bhaskar, R. Kumar, R.
Gullapalli, A. Bolt, M. McCormick, B. Bleske, H. Gu, M. Campen, “Biomass smoke inhalation promotes
neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice”, J. Neuroinflammation,
20, 192, 2023. PMCID: PMC10464132
6. M. Garcia, S. Matsuzaki, A. Batushansky, R. Newhardt, C. Kinter, Y. Jin, S. Mann, M. Stout, H. Gu, Y. Chiao, M.
Kinter, K. Humphries, “Increased cardiac PFK-2 protects against high-fat diet-induced cardiomyopathy and mediates
beneficial systemic metabolic effects”, iScience, 26, 107131, 2023. PMCID: PMC10391959
7. Y. Jin, J. Chi, K. LoMonaco, A. Boon, H. Gu, “Recent Review on Selected Xenobiotics and Their Impacts on Gut
Microbiome and Metabolome”, Trends Anal. Chem., 166, 117155, 2023. PMCID: PMC10361410
8. X. Qian, T. Srinivasan, J. He, J. Lu, Y. Jin, H. Gu, R. Chen, “Ceramide compensation by ceramide synthases
preserves retinal function and structure in a retinal dystrophy mouse model”, Dis. Model Mech., 16, dmm050168.,
2023. PMCID: PMC10387349
9. S. Templeton, C. McVeigh, C. Nguyen, R. Hunter, D. Scieszka, G. Herbert, E. Barr, R. Liu, H. Gu, B. Bleske, M.
Campen, A. Bolt, “Acute inhalation of tungsten particles results in early signs of cardiac injury”, Toxicol. Lett., 384,
52, 2023. PMCID: PMC10528412
10. D. Scieszka, Y. Jin, S. Noor, E. Barr, M. Garcia, J. Begay, G. Herbert, R. Hunter, K. Bhaskar, R. Kumar, R.
Gullapalli, A. Bolt, M. McCormick, B. Bleske, H. Gu, M. Campen, “Neuroinflammatory and Metabolomic Temporal
Dynamics Following Wood Smoke Inhalation”, Res. Sq., rs.3.rs-3002040, 2023. PMCID: PMC10275049
11. S. Kim, H. Li, Y. Jin, J. Armad, H. Gu, S. Mani, J. Cui, “Maternal PBDE exposure disrupts gut microbiome and
promotes hepatic proinflammatory signaling in humanized PXR-transgenic mouse offspring over time”, Toxicol. Sci.,
194, 209, 2023. PMCID: PMC10375318
12. D. Scieszka, D. Garland, R. Hunter, G. Herbert, S. Lucas, Y. Jin, H. Gu, M. Campen, J. Cannon, “Multi-omic
assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure”, Respir. Res., 24,
138, 2023. PMCID: PMC10209577
13. P. Jasbi, J. Nikolich-Žugich, J. Patterson, K. Knox, Y. Jin, G. Weinstock, P. Smith, H. Twigg, H. Gu, “Targeted
metabolomics reveals plasma biomarkers and metabolic alterations of the aging process in healthy young and older
adults”, Geroscience, doi: 10.1007/s11357-023-00823-4, 2023. PMID: 37195387
S. Inamdar, A. Suresh, J. Mangal, N. Ng, A. Sundem, H. Behbahani, T. Rubino Jr, X. Shi, S. Loa, J. Yaron, T.
Hitosugi, M. Green, H. Gu, M. Curtis, A. Acharya, “Succinate based polymers drive immunometabolism in dendritic
cells to generate cancer immunotherapy”, J. Control Release, 358, 541, 2023. PMCID: PMC10324539
15. W. Pederson, L. Ellerman, Y. Jin, H. Gu, J. Ledford, “Metabolomic Profiling in Mouse Model of Menopause-
Associated Asthma”, Metabolites, 13, 546, 2023. PMCID: PMC10145474
16. C. Zheng, Y. Luo, X. Long, H. Gu, J. Cheng, L. Zhang, Y. Lai, B. E. Rittmann, “The structure of biodegradable
surfactants shaped the microbial community, antimicrobial resistance, and potential for horizontal gene transfer”,
Water Res., 236, 119944, 2023. PMID: 37087920
17. Y. Mi, G. Qi, F. Vitali, Y. Shang, A. C. Raikes, T. Wang, Y. Jin, R. D. Brinton, H. Gu, F. Yin, “Loss of fatty acid
degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration”, Nat Metab., 5, 445,
2023. PMID: 36959514
18. S. Sangam, X. Sun , T. Schwantes-An, M. Yegambaram, Q. Lu, Y. Shi, T. Cook, A. Fisher, A. L. Frump, A. Coleman,
Y. Sun, S. Liang, H. Crawford, K. A. Lutz, A. D. Maun, M. W. Pauciulo, J. H. Karnes, K. R. Chaudhary, D. J. Stewart,
P. R. Langlais, M. Jain, M. Alotaibi, T. Lahm, Y. Jin, H. Gu, H. Tang, W. C. Nichols, S. M. Black, A. A. Desai, “SOX17
Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics”, Am J Respir
Crit Care Med., doi: 10.1164/rccm.202203-0450OC, 2023. PMID: 36913491
19. H. Diao, H. Gu, Q. M. Chen, “Hyperkalemic or Low Potassium Cardioplegia Protects against Reduction of Energy
Metabolism by Oxidative Stress”, Antioxidants, 12, 452, 2023. PMCID: PMC9952220
2022:
1. S. Sangam, X. Sun , T. Schwantes-An, M. Yegambaram, Q. Lu, Y. Shi, T. Cook, A. Fisher, A. L. Frump, A. Coleman,
Y. Sun, S. Liang, H. Crawford, K. A. Lutz, A. D. Maun, M. W. Pauciulo, J. H. Karnes, K. R. Chaudhary, D. J. Stewart,
P. R. Langlais, M. Jain, M. Alotaibi, T. Lahm, Y. Jin, H. Gu, H. Tang, W. C. Nichols, S. M. Black, A. A. Desai, “SOX17
Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics”, Am J Respir
Crit Care Med., doi: 10.1164/rccm.202203-0450OC, 2023. PMID: 36913491
2. H. Diao, H. Gu, Q. M. Chen, “Hyperkalemic or Low Potassium Cardioplegia Protects against Reduction of Energy
Metabolism by Oxidative Stress”, Antioxidants, 12, 452, 2023. PMCID: PMC9952220
3. A. E. Mohr, P. Jasbi, D. A. Bowes, B. Dirks, C. M. Whisner, K. M. Arciero, M. Poe, H. Gu, E. Gumpricht, K. L.
Sweazea, P. J. Arciero, “Exploratory analysis of one versus two-day intermittent fasting protocols on the gut
microbiome and plasma metabolome in adults with overweight/obesity”, Front Nutr., 9, 1036080, 2022. PMCID:
PMC9644216
4. D. Brister, S. Rose, L. Delhey, M. Tippett, Y. Jin, H. Gu, R. E. Frye, “Metabolomic Signatures of Autism Spectrum
Disorder”, J Pers Med., 12, 1727, 2022. PMCID: PMC9604590
5. T. Liu, Y. Wang, Y. Wang, S. K. Cheung, P. M. Or, C. Wong, J. Guan, Z. Li, W. Yang, Y. Tu, J. Wang, W. L. Ho, H.
Gu, A. S. Cheng, S. K. Tsui, A. M. Chan, “The mitotic regulator RCC2 promotes glucose metabolism through
BACH1-dependent transcriptional upregulation of hexokinase II in glioma”, Cancer Lett., 549, 215914, 2022. PMID:
36116740
6. H. He, T. Pan, X. Shi, S. Yang, P. Jasbi, Y. Jin, J. Y. Cui, H. Gu, “An integrative cellular metabolomic study reveals
downregulated tricarboxylic acid cycle and potential biomarkers induced by tetrabromobisphenol A in human lung
A549 cells”, Environ. Toxicol., doi: 10.1002/tox.23657, 2022. PMID: 36106841
7. X. Qian, H. Liu, S. Fu, J. Lu, Y. Hung, C. Turner, H. Gu, R. Chen, “AAV8-Mediated Gene Therapy Rescues Retinal
Degeneration Phenotype in a Tlcd3b Knockout Mouse Model”, Invest. Ophthalmol. Vis. Sci., 63, 11, 2022. PMCID:
PMC8934561
8. N. Hwangbo, X. Zhang, D. Raftery, H. Gu, S. Hu, T. Montine, J. Quinn, K. Chung, A. Hiller, D. Wang, Q. Fei, L.
Bettcher, C. Zabetian, E. Peskind, G. Li, D. Promislow, M. Davis, A. Franks, “Predictive Modeling of Alzheimer's and
Parkinson's Disease Using Metabolomic and Lipidomic Profiles from Cerebrospinal Fluid”, Metabolites, 12, 277,
2022. PMCID: PMC9029812
9. D. Brister, B. Werner, G. Gideon, P. McCarty, A. Lane, B. Burrows, S. McLees, P. Adelson, J. Arango, W. Marsh, A.
Flores, M. Pankratz, N. Ly, M. Flood, D. Brown, D. Carpentieri, Y. Jin, H. Gu, R. Frye, “Central Nervous System
Metabolism in Autism, Epilepsy and Developmental Delays: A Cerebrospinal Fluid Analysis”, Metabolites, 12, 371,2022. PMCID: PMC9148155
10. K. Singh, K. Pituch, Q. Zhu, H. Gu, B. Ernst, C. Tofthagen, M. Brewer, K. Kober, B. Cooper, S. Paul, Y. Conley, M.
Hammer, J. Levine, C. Miaskowski, “Distinct Nausea Profiles Are Associated With Gastrointestinal Symptoms in Oncology Patients Receiving Chemotherapy”, Cancer Nurs., 10, 1097/NCC.0000000000001076, 2022. PMCID:PMC9437145
B. Xu, F. Li, W. Zhang, Y. Su, L. Tang, P. Li, J. Joshi, A. Yang, D. Li, Z. Wang, S. Wang, J. Xie, H. Gu, W. Zhu,
“Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection”, iScience, 25,
104447, 2022. PMCID: PMC9189130
11. J. Poole, P. Jasbi, A. Pascual, S. North, N. Kwatra, V. Weissig, H. Gu, T. Bottiglieri, N. Jadavji, “Ischemic Stroke and
Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size,
and Changed Metabolite Profiles in Brain and Cecum Tissue”, Nutrients, 14, 2960, 2022. PMCID: PMC9318046
12. A. Mohr, P. Jasbi, K. Vander Wyst, I. van Woerden, X. Shi, H. Gu, C. Whisner, M. Bruening, “Association of food
insecurity on gut microbiome and metabolome profiles in a diverse college-based sample”, Sci. Rep., 12, 14358,
2022. PMCID: PMC9399224
13. T. Liu, Y. Wang, Y. Wang, S. Cheung, P. Or, C. Wong, J. Guan, Z. Li, W. Yang, Y. Tu, J. Wang, W. Ho, H. Gu, A.
Cheng, S. Tsui, A. Chan, “The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent
transcriptional upregulation of hexokinase II in glioma”, Cancer Lett., 549, 215914, 2022. PMID: 36116740
14. D. Brister, S. Rose, L. Delhey, M. Tippett, Y. Jin, H. Gu, R. Frye, “Metabolomic Signatures of Autism Spectrum
Disorder”, J. Pers. Med., 12, 1727, 2022. PMCID: PMC9604590
15. M. Little, M. Dutta, H. Li, A. Matson, X. Shi, G. Mascarinas, B. Molla, K. Weigel, H. Gu, S. Mani, J. Yue Cui,
“Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut
microbiome using genetically modified mice”, Acta Pharm. Sin. B, 12, 801-820, 2022. PMID: 35256948
16. P. Jasbi, A. Mohr, X. Shi, T. Mahmood, Q. Zhu, M. Bruening, H. Gu, C. Whisner, “Microbiome and metabolome
profiles of high screen time in a cohort of healthy college students”, Sci. Rep., 12, 3452, 2022. PMCID: PMC8891328
17. C. Zhu, H. Gu, Y. Jin, D. Wurm, B. Freidhof, Y. Lu, Q. Chen, “Metabolomics of oxidative stress: Nrf2 independent
depletion of NAD or increases of sugar alcohols”, Toxicol. Appl. Pharmacol., 442, 115949, 2022. PMID: 35227738
18. T. Young, D. Scieszka, J. Begay, S. Lucas, G. Herbert, K. Zychowski, R. Hunter, R. Salazar, A. Ottens, A. Erdely, H.
Gu, M. Campen, “Aging influence on pulmonary and systemic inflammation and neural metabolomics arising from
pulmonary multi-walled carbon nanotube exposure in apolipoprotein E-deficient and C57BL/6 female mice”, Inhal.
Toxicol., 1-15, 2022. PMID: 35037817
19. D. Scieszka, R. Hunter, J. Begay, M. Bitsui, Y. Lin, J. Galewsky, M. Morishita, Z. Klaver, J. Wagner, J. Harkema, G.
Herbert, S. Lucas, C. McVeigh, A. Bolt, B. Bleske, C. Canal, E. Mostovenko, A. Ottens, H. Gu, M. Campen, S. Noor,
“Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter
in the Western United States”, Toxicol. Sci., 186, 149-162, 2022. PMCID: PMC8883349
20. K. P. Singh, K. M. Kober, B. Ernst, J. Sachdev, M. Brewer, Q. Zhu, H. Gu, M. Melisko, S. M. Paul, B. A. Cooper, M.
Hammer, Y. P. Conley, J. D. Levine, C. Miaskowski, “Multiple Gastrointestinal Symptoms Are Associated With
Chemotherapy-Induced Nausea in Patients With Breast Cancer”, Cancer Nurs., 45, 181-189, 2022. PMID: 34183520
2021:
G. Qi, Y. Mi, X. Shi, H. Gu, R.D. Brinton, F. Yin "ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism" J. Cell Reports, 34, 108572 PMID: 31969828
A. J. Basile, A. E. Mohr, P. Jasbi‡, H. Gu, P. Deviche, and K. L. Sweazea*, “A four-week high fat diet does not alter plasma glucose or metabolic physiology in wild-caught mourning doves (Zenaida macroura)”, Comp. Biochem. Physiol. A. Mol. Integr. Physiol., 251, 110820, 2021. PMID: 33053437
C. Zheng, G A Nagana Gowda, D. Raftery, M. Neuhouser, L. Tinke, R. Prentice, S. Beresford, Y. Zhang, L. Bettche, R. Pepin, D. Djukovic, H. Gu, G. Barding Jr, X. Song, J. Lampe "Evaluation of potential metabolomic-based biomarkers of protein, carbohydrate and fat intakes using a controlled feeding study" European Journal of Nutrition, Online ahead of print, PMID: 33991228
Y. Wei, P. Jasbi, X. Shi, C. Turner, J. Hrovat, L. Liu, Y. Rabena, P. Porter, H. Gu "Early Breast Cancer Detection Using Untargeted and Targeted Metabolomics" Journal of Proteome Research, Online ahead of print, PMID: 34033488
H. Gu, P. Jasbi, J. Patterson, Y. Jin "Enhanced Detection of Short-Chain Fatty Acids Using Gas Chromatography Mass Spectrometry" Current Protocols, 1, e177., PMID: Pending doi: 10.1002/cpz1.177
P. Jasbi, X. Shi, P Chu, N. Elliott, H. Hudson, D. Jones, G. Serrano, B. Chow, T. Beach, L. Liu, G. Jentarra, H. Gu. "Metabolic profiling of neocortical tissue discriminates Alzheimer’s disease from mild cognitive impairment, high pathology controls, and normal controls." Journal of Proteome Research, ASAP PMID: Pending
2020:
1. Z. Dvořák, F. Kopp, C. M. Costello, J. S. Kemp, H. Li, A. Vrzalová, M. Štěpánková, I. Bartoňková, E. Jiskrová, K. Poulíková, [...], H. Gu, [...], S. Mani,* "Targeting the pregnane X receptor using microbial metabolite mimicry," EMBO Mol. Med., 12: e11621, PMID: 32153125
2. L. Deng, F. Guo, K. Cheng, J. Zhu, H. Gu, D. Raftery,* J. Dong,* "Identifying Significant Metabolic Pathways Using Multi-Block Partial Least-Squares Analysis," J. of Proteome Research, 19, 5, 1965-1974, PMID: 32174118
3. E. Quarles, N. Basisty, Y.A. Chaio, G. Merrihew, H. Gu, M.T. Sweetwyne, J. Fredrickson, N.H. Nguyen, M. Razumova, K. Kooiker, F. Moussavi-Harami, M. Reginer, C. Quarles, M. MacCoss, P.S. Rabinovitch,* "Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment," J. Aging Cell, 19(2):e13086, PMID: 31823466
4. J.L. Mangal, S. Inamdar, Y. Yang, X. Shi, M. Wankhede, H. Gu, K. Rege, M.D. Green, M. Curtis and A. Acharya,* "Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism," J. of Materials Chemistry B, Jun 24;8(24):5195-5203. PMID: 32427266
5. R. Eghlimi, X. Shi, J. Hrovat, B. Xi, H. Gu,* "Triple Negative Breast Cancer Detection Using LC-MS/MS Lipidomic Profiling," J. of Proteome Research, 19(6):2367-2378. PMID: 32397718
6. J.J. Lim, X. Li 2, H. Lehmler, D. Wang, H. Gu, J.Y. Cui,* "Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice," Toxicol Sci., kfaa090. PMID: 32544245
7. H. He, X. Shi, A. Lawrence, J. Hrovat, C. Turner, J.Y. Cui*, H. Gu,* "2,2',4,4'-tetrabromodiphenyl Ether (BDE-47) Induces Wide Metabolic Changes Including Attenuated Mitochondrial Function and Enhanced Glycolysis in PC12 Cells," Ecotoxicol. Environ. Saf., 201:110849. PMID: 32559690
8. X. Shi, B. Xi, P. Jasbi, C. Turner, Y. Jin, H. Gu,* "Comprehensive Isotopic Targeted Mass Spectrometry (CIT-MS): Reliable Metabolic Flux Analysis with Broad Coverage," Analytical Chemistry, 1;92(17):11728-11738 . PMID: 32697570
9. A. J. Basile, P. Jasbi‡, W. Clark, X. Shi‡, H. Gu, P. Deviche, and K. L. Sweazea*, “A four-week white bread diet does not alter plasma glucose concentrations, metabolic or vascular physiology in mourning doves, Zenaida macroura”, Comp. Biochem. Physiol. A. Mol. Integr. Physiol., 247, 110718, 2020. PMID: 32376459
10. H. Gu, X. Shi, P. Jasbi, J. Patterson. "Metabolomics Analysis of Viral Therapeutics." Methods Mol Biol. 2021;2225:179-197. PMID: 33108663.
11. M. Gomez, M. Dutta, A. Suvorov, X. Shi, H. Gu, S. Mani, J. Y. Cui. "Early life exposure to environmental contaminants (BDE-47, TBBPA, and BPS) produced persistent alterations in fecal microbiome in adult male mice" Toxicological Sciences, , kfaa161. PMID: 33078840
2019:
1. D. Gutierrez, A. Weinstock, V. Antharam, H. Gu, P. Jasbi, X. Shi, B. Dirks, R. Krajmalnik-Brown, J. Maldonado, J. Guinan, S. Thangamani, "Antibiotic-induced gut metabolome and microbiome alterations increase the susceptibility to Candida albicans colonization in the gastrointestinal tract," FEMS Microbiol. Ecol., pii: fiz187, 2019, PMID: 31769789
2. G. Kurgan, L. Kurgan, A. Schneider, M. Onyeabor, Y. Rodriguez-Sanchez, E. Taylor, R. Martinez, P. Carbonell, X. Shi, H. Gu., X. Wang*, "Identification of major malate export systems in an engineered malate-producing Escherichia coli aided by substrate similarity search," Appl. Microbiol. Biotechnol., 103(21-22):9001-9011, 2019, PMID: 31641813
3. R.L. Burr, H. Gu, K. Cain, D. Djukovic, X. Zhang, C. Han, N. Callan, D. Raftery, M. Heitkemper, "Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study," J. Neurogastroenterol. Motil., 25(4):551-562, 2019, PMID: 31587547
4. P. Jasbi, O. Baker, X. Shi, L. A. Gonzalez, S. Wang, S. Anderson, B. Xi, H. Gu* and C. S. Johnston*, "Daily red wine vinegar ingestion for eight weeks improves glucose homeostasis and affects the metabolome but does not reduce adiposity in adults," Food & Function, 10(11):7343-7355, 2019, PMID: 31647087.
5. X. Shi, S. Wang, P. Jasbi, C. Turner, J. Hrovat, Y. Wei, J. Liu, and H. Gu*, "Database Assisted Globally Optimized Targeted Mass Spectrometry (dGOT-MS): Broad and Reliable Metabolomics Analysis with Enhanced Identification", Anal. Chem., 91 (21), 13737-13745, 2019, PMID: 31556994
6. X. Wang, H. Gu, S.A. Palma-Duran, A. Fierro, P. Jasbi, X. Shi, W. Bresette, N. Tasevska*, "Influence of Storage Conditions and Preservatives on Metabolite Fingerprints in Urine", Metabolites, 9(10). pii: E203, 2019, PMID: 31569767
7. D. K. Scoville, C. Y. Li, D. Wang, J. L. Dempsey, D. Raftery, S. Mani, H. Gu* and J. Y. Cui*, "Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice", Drug Metab. Dispos., 47 (8), 928-940, 2019, PMID: 31123037
8. J. Dempsey, D. Wang, G. Siginir, Q. Fei, D. Raftery, H. Gu, J. Y. Cui*, “Pharmacological Activation of PXR and CAR Downregulates Distinct Bile Acid-Metabolizing Intestinal Bacteria and Alters Bile Acid Homeostasis”, Toxicol Sci., 168, 40-60, 2019. PMID: 30407581
9. P. Jasbi, N. M. Mitchell, X. Shi, T. E. Grys, Y. Wei, L. Liu, D. F. Lake, and H. Gu*, "Coccidioidomycosis Detection Using Targeted Plasma and Urine Metabolic Profiling." J. of Proteome Research, 18, 7, 2791-2802, 2019. PMID: 31244214
10. P. Jasbi, D. Wang, L. Cheng, Q. Fei, Y. Cui, L. Liu, Y. Wei, D. Raftery, H. Gu*, “Breast cancer detection using targeted plasma metabolomics”, J. Chromatogr B, 1105:26-37, 2019. PMID: 30562627
11. Q. Fei, D. Wang, P. Jasbi, P. Zhang, G. A. Nagana Gowda, D. Raftery, and H. Gu*, "Combining NMR and MS with Chemical Derivatization for Absolute Quantification with Reduced Matrix Effects", Analytical Chemistry, 91(6):4055-4062, 2019. PMID: 30801179
12. X. Zhang, X. Xie, B. Heckmann, A. Saarinen, H. Gu, R. Zechner, and J. Liu, "Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)", FASEB J., 33(5):6655-6666, 2019 PMID: 30802154
13. B. Zhua, H. Cao, G. Li, W. Du, G. Xu, J. Santo Domingo, H. Gu, N. Xu, S. Duan, J. Lu, "Biodiversity and dynamics of cyanobacterial communities during blooms in temperate lake (Harsha Lake, Ohio, USA)", J. Harmful Algae, 82, 9-18, 2019. PMID: 30928013
14. S. L. Navarro, A. Tarkhan, A. Shojaie, T. W. Randolph, H. Gu, D. Djukovic, K. J. Osterbauer, M. A. Hullar, M. Kratz, M. L. Neuhouser, P. D. Lampe, D. Raftery, J. W. Lampe, "Plasma metabolomics profiles suggest beneficial effects of a low–glycemic load dietary pattern on inflammation and energy metabolism", The American Journal of Clinical Nutrition, 110(4):984-992, 2019. PMID: 31432072
2018:
1. D. Wang, X. Sun, J. Yan, B. Ren, B. Cao, Q. Lu, Y. Liu, J. Zeng, N. Huang, Q. Xie, H. Gu*, J. Wang*, “Alterations of eicosanoids and related mediators in patients with schizophrenia”, J Psychiatr. Res., 102:168-178, 2018. PMID: 29674269
2. C. Li, J. L. Dempsey, D. Wang, S. Lee, K. M. Weigel, Q. Fei, D. K. Bhatt, B. Prasad, D. Raftery, H. Gu, J. Y. Cui*, “PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice”, Drug Metab. Dispos., 2018. PMID: 29769268
3. D. Du, H. Gu, D. Djukovic, L. Bettcher, M. Gong, W. Zheng, L. Hu, X. Zhang, R. Zhang, D. Wang, D. Raftery*, “Multiplatform Metabolomics Investigation of Antiadipogenic Effects on 3T3-L1 Adipocytes by a Potent Diarylheptanoid”, J. Proteome Res., 17, 2092-2101, 2018. PMID: 29688022
4. B. N. R. Ginos, S. L. Navarro, Y. Schwarz, H. Gu, D. Wang, T. W. Randolph, A. Shojaie, M. A. J. Hullar, P. D. Lampe, M. Kratz, M. L. Neuhouser, D. Raftery, J. W. Lampe, “Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study”, Metabolism, 83,197-204, 2018. PMCID: PMC5960615
5. R. J. Davis, M. Gönen, D. H. Margineantu, S. Handeli, J. Swanger, P. Hoellerbauer, P. J. Paddison, H. Gu, D. Raftery, J. E. Grim, D. M. Hockenbery, A. A. Margolin, B. E. Clurman, “Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism”, PNAS, 115, 5462-5467, 2018. PMID: 29735700
6. R. Li, S. Grimm, D. Mav, H. Gu, D. Djukovic, R. Shah, B. Merrick, D. Raftery, P. Wade*, “Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer”, Cell Rep., 624-637, 2018. PMCID: PMC5793878
7. G. A. N. Gowda, D. Djukovic, L. Bettcher, H. Gu, D. Raftery*, “NMR-Guided Mass Spectrometry for Absolute Quantitation of Human Blood Metabolites”, Anal. Chem., 90, 2001-2009, 2018. PMID: 29293320
8. J. Liu, Hanavan PD, Kras K, Ruiz YW, Castle EP, Lake DF, Chen X, O'Brien D, Luo H, Robertson KD, H. Gu*, Ho TH*, "Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines toward Enhanced Oxidative Phosphorylation", J. Proteome Res., 2018. PMID: 30406665
9. P. Lohavanichbutr, Y. Zhang, P. Wang, H. Gu, G. A. N. Gowda, D. Djukovic, M. Buas, D. Raftery, C. Chen*, “Salivary metabolite profiling distinguishes patients with oral cavity squamous cell carcinoma from normal controls”, PLoS One, e0204249, 2018. PMCID: PMC6147497
10. D. Shao, O. Villet, Z. Zhang, S. Choi, J. Yan, J. Ritterhoff, H. Gu, D. Djukovic, D. Christodoulou, S. Kolwicz, D. Raftery, R. Tian*, “Glucose promotes cell growth by suppressing branched-chain amino acid degradation”, Nat. Commun., 9, 2935, 2018. PMCID: PMC6062555
11. R. Centini, M. Tsang, T. Iwata, H. Park, J. Delrow, D. Margineantu, B. Iritani, H. Gu, H. Liggitt, J. Kang, L. Kang, D. Hockenbery, D. Raftery, B. Iritani*, “Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation”, PLoS One, e0197973, 2018. PMCID: PMC5999084
12. B. Roshanravan, L. Zelnick, D. Djucovic, H. Gu, J. Alvarez, T. Ziegler, J. Gamboa, K. Utzschneider, B. Kestenbaum, J. Himmelfarb, S. Kahn, D. Raftery, I. de Boer*, “Chronic kidney disease attenuates the plasma metabolome response to insulin”, JCI Insight, 3, e122219, 2018. PMCID: PMC6141172
13. Shuyun Liu, Meng Zhao, Yijie Zhou, Chengshi Wang, Yujia Yuan, Lan Li, W. Bresette, Younan Chen, Jingqiu Cheng, Yanrong Lu*, J. Liu*, "Resveratrol exerts dose-dependent anti-fibrotic or pro-fibrotic effects in kidneys: a potential risk to individuals with impaired kidney function", Phytomedicine, 2018. PHYMED 52801
14) D. Wang, S. Cheng, Q. Fei, H. Gu, D. Raftery, B. Cao, X. Sun, J. Yan, C. Zhang, J. Wang*, “Metabolic profiling identifies phospholipids as potential serum biomarkers for schizophrenia”, Psychiatry Res., 272, 18-29, 2018. PMID: 30579177
2017:
C. Chen, G. A. N. Nagana, J. Zhu, L. Deng, H. Gu, E. G. Chiorean, M. Abu Zaid, M. Harrison, D. Zhang, M. Zhang*, D. Raftery*, “Altered metabolite levels and correlations in patients with colorectal cancer and polyps detected using seemingly unrelated regression analysis”, Metabolomics, 12, 125, 2017.
2. J. R. Chao, K. Knight, A. L. Engel, C. Jankowski, Y. Wang, M. A. Manson, H. Gu, D. Djukovic, D. Raftery, J. B. Hurley, J. Du*, “Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side”, J. Bio. Chem., 292, 12895-12905, 2017. PMCID: PMC5546030
3. F. Miles, S. Navarro, Y. Schwarz, H. Gu, D. Djukovic, T. Randolph, A. Shojaie, M. Kratz, M. Hullar, P. Lampe, M. Neuhouser, D. Raftery, J. Lampe*, “Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets”, Food Funct., 8, 3209-3218, 2017. PMID: 28808723
4. M. Buas, H. Gu, D. Djukovic, J. Zhu, L. Onstad, B. Reid, D. Raftery*, T. Vaughan*, “Candidate serum metabolite biomarkers for differentiating gastroesophageal reflux disease, Barrett's esophagus, and high-grade dysplasia/esophageal adenocarcinoma”, Metabolomics, 13, 23, 2017. PMCID: PMC5295138
5. H. Lu, H. Zhu*, T. Zhu, Y. Xiao, S. Xie, H. Gu, M. Cui, L. Luo, “Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 7, 5136, 2017. PMCID: PMC5506000.
6. T. Li, Z. Zhang, S. Kolwicz, L. Abell, N. Roe, M. Kim, B. Zhou, Y. Cao, J. Ritterhoff, H. Gu, D. Raftery, H. Sun, R. Tian*, “Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury”, Cell Metab., 25, 374-385, 2017. PMCID: PMC5301464.
7. J. Rabinowitz, A. Robitaille, Y. Wang, C. Ray, R. Thummel, H. Gu, D. Djukovic, D. Raftery, J. Berndt, R. Moon*, “Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish”, PNAS, 114, E717-E726, 2017. PMCID: PMC5293114.
2016:
F. Carnevale Neto, A. C. Pilon, D. M. Selegato, R. T. Freire, H. Gu, D. Raftery, N. P. Lopes*, I. Castro-Gamboa*, “Dereplication of Natural Products Using GC-TOF Mass Spectrometry: Improved Metabolite Identification by Spectral Deconvolution Ratio Analysis”, Front. Mol. Biosci., 3, 59, 2016. PMCID: PMC5044510
2. H. Zhao, J. Shen, D. Djukovic, C. Daniel-MacDougall, H. Gu, X. Wu, W. H. Chow, “Metabolomics-identified metabolites associated with body mass index and prospective weight gain among Mexican American women”, Obes. Sci. & Pract., 2, 309-317, 2016. PMCID: PMC5043515
3. H. Gu, J. Du, P. A. Carroll, J. Zhu, F. Carnevale Neto, R. N. Eisenman, D. Raftery*, “Quantitative Method to Investigate the Balance between Metabolism and Proteome Biomass: Starting from Glycine”, Angew. Chem. Int. Ed., 55, 15656-15650, 2016. PMID: 27860107
4. B. Parent*, M. Seaton, R. Sood, H. Gu, D. Djukovic, D. Raftery, G. O'Keefe, “Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients”, JAMA Surg., 151, e160853, 2016. PMID: 27223119
5. L. Deng, H. Gu*, J. Zhu, G. A. Nagana Gowda, D. Djukovic, E. G. Chiorean, D. Raftery*, “Combining NMR and LC/MS Using Backward Variable Elimination: Metabolomics Analysis of Colorectal Cancer, Polyps, and Healthy Controls”, Anal. Chem., 88, 7975-7983, 2016. PMID: 27437783
6. M. Buas, H. Gu, D. Djukovic, J. Zhu, C. W. Drescher, N. Urban, D. Raftery, C. Li*, “Identification of Novel Candidate Plasma Metabolite Biomarkers for Distinguishing Serous Ovarian Carcinoma and Benign Serous Ovarian Tumors”, Gynecol. Oncol., 140, 138-144, 2016. PMID: 26521694
7. M. Heitkemper*, C. Han, M. Jarrett, H. Gu, D. Djukovic, R. Shulman, D. Raftery, W. Henderson, K. Cain, “Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)”, Biol. Res. Nurs., 18, 193-198, 2016. PMID: 26156003
8. J. Du, A. Rountree, W. M. Cleghorn, L. Contreras, K. J. Lindsay, M. Sadilek, H. Gu, D. Djukovic, D. Raftery, J. Satrústegui, M. Kanow, L. Chan, S. H. Tsang, I. R. Sweet, J. B. Hurley*, “Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina”, J. Bio. Chem., 291, 4698-4710, 2016. PMCID: PMC4813492
9. Y. Chiao, S. C. Kolwicz, N. Basisty, A. Gagnidze, J. Zhang, H. Gu, D. Djukovic, R. P. Beyer, D. Raftery, M. MacCoss, R. Tian, P. S. Rabinovitch*, “Rapamycin Transiently Induces Mitochondrial Remodeling to Reprogram Energy Metabolism in Old Hearts”, Aging, 8, 314-327, 2016. PMID: 26872208
10. S. Lim, C. Li, W. Xia, H. Lee, S. Chang, J. Shen, J. Hsu, D. Raftery, D. Djukovic, H. Gu, W. Chang, H. Chang, H. Wang, M. Chen, L. Huo, C. Chen, Y. Wu, A. Sahin, S. Hanash, G. Hortobagyi, M. Hung*, “EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape”, Cancer Res., 76, 1284-1296, 2016. PMCID: PMC4775355
2015:
H. Gu*, P. Zhang, J. Zhu, D. Raftery*, “Globally Optimized Targeted Mass Spectrometry (GOT-MS): Reliable Metabolomics Analysis with Broad Coverage”, Anal, Chem., 87, 12355-12362, 2015. PMID: 26579731
H. Sperber, J. Mathieu, Y. Wang, A. Ferreccio, J. Hesson, Z. Xu, K. A. Fischer, A. Devi, D. Detraux, H. Gu, S. L. Battle, M. Showalter, C. Valensisi, J. H. Bielas, N. G. Ericson, L. Margaretha, A. M. Robitaille, D. Margineantu, O. Fiehn, D. Hockenbery, C. A. Blau, D. Raftery, A. A. Margolin, R. D. Hawkins, R. T. Moon, C. B. Ware, H. Ruohola-Baker*, “The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition”, Nat. Cell Bio., 17, 1523-1535, 2015. PMCID: PMC4662931
J. Zhu, D. Djukovic, L. Deng, H. Gu, F. Himmati, M. Abu Zaid, E. G. Chiorean, D. Raftery*, “Targeted serum metabolite profiling and sequential metabolite ratio analysis for colorectal cancer progression monitoring”, Anal. Bioanal. Chem., 407, 7857-7863, 2015. PMID: 26342311
J. Wang, Q. Li, H. Gu, X. Guo, S. Yang, Z. Wang, “Direct Analysis of Micro Area on Tooth Surface by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry”, Chem. J. Chin. Univ., 36, 1067-1073, 2015.
H. Gu*, J. Du, F. Carnevale Neto, P. Carroll, S. Turner, G. Chiorean, R. Eisenman, D. Raftery, “Metabolomics Method to Comprehensively Analyze Amino Acids in Different Domains”, Analyst, 140, 2726-2734, 2015. PMCID: PMC4380628
P. Carroll, D. Diolaiti, L. McFerrin, H. Gu, D. Djukovic, J. Du, P. Cheng, S. Anderson, M. Ulrich, J. Hurley, D. Raftery, D. Ayer, R. Eisenman*, “Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis”, Cancer Cell, 27, 271-285, 2015. PMCID: PMC4326605
N. Reyes, G. Banks, M. Tsang, D. Margineantu, H. Gu, D. Djukovic, J. Chan, M. Torres, H. Liggitt, D. Hirenallur-S, D. Hockenbery, D. Raftery, B. Iritani*, “Fnip1 Regulates Skeletal Muscle Fiber Type Specification, Fatigue Resistance, and Susceptibility to Muscular Dystrophy”, PNAS, 112, 424-429, 2015. PMCID: PMC4299192
R. Sood, H. Gu, D. Djukovic, L. Deng, M. Ga, L. Muffley, D. Raftery, A. Hocking*, “Targeted Metabolic Profiling of Wounds in Diabetic and Nondiabetic Mice”, Wound Repair Regen., 23, 423-34, 2015. PMID: 25845676
S. Barton, S. Navarro, M. Buas, Y. Schwarz, H. Gu, D. Djukovic, D. Raftery, M. Kratz, M. Neuhouser, J. Lampe*, “Targeted Plasma Metabolome Response to Variations in Dietary Glycemic Load in a Randomized, Controlled, Crossover Feeding Trial in Healthy Adults”, Food Funct., 2015. PMID: 26165375
S. Pan, Y. Tian, M. Li, J. Zhao, L. Zhu, W. Zhang, H. Gu*, H. Wang, J. Shi, X. Fang, P. Li, H. Chen, “Quantitative Detection of Nitric Oxide in Exhaled Human Breath by Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 5, 8725, 2015. PMCID: PMC4348632
C. Chen, L. Deng, S. Wei, G.A.N. Gowda, H. Gu, E.G. Chiorean, M. Abu Zaid, M. Harrison, J. Pekny, P. Patrick, D. Zhang, M. Zhang*, D. Raftery*, “Exploring Metabolic Profile Differences between Colorectal Polyp Patients and Controls Using Seemingly Unrelated Regression”, J. Proteome Res., 14, 2492-2499, 2015. PMID: 25919433
2014:
W. Yao, H. Gu, J. Zhu, G. Barding, H. Cheng, B. Bao, L. Zhang*, A. Ding*, W. Li, “Integrated Plasma and Urine Metabolomics Coupled with HPLC/QTOF-MS and Chemometric Analysis on Potential Biomarkers in Liver Injury and Hepatoprotective Effects of Er-Zhi-Wan”, Anal. Bioanal. Chem., 406, 7367-7378, 2014. PMID: 25245419
J. Zhu, D. Djukovic, L. Deng, H. Gu, F. Himmati, E. Chiorean, D. Raftery*, “Colorectal Cancer Detection Using Targeted Serum Metabolic Profiling”, J. Proteome Res., 13, 4120-4130, 2014. PMID: 25126899
D. Dai, P. Karunadharma, Y. Chiao, N. Basisty, D. Crispin, E. Hsieh, T. Chen, H. Gu, D. Djukovic, D. Raftery, R. Beyer, M. Maccoss, P. Rabinovitch*, “Altered Proteome Turnover and Remodeling by Short-term Caloric Restriction or Rapamycin Rejuvenate the Aging Heart”, Aging Cell, 13, 529-539, 2014. PMCID: PMC4040127
2013:
H. Gu, A. N. Gowda, F. Carnevale Neto, M. Opp, D. Raftery*, “RAMSY: Ratio Analysis of Mass Spectrometry to Improve Compound Identification”, Anal. Chem., 85, 10771-10779, 2013. PMCID: PMC3867450
N. Xu, Z. Zhu, S. Yang, J. Wang, H. Gu*, H. Chen, “Direct Detection of Amino Acids Using Extractive Electrospray Ionization Tandem Mass Spectrometry”, Chin. J. Anal. Chem., 41, 523–528, 2013.
H. Baniasadi, A. N. Gowda, H. Gu, A. Zeng, S. Zhuang, N. Skill, M. Maluccio, D. Raftery*, “Targeted Metabolic Profiling of Hepatocellular Carcinoma and Hepatitis C using LC-MS/MS”, Electrophoresis, 34, 2910-2917, 2013. PMCID: PMC3826436
H. Zhang, H. Gu, F. Yan, N. Wang, Y. Wei, J. Xu, H. Chen*, “Direct Characterization of Bulk Samples by Internal Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 3, 2495, 2013. PMCID: PMC3750536
M. Li, J. Ding, H. Gu, Y. Zhang, S. Pan, N. Xu, H. Chen*, H. Li, “Facilitated Diffusion of Acetonitrile Revealed by Quantitative Breath Analysis Using Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 3, 1205, 2013. PMCID: PMC3564039
Y. Qi, H. Gu, Y. Song, X. Dong, A. Liu, Z. Lou, G. Fan, Y. Chai*, “Metabolomics Study of Resina Draconis on Myocardial Ischemia Rats Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry Combined with Pattern Recognition Methods and Metabolic Pathway Analysis”, Evid. Based Complement. Alternat. Med., 438680, 2013. PMCID: PMC3677627
F. Tayyari, A. N. Gowda, H. Gu, D. Raftery*, “15N-Cholamine-A Smart Isotope Tag for Combining NMR- and MS-Based Metabolite Profiling”, Anal. Chem., 85, 8715-8721, 2013. PMCID: PMC3803152
2012:
H. Gu, A. N. Gowda, D. Raftery*, "Metabolic Profiling: Are We en route to Better Diagnostic Tests for Cancer?", Future Oncol., 8, 1207-1210, 2012. PMID: 23130920
H. Gu, N. Xu, H. Chen*, “Direct Analysis of Biological Samples Using Extractive Electrospray Ionization Mass Spectrometry (EESI-MS)”, Anal. Bioanal. Chem., 403, 2145-2153, 2012. PMID: 22434271
H. Gu, Qi, Y. Qi, N. Xu, J. Ding, Y. An, H. Chen*, “Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry-Based Metabolomics for Cancer Diagnosis”, Chin. J. Anal. Chem., 40, 1933–1937, 2012.
C. Liu, X. Zhang, S. Xiao, B. Jia, S. Cui, J. Shi, N. Xu, X. Xie, H. Gu*, H. Chen, “Detection of Trace Levels of Lead in Aqueous Liquids Using Extractive Electrospray Ionization Tandem Mass Spectrometry”, Talanta, 98, 79-85, 2012. PMID: 22939131
Z. Zhu, J. Han, Y. Zhan, Y. Zhou, N. Xu, B. Zhang, H. Gu, H. Chen*, “Sensitive Ionization of Non-volatile Analytes Using Protein Solutions as Spray Liquid in Desorption Electrospray Ionization Mass Spectrometry”, Rapid Commun. Mass Spectrom., 26, 2770-2776, 2012. PMID: 23124668
2011:
H. Gu, Y. Huang, M. Filgueira, P. W. Carr*, “Effect of First Dimension Phase Selectivity in Online Comprehensive Two Dimensional Liquid Chromatography (LCxLC)”, J. Chrom. A., 1218, 6675-6687, 2011. PMCID: PMC3256932
H. Gu, Z. Pan, B. Xi, V. Asiago, B. Musselman, D. Raftery*, “Principal Component Directed Partial Least Squares Analysis for Combining NMR and MS Data in Metabolomics: Application to the Detection of Breast Cancer”, Anal. Chim. Acta, 686, 57-63, 2011. PMCID: PMC3040422
Y. Huang, H. Gu, M. Filgueira, P. W. Carr*, “An Experimental Study of Sampling Time Effects on the Resolving Power of Online Two-Dimensional HPLC”, J. Chrom. A., 1218, 2984-2994, 2011. PMCID: PMC3132878
B. Hu, S. Yang, M. Li, H. Gu, H. Chen*, “Direct Detection of Native Proteins in Biological Matrices Using Extractive Electrospray Ionization Mass Spectrometry”, Analyst, 136, 3599-3601, 2011. PMID: 21734987
2010:
H. Gu, Y. Huang, P. W. Carr*, “Peak Capacity Optimization in Comprehensive Two Dimensional Liquid Chromatography: A Practical Approach”, J. Chrom. A., 1218, 64-73, 2010. PMCID: PMC3034304
H. Gu, S. Yang, J. Li, B. Hu, H. Chen*, L. Zhang, Q. Fei, “Geometry Independent Neutral Desorption Device Sampling Explosives on Various Surfaces for Sensitive EESI-MS Detection”, Analyst, 135, 779-788, 2010. PMID: 20349542
H. Gu, B. Hu, J. Li, S. Yang, J. Han, H. Chen*, “Rapid Analysis of Aerosol Drugs Using Nano Extractive Electrospray Ionization Tandem Mass Spectrometry”, Analyst, 135, 1259-1267, 2010. PMID: 20498877
B. Hu, X. Peng, S. Yang, H. Gu, H. Chen*, Y. Huan, T. Zhang, X. Qiao, “Fast Quantitative Detection of Cocaine in Beverages Using Nanoextractive Electrospray Ionization Tandem Mass Spectrometry”, J. Am. Soc. Mass Spectrom., 21, 290-293, 2010. PMID: 19939702
2009:
H. Gu, Z. Pan, B. Xi, B. E. Hainline, N. Shanaiah, V. Asiago, A. N. Gowda, D. Raftery*, “1H NMR Metabolomics Study of Age Profiling in Children”, NMR Biomed., 22, 826-833, 2009. PMCID: PMC4009993
S. Yang, J. Han, Y. Huan, Y. Cui, X. Zhang, H. Chen, H. Gu*, “Desorption Electrospray Ionization Tandem Mass Spectrometry for Rapid Detection of 24 Carcinogenic Aromatic Amines in Textiles”, Anal. Chem., 81, 6070-6079, 2009.
J. Ding, H. Gu, S. Yang, M. Li, J. Li, H. Chen*, “Selective Detection of Diethylene Glycol in Toothpaste Products Using Neutral Desorption Reactive Extractive Electrospray Ionization Tandem Mass Spectrometry”, Anal. Chem., 81:8632-8638, 2009. PMID: 19761215
S. Yang, H. Chen*, Y. Yang, B. Hu, X. Zhang, Y. Zhou, L. Zhang, H. Gu, “Imaging Melamine in Egg Samples by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry”, Chin. J. Anal. Chem., 37, 315-318, 2009.
2008:
A. N. Gowda, S. Zhang, H. Gu, V. Asiago, N. Shanaiah, D. Raftery*, "Metabolomics-Based Methods for Early Disease Diagnostics: A Review", Expert Rev. Mol. Diagnos., 8, 617-33, 2008. PMCID: PMC3890417
2007:
H. Gu, Z. Pan, C. Duda, D. Mann, C. Kissinger, C. Rohde, D. Raftery*, “1H NMR Study of the Effects of Sample Contamination in the Metabolomics Analysis of Mouse Urine”, J. Pharm. Biomed. Anal., 45, 134-140, 2007. PMID: 17707608
H. Gu, H. Chen, Z. Pan, A. U. Jackson, N. Talaty, B. Xi, C. Kissinger, C. Duda, D. Mann, D. Raftery*, R. G. Cooks*, “Monitoring Diet Effects from Biofluids and Their Implications for Metabolomics Studies”, Anal. Chem., 79, 89-97, 2007. PMID: 17194125
H. Chen, Y. Sun, A. Wortmann, H. Gu, R. Zenobi*, “Differentiation of Maturity and Quality of Fruit Using Noninvasive Extractive Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry”, Anal. Chem., 79, 1447-1455, 2007. PMID: 17297943
Z. Pan, H. Gu, N. Talaty, H. Chen, B. E. Hainline, R. G. Cooks*, D. Raftery*, “Principal Component Analysis of Urine Metabolites Detected by NMR and DESI-MS in Patients with Inborn Errors of Metabolism”, Anal. Bioanal. Chem., 387, 539-549, 2007. PMID: 16821030
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