Publications

2021:

  1. G. Qi, Y. Mi, X. Shi, H. Gu, R.D. Brinton, F. Yin "ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism" J. Cell Reports, 34, 108572 PMID: 31969828

  2. A. J. Basile, A. E. Mohr, P. Jasbi‡, H. Gu, P. Deviche, and K. L. Sweazea*, “A four-week high fat diet does not alter plasma glucose or metabolic physiology in wild-caught mourning doves (Zenaida macroura)”, Comp. Biochem. Physiol. A. Mol. Integr. Physiol., 251, 110820, 2021. PMID: 33053437

  3. C. Zheng, G A Nagana Gowda, D. Raftery, M. Neuhouser, L. Tinke, R. Prentice, S. Beresford, Y. Zhang, L. Bettche, R. Pepin, D. Djukovic, H. Gu, G. Barding Jr, X. Song, J. Lampe "Evaluation of potential metabolomic-based biomarkers of protein, carbohydrate and fat intakes using a controlled feeding study" European Journal of Nutrition, Online ahead of print, PMID: 33991228

  4. Y. Wei, P. Jasbi, X. Shi, C. Turner, J. Hrovat, L. Liu, Y. Rabena, P. Porter, H. Gu "Early Breast Cancer Detection Using Untargeted and Targeted Metabolomics" Journal of Proteome Research, Online ahead of print, PMID: 34033488

  5. H. Gu, P. Jasbi, J. Patterson, Y. Jin "Enhanced Detection of Short-Chain Fatty Acids Using Gas Chromatography Mass Spectrometry" Current Protocols, 1, e177., PMID: Pending doi: 10.1002/cpz1.177

  6. P. Jasbi, X. Shi, P Chu, N. Elliott, H. Hudson, D. Jones, G. Serrano, B. Chow, T. Beach, L. Liu, G. Jentarra, H. Gu. "Metabolic profiling of neocortical tissue discriminates Alzheimer’s disease from mild cognitive impairment, high pathology controls, and normal controls." Journal of Proteome Research, ASAP PMID: Pending

2020:

1. Z. Dvořák, F. Kopp, C. M. Costello, J. S. Kemp, H. Li, A. Vrzalová, M. Štěpánková, I. Bartoňková, E. Jiskrová, K. Poulíková, [...], H. Gu, [...], S. Mani,* "Targeting the pregnane X receptor using microbial metabolite mimicry," EMBO Mol. Med., 12: e11621, PMID: 32153125

2. L. Deng, F. Guo, K. Cheng, J. Zhu, H. Gu, D. Raftery,* J. Dong,* "Identifying Significant Metabolic Pathways Using Multi-Block Partial Least-Squares Analysis," J. of Proteome Research, 19, 5, 1965-1974, PMID: 32174118

3. E. Quarles, N. Basisty, Y.A. Chaio, G. Merrihew, H. Gu, M.T. Sweetwyne, J. Fredrickson, N.H. Nguyen, M. Razumova, K. Kooiker, F. Moussavi-Harami, M. Reginer, C. Quarles, M. MacCoss, P.S. Rabinovitch,* "Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment," J. Aging Cell, 19(2):e13086, PMID: 31823466

4. J.L. Mangal, S. Inamdar, Y. Yang, X. Shi, M. Wankhede, H. Gu, K. Rege, M.D. Green, M. Curtis and A. Acharya,* "Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism," J. of Materials Chemistry B, Jun 24;8(24):5195-5203. PMID: 32427266

5. R. Eghlimi, X. Shi, J. Hrovat, B. Xi, H. Gu,* "Triple Negative Breast Cancer Detection Using LC-MS/MS Lipidomic Profiling," J. of Proteome Research, 19(6):2367-2378. PMID: 32397718

6. J.J. Lim, X. Li 2, H. Lehmler, D. Wang, H. Gu, J.Y. Cui,* "Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice," Toxicol Sci., kfaa090. PMID: 32544245

7. H. He, X. Shi, A. Lawrence, J. Hrovat, C. Turner, J.Y. Cui*, H. Gu,* "2,2',4,4'-tetrabromodiphenyl Ether (BDE-47) Induces Wide Metabolic Changes Including Attenuated Mitochondrial Function and Enhanced Glycolysis in PC12 Cells," Ecotoxicol. Environ. Saf., 201:110849. PMID: 32559690

8. X. Shi, B. Xi, P. Jasbi, C. Turner, Y. Jin, H. Gu,* "Comprehensive Isotopic Targeted Mass Spectrometry (CIT-MS): Reliable Metabolic Flux Analysis with Broad Coverage," Analytical Chemistry, 1;92(17):11728-11738 . PMID: 32697570

9. A. J. Basile, P. Jasbi‡, W. Clark, X. Shi‡, H. Gu, P. Deviche, and K. L. Sweazea*, “A four-week white bread diet does not alter plasma glucose concentrations, metabolic or vascular physiology in mourning doves, Zenaida macroura”, Comp. Biochem. Physiol. A. Mol. Integr. Physiol., 247, 110718, 2020. PMID: 32376459

10. H. Gu, X. Shi, P. Jasbi, J. Patterson. "Metabolomics Analysis of Viral Therapeutics." Methods Mol Biol. 2021;2225:179-197. PMID: 33108663.

11. M. Gomez, M. Dutta, A. Suvorov, X. Shi, H. Gu, S. Mani, J. Y. Cui. "Early life exposure to environmental contaminants (BDE-47, TBBPA, and BPS) produced persistent alterations in fecal microbiome in adult male mice" Toxicological Sciences, , kfaa161. PMID: 33078840


2019:

1. D. Gutierrez, A. Weinstock, V. Antharam, H. Gu, P. Jasbi, X. Shi, B. Dirks, R. Krajmalnik-Brown, J. Maldonado, J. Guinan, S. Thangamani, "Antibiotic-induced gut metabolome and microbiome alterations increase the susceptibility to Candida albicans colonization in the gastrointestinal tract," FEMS Microbiol. Ecol., pii: fiz187, 2019, PMID: 31769789

2. G. Kurgan, L. Kurgan, A. Schneider, M. Onyeabor, Y. Rodriguez-Sanchez, E. Taylor, R. Martinez, P. Carbonell, X. Shi, H. Gu., X. Wang*, "Identification of major malate export systems in an engineered malate-producing Escherichia coli aided by substrate similarity search," Appl. Microbiol. Biotechnol., 103(21-22):9001-9011, 2019, PMID: 31641813

3. R.L. Burr, H. Gu, K. Cain, D. Djukovic, X. Zhang, C. Han, N. Callan, D. Raftery, M. Heitkemper, "Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study," J. Neurogastroenterol. Motil., 25(4):551-562, 2019, PMID: 31587547

4. P. Jasbi, O. Baker, X. Shi, L. A. Gonzalez, S. Wang, S. Anderson, B. Xi, H. Gu* and C. S. Johnston*, "Daily red wine vinegar ingestion for eight weeks improves glucose homeostasis and affects the metabolome but does not reduce adiposity in adults," Food & Function, 10(11):7343-7355, 2019, PMID: 31647087.

5. X. Shi, S. Wang, P. Jasbi, C. Turner, J. Hrovat, Y. Wei, J. Liu, and H. Gu*, "Database Assisted Globally Optimized Targeted Mass Spectrometry (dGOT-MS): Broad and Reliable Metabolomics Analysis with Enhanced Identification", Anal. Chem., 91 (21), 13737-13745, 2019, PMID: 31556994

6. X. Wang, H. Gu, S.A. Palma-Duran, A. Fierro, P. Jasbi, X. Shi, W. Bresette, N. Tasevska*, "Influence of Storage Conditions and Preservatives on Metabolite Fingerprints in Urine", Metabolites, 9(10). pii: E203, 2019, PMID: 31569767

7. D. K. Scoville, C. Y. Li, D. Wang, J. L. Dempsey, D. Raftery, S. Mani, H. Gu* and J. Y. Cui*, "Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice", Drug Metab. Dispos., 47 (8), 928-940, 2019, PMID: 31123037

8. J. Dempsey, D. Wang, G. Siginir, Q. Fei, D. Raftery, H. Gu, J. Y. Cui*, “Pharmacological Activation of PXR and CAR Downregulates Distinct Bile Acid-Metabolizing Intestinal Bacteria and Alters Bile Acid Homeostasis”, Toxicol Sci., 168, 40-60, 2019. PMID: 30407581

9. P. Jasbi, N. M. Mitchell, X. Shi, T. E. Grys, Y. Wei, L. Liu, D. F. Lake, and H. Gu*, "Coccidioidomycosis Detection Using Targeted Plasma and Urine Metabolic Profiling." J. of Proteome Research, 18, 7, 2791-2802, 2019. PMID: 31244214

10. P. Jasbi, D. Wang, L. Cheng, Q. Fei, Y. Cui, L. Liu, Y. Wei, D. Raftery, H. Gu*, “Breast cancer detection using targeted plasma metabolomics”, J. Chromatogr B, 1105:26-37, 2019. PMID: 30562627

11. Q. Fei, D. Wang, P. Jasbi, P. Zhang, G. A. Nagana Gowda, D. Raftery, and H. Gu*, "Combining NMR and MS with Chemical Derivatization for Absolute Quantification with Reduced Matrix Effects", Analytical Chemistry, 91(6):4055-4062, 2019. PMID: 30801179

12. X. Zhang, X. Xie, B. Heckmann, A. Saarinen, H. Gu, R. Zechner, and J. Liu, "Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)", FASEB J., 33(5):6655-6666, 2019 PMID: 30802154

13. B. Zhua, H. Cao, G. Li, W. Du, G. Xu, J. Santo Domingo, H. Gu, N. Xu, S. Duan, J. Lu, "Biodiversity and dynamics of cyanobacterial communities during blooms in temperate lake (Harsha Lake, Ohio, USA)", J. Harmful Algae, 82, 9-18, 2019. PMID: 30928013

14. S. L. Navarro, A. Tarkhan, A. Shojaie, T. W. Randolph, H. Gu, D. Djukovic, K. J. Osterbauer, M. A. Hullar, M. Kratz, M. L. Neuhouser, P. D. Lampe, D. Raftery, J. W. Lampe, "Plasma metabolomics profiles suggest beneficial effects of a low–glycemic load dietary pattern on inflammation and energy metabolism", The American Journal of Clinical Nutrition, 110(4):984-992, 2019. PMID: 31432072

2018:

1. D. Wang, X. Sun, J. Yan, B. Ren, B. Cao, Q. Lu, Y. Liu, J. Zeng, N. Huang, Q. Xie, H. Gu*, J. Wang*, “Alterations of eicosanoids and related mediators in patients with schizophrenia”, J Psychiatr. Res., 102:168-178, 2018. PMID: 29674269

2. C. Li, J. L. Dempsey, D. Wang, S. Lee, K. M. Weigel, Q. Fei, D. K. Bhatt, B. Prasad, D. Raftery, H. Gu, J. Y. Cui*, “PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice”, Drug Metab. Dispos., 2018. PMID: 29769268

3. D. Du, H. Gu, D. Djukovic, L. Bettcher, M. Gong, W. Zheng, L. Hu, X. Zhang, R. Zhang, D. Wang, D. Raftery*, “Multiplatform Metabolomics Investigation of Antiadipogenic Effects on 3T3-L1 Adipocytes by a Potent Diarylheptanoid”, J. Proteome Res., 17, 2092-2101, 2018. PMID: 29688022

4. B. N. R. Ginos, S. L. Navarro, Y. Schwarz, H. Gu, D. Wang, T. W. Randolph, A. Shojaie, M. A. J. Hullar, P. D. Lampe, M. Kratz, M. L. Neuhouser, D. Raftery, J. W. Lampe, “Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study”, Metabolism, 83,197-204, 2018. PMCID: PMC5960615

5. R. J. Davis, M. Gönen, D. H. Margineantu, S. Handeli, J. Swanger, P. Hoellerbauer, P. J. Paddison, H. Gu, D. Raftery, J. E. Grim, D. M. Hockenbery, A. A. Margolin, B. E. Clurman, “Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism”, PNAS, 115, 5462-5467, 2018. PMID: 29735700

6. R. Li, S. Grimm, D. Mav, H. Gu, D. Djukovic, R. Shah, B. Merrick, D. Raftery, P. Wade*, “Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer”, Cell Rep., 624-637, 2018. PMCID: PMC5793878

7. G. A. N. Gowda, D. Djukovic, L. Bettcher, H. Gu, D. Raftery*, “NMR-Guided Mass Spectrometry for Absolute Quantitation of Human Blood Metabolites”, Anal. Chem., 90, 2001-2009, 2018. PMID: 29293320

8. J. Liu, Hanavan PD, Kras K, Ruiz YW, Castle EP, Lake DF, Chen X, O'Brien D, Luo H, Robertson KD, H. Gu*, Ho TH*, "Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines toward Enhanced Oxidative Phosphorylation", J. Proteome Res., 2018. PMID: 30406665

9. P. Lohavanichbutr, Y. Zhang, P. Wang, H. Gu, G. A. N. Gowda, D. Djukovic, M. Buas, D. Raftery, C. Chen*, “Salivary metabolite profiling distinguishes patients with oral cavity squamous cell carcinoma from normal controls”, PLoS One, e0204249, 2018. PMCID: PMC6147497

10. D. Shao, O. Villet, Z. Zhang, S. Choi, J. Yan, J. Ritterhoff, H. Gu, D. Djukovic, D. Christodoulou, S. Kolwicz, D. Raftery, R. Tian*, “Glucose promotes cell growth by suppressing branched-chain amino acid degradation”, Nat. Commun., 9, 2935, 2018. PMCID: PMC6062555

11. R. Centini, M. Tsang, T. Iwata, H. Park, J. Delrow, D. Margineantu, B. Iritani, H. Gu, H. Liggitt, J. Kang, L. Kang, D. Hockenbery, D. Raftery, B. Iritani*, “Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation”, PLoS One, e0197973, 2018. PMCID: PMC5999084

12. B. Roshanravan, L. Zelnick, D. Djucovic, H. Gu, J. Alvarez, T. Ziegler, J. Gamboa, K. Utzschneider, B. Kestenbaum, J. Himmelfarb, S. Kahn, D. Raftery, I. de Boer*, “Chronic kidney disease attenuates the plasma metabolome response to insulin”, JCI Insight, 3, e122219, 2018. PMCID: PMC6141172

13. Shuyun Liu, Meng Zhao, Yijie Zhou, Chengshi Wang, Yujia Yuan, Lan Li, W. Bresette, Younan Chen, Jingqiu Cheng, Yanrong Lu*, J. Liu*, "Resveratrol exerts dose-dependent anti-fibrotic or pro-fibrotic effects in kidneys: a potential risk to individuals with impaired kidney function", Phytomedicine, 2018. PHYMED 52801

14) D. Wang, S. Cheng, Q. Fei, H. Gu, D. Raftery, B. Cao, X. Sun, J. Yan, C. Zhang, J. Wang*, “Metabolic profiling identifies phospholipids as potential serum biomarkers for schizophrenia”, Psychiatry Res., 272, 18-29, 2018. PMID: 30579177

2017:

  1. C. Chen, G. A. N. Nagana, J. Zhu, L. Deng, H. Gu, E. G. Chiorean, M. Abu Zaid, M. Harrison, D. Zhang, M. Zhang*, D. Raftery*, “Altered metabolite levels and correlations in patients with colorectal cancer and polyps detected using seemingly unrelated regression analysis”, Metabolomics, 12, 125, 2017.

2. J. R. Chao, K. Knight, A. L. Engel, C. Jankowski, Y. Wang, M. A. Manson, H. Gu, D. Djukovic, D. Raftery, J. B. Hurley, J. Du*, “Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side”, J. Bio. Chem., 292, 12895-12905, 2017. PMCID: PMC5546030

3. F. Miles, S. Navarro, Y. Schwarz, H. Gu, D. Djukovic, T. Randolph, A. Shojaie, M. Kratz, M. Hullar, P. Lampe, M. Neuhouser, D. Raftery, J. Lampe*, “Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets”, Food Funct., 8, 3209-3218, 2017. PMID: 28808723

4. M. Buas, H. Gu, D. Djukovic, J. Zhu, L. Onstad, B. Reid, D. Raftery*, T. Vaughan*, “Candidate serum metabolite biomarkers for differentiating gastroesophageal reflux disease, Barrett's esophagus, and high-grade dysplasia/esophageal adenocarcinoma”, Metabolomics, 13, 23, 2017. PMCID: PMC5295138

5. H. Lu, H. Zhu*, T. Zhu, Y. Xiao, S. Xie, H. Gu, M. Cui, L. Luo, “Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 7, 5136, 2017. PMCID: PMC5506000.

6. T. Li, Z. Zhang, S. Kolwicz, L. Abell, N. Roe, M. Kim, B. Zhou, Y. Cao, J. Ritterhoff, H. Gu, D. Raftery, H. Sun, R. Tian*, “Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury”, Cell Metab., 25, 374-385, 2017. PMCID: PMC5301464.

7. J. Rabinowitz, A. Robitaille, Y. Wang, C. Ray, R. Thummel, H. Gu, D. Djukovic, D. Raftery, J. Berndt, R. Moon*, “Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish”, PNAS, 114, E717-E726, 2017. PMCID: PMC5293114.

2016:

  1. F. Carnevale Neto, A. C. Pilon, D. M. Selegato, R. T. Freire, H. Gu, D. Raftery, N. P. Lopes*, I. Castro-Gamboa*, “Dereplication of Natural Products Using GC-TOF Mass Spectrometry: Improved Metabolite Identification by Spectral Deconvolution Ratio Analysis”, Front. Mol. Biosci., 3, 59, 2016. PMCID: PMC5044510

2. H. Zhao, J. Shen, D. Djukovic, C. Daniel-MacDougall, H. Gu, X. Wu, W. H. Chow, “Metabolomics-identified metabolites associated with body mass index and prospective weight gain among Mexican American women”, Obes. Sci. & Pract., 2, 309-317, 2016. PMCID: PMC5043515

3. H. Gu, J. Du, P. A. Carroll, J. Zhu, F. Carnevale Neto, R. N. Eisenman, D. Raftery*, “Quantitative Method to Investigate the Balance between Metabolism and Proteome Biomass: Starting from Glycine”, Angew. Chem. Int. Ed., 55, 15656-15650, 2016. PMID: 27860107

4. B. Parent*, M. Seaton, R. Sood, H. Gu, D. Djukovic, D. Raftery, G. O'Keefe, “Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients”, JAMA Surg., 151, e160853, 2016. PMID: 27223119

5. L. Deng, H. Gu*, J. Zhu, G. A. Nagana Gowda, D. Djukovic, E. G. Chiorean, D. Raftery*, “Combining NMR and LC/MS Using Backward Variable Elimination: Metabolomics Analysis of Colorectal Cancer, Polyps, and Healthy Controls”, Anal. Chem., 88, 7975-7983, 2016. PMID: 27437783

6. M. Buas, H. Gu, D. Djukovic, J. Zhu, C. W. Drescher, N. Urban, D. Raftery, C. Li*, “Identification of Novel Candidate Plasma Metabolite Biomarkers for Distinguishing Serous Ovarian Carcinoma and Benign Serous Ovarian Tumors”, Gynecol. Oncol., 140, 138-144, 2016. PMID: 26521694

7. M. Heitkemper*, C. Han, M. Jarrett, H. Gu, D. Djukovic, R. Shulman, D. Raftery, W. Henderson, K. Cain, “Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)”, Biol. Res. Nurs., 18, 193-198, 2016. PMID: 26156003

8. J. Du, A. Rountree, W. M. Cleghorn, L. Contreras, K. J. Lindsay, M. Sadilek, H. Gu, D. Djukovic, D. Raftery, J. Satrústegui, M. Kanow, L. Chan, S. H. Tsang, I. R. Sweet, J. B. Hurley*, “Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina”, J. Bio. Chem., 291, 4698-4710, 2016. PMCID: PMC4813492

9. Y. Chiao, S. C. Kolwicz, N. Basisty, A. Gagnidze, J. Zhang, H. Gu, D. Djukovic, R. P. Beyer, D. Raftery, M. MacCoss, R. Tian, P. S. Rabinovitch*, “Rapamycin Transiently Induces Mitochondrial Remodeling to Reprogram Energy Metabolism in Old Hearts”, Aging, 8, 314-327, 2016. PMID: 26872208

10. S. Lim, C. Li, W. Xia, H. Lee, S. Chang, J. Shen, J. Hsu, D. Raftery, D. Djukovic, H. Gu, W. Chang, H. Chang, H. Wang, M. Chen, L. Huo, C. Chen, Y. Wu, A. Sahin, S. Hanash, G. Hortobagyi, M. Hung*, “EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape”, Cancer Res., 76, 1284-1296, 2016. PMCID: PMC4775355

2015:

  1. H. Gu*, P. Zhang, J. Zhu, D. Raftery*, “Globally Optimized Targeted Mass Spectrometry (GOT-MS): Reliable Metabolomics Analysis with Broad Coverage”, Anal, Chem., 87, 12355-12362, 2015. PMID: 26579731

  2. H. Sperber, J. Mathieu, Y. Wang, A. Ferreccio, J. Hesson, Z. Xu, K. A. Fischer, A. Devi, D. Detraux, H. Gu, S. L. Battle, M. Showalter, C. Valensisi, J. H. Bielas, N. G. Ericson, L. Margaretha, A. M. Robitaille, D. Margineantu, O. Fiehn, D. Hockenbery, C. A. Blau, D. Raftery, A. A. Margolin, R. D. Hawkins, R. T. Moon, C. B. Ware, H. Ruohola-Baker*, “The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition”, Nat. Cell Bio., 17, 1523-1535, 2015. PMCID: PMC4662931

  3. J. Zhu, D. Djukovic, L. Deng, H. Gu, F. Himmati, M. Abu Zaid, E. G. Chiorean, D. Raftery*, “Targeted serum metabolite profiling and sequential metabolite ratio analysis for colorectal cancer progression monitoring”, Anal. Bioanal. Chem., 407, 7857-7863, 2015. PMID: 26342311

  4. J. Wang, Q. Li, H. Gu, X. Guo, S. Yang, Z. Wang, “Direct Analysis of Micro Area on Tooth Surface by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry”, Chem. J. Chin. Univ., 36, 1067-1073, 2015.

  5. H. Gu*, J. Du, F. Carnevale Neto, P. Carroll, S. Turner, G. Chiorean, R. Eisenman, D. Raftery, “Metabolomics Method to Comprehensively Analyze Amino Acids in Different Domains”, Analyst, 140, 2726-2734, 2015. PMCID: PMC4380628

  6. P. Carroll, D. Diolaiti, L. McFerrin, H. Gu, D. Djukovic, J. Du, P. Cheng, S. Anderson, M. Ulrich, J. Hurley, D. Raftery, D. Ayer, R. Eisenman*, “Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis”, Cancer Cell, 27, 271-285, 2015. PMCID: PMC4326605

  7. N. Reyes, G. Banks, M. Tsang, D. Margineantu, H. Gu, D. Djukovic, J. Chan, M. Torres, H. Liggitt, D. Hirenallur-S, D. Hockenbery, D. Raftery, B. Iritani*, “Fnip1 Regulates Skeletal Muscle Fiber Type Specification, Fatigue Resistance, and Susceptibility to Muscular Dystrophy”, PNAS, 112, 424-429, 2015. PMCID: PMC4299192

  8. R. Sood, H. Gu, D. Djukovic, L. Deng, M. Ga, L. Muffley, D. Raftery, A. Hocking*, “Targeted Metabolic Profiling of Wounds in Diabetic and Nondiabetic Mice”, Wound Repair Regen., 23, 423-34, 2015. PMID: 25845676

  9. S. Barton, S. Navarro, M. Buas, Y. Schwarz, H. Gu, D. Djukovic, D. Raftery, M. Kratz, M. Neuhouser, J. Lampe*, “Targeted Plasma Metabolome Response to Variations in Dietary Glycemic Load in a Randomized, Controlled, Crossover Feeding Trial in Healthy Adults”, Food Funct., 2015. PMID: 26165375

  10. S. Pan, Y. Tian, M. Li, J. Zhao, L. Zhu, W. Zhang, H. Gu*, H. Wang, J. Shi, X. Fang, P. Li, H. Chen, “Quantitative Detection of Nitric Oxide in Exhaled Human Breath by Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 5, 8725, 2015. PMCID: PMC4348632

  11. C. Chen, L. Deng, S. Wei, G.A.N. Gowda, H. Gu, E.G. Chiorean, M. Abu Zaid, M. Harrison, J. Pekny, P. Patrick, D. Zhang, M. Zhang*, D. Raftery*, “Exploring Metabolic Profile Differences between Colorectal Polyp Patients and Controls Using Seemingly Unrelated Regression”, J. Proteome Res., 14, 2492-2499, 2015. PMID: 25919433

2014:

  1. W. Yao, H. Gu, J. Zhu, G. Barding, H. Cheng, B. Bao, L. Zhang*, A. Ding*, W. Li, “Integrated Plasma and Urine Metabolomics Coupled with HPLC/QTOF-MS and Chemometric Analysis on Potential Biomarkers in Liver Injury and Hepatoprotective Effects of Er-Zhi-Wan”, Anal. Bioanal. Chem., 406, 7367-7378, 2014. PMID: 25245419

  2. J. Zhu, D. Djukovic, L. Deng, H. Gu, F. Himmati, E. Chiorean, D. Raftery*, “Colorectal Cancer Detection Using Targeted Serum Metabolic Profiling”, J. Proteome Res., 13, 4120-4130, 2014. PMID: 25126899

  3. D. Dai, P. Karunadharma, Y. Chiao, N. Basisty, D. Crispin, E. Hsieh, T. Chen, H. Gu, D. Djukovic, D. Raftery, R. Beyer, M. Maccoss, P. Rabinovitch*, “Altered Proteome Turnover and Remodeling by Short-term Caloric Restriction or Rapamycin Rejuvenate the Aging Heart”, Aging Cell, 13, 529-539, 2014. PMCID: PMC4040127

2013:

  1. H. Gu, A. N. Gowda, F. Carnevale Neto, M. Opp, D. Raftery*, “RAMSY: Ratio Analysis of Mass Spectrometry to Improve Compound Identification”, Anal. Chem., 85, 10771-10779, 2013. PMCID: PMC3867450

  2. N. Xu, Z. Zhu, S. Yang, J. Wang, H. Gu*, H. Chen, “Direct Detection of Amino Acids Using Extractive Electrospray Ionization Tandem Mass Spectrometry”, Chin. J. Anal. Chem., 41, 523–528, 2013.

  3. H. Baniasadi, A. N. Gowda, H. Gu, A. Zeng, S. Zhuang, N. Skill, M. Maluccio, D. Raftery*, “Targeted Metabolic Profiling of Hepatocellular Carcinoma and Hepatitis C using LC-MS/MS”, Electrophoresis, 34, 2910-2917, 2013. PMCID: PMC3826436

  4. H. Zhang, H. Gu, F. Yan, N. Wang, Y. Wei, J. Xu, H. Chen*, “Direct Characterization of Bulk Samples by Internal Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 3, 2495, 2013. PMCID: PMC3750536

  5. M. Li, J. Ding, H. Gu, Y. Zhang, S. Pan, N. Xu, H. Chen*, H. Li, “Facilitated Diffusion of Acetonitrile Revealed by Quantitative Breath Analysis Using Extractive Electrospray Ionization Mass Spectrometry”, Sci. Reports, 3, 1205, 2013. PMCID: PMC3564039

  6. Y. Qi, H. Gu, Y. Song, X. Dong, A. Liu, Z. Lou, G. Fan, Y. Chai*, “Metabolomics Study of Resina Draconis on Myocardial Ischemia Rats Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry Combined with Pattern Recognition Methods and Metabolic Pathway Analysis”, Evid. Based Complement. Alternat. Med., 438680, 2013. PMCID: PMC3677627

  7. F. Tayyari, A. N. Gowda, H. Gu, D. Raftery*, “15N-Cholamine-A Smart Isotope Tag for Combining NMR- and MS-Based Metabolite Profiling”, Anal. Chem., 85, 8715-8721, 2013. PMCID: PMC3803152

2012:

  1. H. Gu, A. N. Gowda, D. Raftery*, "Metabolic Profiling: Are We en route to Better Diagnostic Tests for Cancer?", Future Oncol., 8, 1207-1210, 2012. PMID: 23130920

  2. H. Gu, N. Xu, H. Chen*, “Direct Analysis of Biological Samples Using Extractive Electrospray Ionization Mass Spectrometry (EESI-MS)”, Anal. Bioanal. Chem., 403, 2145-2153, 2012. PMID: 22434271

  3. H. Gu, Qi, Y. Qi, N. Xu, J. Ding, Y. An, H. Chen*, “Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry-Based Metabolomics for Cancer Diagnosis”, Chin. J. Anal. Chem., 40, 1933–1937, 2012.

  4. C. Liu, X. Zhang, S. Xiao, B. Jia, S. Cui, J. Shi, N. Xu, X. Xie, H. Gu*, H. Chen, “Detection of Trace Levels of Lead in Aqueous Liquids Using Extractive Electrospray Ionization Tandem Mass Spectrometry”, Talanta, 98, 79-85, 2012. PMID: 22939131

  5. Z. Zhu, J. Han, Y. Zhan, Y. Zhou, N. Xu, B. Zhang, H. Gu, H. Chen*, “Sensitive Ionization of Non-volatile Analytes Using Protein Solutions as Spray Liquid in Desorption Electrospray Ionization Mass Spectrometry”, Rapid Commun. Mass Spectrom., 26, 2770-2776, 2012. PMID: 23124668

2011:

  1. H. Gu, Y. Huang, M. Filgueira, P. W. Carr*, “Effect of First Dimension Phase Selectivity in Online Comprehensive Two Dimensional Liquid Chromatography (LCxLC)”, J. Chrom. A., 1218, 6675-6687, 2011. PMCID: PMC3256932

  2. H. Gu, Z. Pan, B. Xi, V. Asiago, B. Musselman, D. Raftery*, “Principal Component Directed Partial Least Squares Analysis for Combining NMR and MS Data in Metabolomics: Application to the Detection of Breast Cancer”, Anal. Chim. Acta, 686, 57-63, 2011. PMCID: PMC3040422

  3. Y. Huang, H. Gu, M. Filgueira, P. W. Carr*, “An Experimental Study of Sampling Time Effects on the Resolving Power of Online Two-Dimensional HPLC”, J. Chrom. A., 1218, 2984-2994, 2011. PMCID: PMC3132878

  4. B. Hu, S. Yang, M. Li, H. Gu, H. Chen*, “Direct Detection of Native Proteins in Biological Matrices Using Extractive Electrospray Ionization Mass Spectrometry”, Analyst, 136, 3599-3601, 2011. PMID: 21734987

2010:

  1. H. Gu, Y. Huang, P. W. Carr*, “Peak Capacity Optimization in Comprehensive Two Dimensional Liquid Chromatography: A Practical Approach”, J. Chrom. A., 1218, 64-73, 2010. PMCID: PMC3034304

  2. H. Gu, S. Yang, J. Li, B. Hu, H. Chen*, L. Zhang, Q. Fei, “Geometry Independent Neutral Desorption Device Sampling Explosives on Various Surfaces for Sensitive EESI-MS Detection”, Analyst, 135, 779-788, 2010. PMID: 20349542

  3. H. Gu, B. Hu, J. Li, S. Yang, J. Han, H. Chen*, “Rapid Analysis of Aerosol Drugs Using Nano Extractive Electrospray Ionization Tandem Mass Spectrometry”, Analyst, 135, 1259-1267, 2010. PMID: 20498877

  4. B. Hu, X. Peng, S. Yang, H. Gu, H. Chen*, Y. Huan, T. Zhang, X. Qiao, “Fast Quantitative Detection of Cocaine in Beverages Using Nanoextractive Electrospray Ionization Tandem Mass Spectrometry”, J. Am. Soc. Mass Spectrom., 21, 290-293, 2010. PMID: 19939702

2009:

  1. H. Gu, Z. Pan, B. Xi, B. E. Hainline, N. Shanaiah, V. Asiago, A. N. Gowda, D. Raftery*, “1H NMR Metabolomics Study of Age Profiling in Children”, NMR Biomed., 22, 826-833, 2009. PMCID: PMC4009993

  2. S. Yang, J. Han, Y. Huan, Y. Cui, X. Zhang, H. Chen, H. Gu*, “Desorption Electrospray Ionization Tandem Mass Spectrometry for Rapid Detection of 24 Carcinogenic Aromatic Amines in Textiles”, Anal. Chem., 81, 6070-6079, 2009.

  3. J. Ding, H. Gu, S. Yang, M. Li, J. Li, H. Chen*, “Selective Detection of Diethylene Glycol in Toothpaste Products Using Neutral Desorption Reactive Extractive Electrospray Ionization Tandem Mass Spectrometry”, Anal. Chem., 81:8632-8638, 2009. PMID: 19761215

  4. S. Yang, H. Chen*, Y. Yang, B. Hu, X. Zhang, Y. Zhou, L. Zhang, H. Gu, “Imaging Melamine in Egg Samples by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry”, Chin. J. Anal. Chem., 37, 315-318, 2009.

2008:

  1. A. N. Gowda, S. Zhang, H. Gu, V. Asiago, N. Shanaiah, D. Raftery*, "Metabolomics-Based Methods for Early Disease Diagnostics: A Review", Expert Rev. Mol. Diagnos., 8, 617-33, 2008. PMCID: PMC3890417

2007:

  1. H. Gu, Z. Pan, C. Duda, D. Mann, C. Kissinger, C. Rohde, D. Raftery*, “1H NMR Study of the Effects of Sample Contamination in the Metabolomics Analysis of Mouse Urine”, J. Pharm. Biomed. Anal., 45, 134-140, 2007. PMID: 17707608

  2. H. Gu, H. Chen, Z. Pan, A. U. Jackson, N. Talaty, B. Xi, C. Kissinger, C. Duda, D. Mann, D. Raftery*, R. G. Cooks*, “Monitoring Diet Effects from Biofluids and Their Implications for Metabolomics Studies”, Anal. Chem., 79, 89-97, 2007. PMID: 17194125

  3. H. Chen, Y. Sun, A. Wortmann, H. Gu, R. Zenobi*, “Differentiation of Maturity and Quality of Fruit Using Noninvasive Extractive Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry”, Anal. Chem., 79, 1447-1455, 2007. PMID: 17297943

  4. Z. Pan, H. Gu, N. Talaty, H. Chen, B. E. Hainline, R. G. Cooks*, D. Raftery*, “Principal Component Analysis of Urine Metabolites Detected by NMR and DESI-MS in Patients with Inborn Errors of Metabolism”, Anal. Bioanal. Chem., 387, 539-549, 2007. PMID: 16821030