LABORATORIO DE ESTRUCTURA Y FUNCIÓN CELULAR

YAPUR, un alimento funcional para los síntomas del resfrío - INNOVA Región 2024, CORFO.

Impacto de la terapia de reemplazo hormonal con estrógenos en la morbimortalidad por COVID-19 en mujeres peri y postmenopáusicas - PIEM-UV, 2024, Universidad de Valparaíso.

Impacto de la infección materna por SARS-CoV-2 en el neurodesarrollo infantil - PIEM-UV, 2024, Universidad de Valparaíso.

Constitución y uso del Consorcio Europeo-Latinoamericano para la erradicación del cáncer de vesícula biliar prevenible - EULAT Eradicate GBC - H2020, European Commission, 2023, University of Heidelberg.

Receptores sensitivos en uretra masculina; efecto de los estrógenos - PIEM-UV, 2023, Universidad de Valparaíso.

Caracterización clínica de embarazadas SAR-CoV-2 positivo y sus recién nacidos - SOCHIPE, 2023, Universidad de Valparaíso.

Escalamiento del sistema productivo de células madre mesenquimales para medicina regenerativa - CORFO Innovar, 2023, Medicel.

Factores de riesgo de mortalidad de pacientes COVID-19 hospitalizados - SSVQ, 2022, Universidad de Valparaíso.

Identificación retrospectiva de factores de riesgo de displasia y cáncer de vesícula biliar antes de la colecistectomía preventiva - SSVSA, 2021, Universidad de Valparaíso.

Optimización de criterios de diagnósticos histopatológicos del cáncer para el mejoramiento del rendimiento pronóstico - SSVSA, 2021, Universidad de Valparaíso.

Lápiz v/s Jeringa de Insulina: Costo-efectividad en diabéticos vulnerables - SSVQ, 2019, Universidad de Valparaíso.

Protocolo de interoperatividad para I+D - UEC, Universidad de Valparaíso.

Estrogen metabolites and its significance in human ovarian physiology and pathophysiology - FONDECYT 1140693, 2015, Universidad de Chile.

Modulation of TRP activity by estrogens: Protective mechanism in response to oxidative stress - FONDECYT 11100047, 2010, Universidad de Valparaíso.

Voltage Sensor of Ion Channels: From Structure to Function - ANILLO - ACT-1104, 2013, Universidad de Valparaíso.

Biomarkers and Cell Replacement Therapy at Early Parkinson’s Disease - ECOS-CONICYT, 2013, Universidad de Valparaíso.

Astaxantina como agente anti-envejecimiento cerebral - CORFO INNOVA, 2014, Universidad de Valparaíso.

Micaela Medrano, Claudio Cordova, Belén Rodriguez, Nicolás Simonelli, Pablo Olivero, Analía Graciela Abraham, KEFIRAN in vitro biological activity on enterocytes and mesodermal origin cell lines: Focus on adenocarcinoma cells HT29, Bioactive Carbohydrates and Dietary Fibre, Volume 32, 2024, 100457,DOI https://doi.org/10.1016/j.bcdf.2024.100457.

Serón, C., Olivero, P., Flores, N., Cruzat, B., Ahumada, F., Gueyffier, F., & Marchant, I. (2023). Diabetes, periodontitis, and cardiovascular disease: towards equity in diabetes care. Frontiers in public health, 11, 1270557. https://doi.org/10.3389/fpubh.2023.1270557

Cordova, C., Muñoz, R., Olivares, R., Minonzio, J. G., Lozano, C., Gonzalez, P., Marchant, I., González-Arriagada, W., & Olivero, P. (2022). HER2 classification in breast cancer cells: A new explainable machine learning application for immunohistochemistry. Oncology letters, 25(2), 44. https://doi.org/10.3892/ol.2022.13630

Marchant, I. C., Chabert, S., Martínez-Pinto, J., Sotomayor-Zárate, R., Ramírez-Barrantes, R., Acevedo, L., Córdova, C., & Olivero, P. (2022). Estrogen, Cognitive Performance, and Functional Imaging Studies: What Are We Missing About Neuroprotection?. Frontiers in cellular neuroscience, 16, 866122. https://doi.org/10.3389/fncel.2022.866122

Marchant, I., Stojanova, J., Acevedo, L., & Olivero, P. (2022). Estrogen rapid effects: a window of opportunity for the aging brain?. Neural regeneration research, 17(8), 1629–1632. https://doi.org/10.4103/1673-5374.332121

Córdova, C., Lozano, C., Rodríguez, B., Marchant, I., Zúñiga, R., Ochova, P., Olivero, P., & González-Arriagada, W. A. (2021). Optogenetic control of cancer cell survival in ChR2-transfected HeLa cells. International journal of experimental pathology, 102(6), 242–248. https://doi.org/10.1111/iep.12426

Ramírez-Barrantes, R., Carvajal-Zamorano, K., Rodriguez, B., Cordova, C., Lozano, C., Simon, F., Díaz, P., Muñoz, P., Marchant, I., Latorre, R., Castillo, K., & Olivero, P. (2020). TRPV1-Estradiol Stereospecific Relationship Underlies Cell Survival in Oxidative Cell Death. Frontiers in physiology, 11, 444. https://doi.org/10.3389/fphys.2020.00444

Domingueti, C. B., Janini, J. B., Paranaíba, L. M., Lozano-Burgos, C., Olivero, P., & González-Arriagada, W. A. (2019). Prognostic value of immunoexpression of CCR4, CCR5, CCR7 and CXCR4 in squamous cell carcinoma of tongue and floor of the mouth. Medicina oral, patologia oral y cirugia bucal, 24(3), e354–e363. https://doi.org/10.4317/medoral.22904

Ramírez-Barrantes, R., Córdova, C., Gatica, S., Rodriguez, B., Lozano, C., Marchant, I., Echeverria, C., Simon, F., & Olivero, P. (2018). Transient Receptor Potential Vanilloid 1 Expression Mediates Capsaicin-Induced Cell Death. Frontiers in physiology, 9, 682. https://doi.org/10.3389/fphys.2018.00682

Lozano, C., Córdova, C., Marchant, I., Zúñiga, R., Ochova, P., Ramírez-Barrantes, R., González-Arriagada, W. A., Rodriguez, B., & Olivero, P. (2018). Intracellular aggregated TRPV1 is associated with lower survival in breast cancer patients. Breast cancer (Dove Medical Press), 10, 161–168. https://doi.org/10.2147/BCTT.S170208

Olivero, P., Lozano, C., Sotomayor-Zárate, R., Meza-Concha, N., Arancibia, M., Córdova, C., González-Arriagada, W., Ramírez-Barrantes, R., & Marchant, I. (2018). Proteostasis and Mitochondrial Role on Psychiatric and Neurodegenerative Disorders: Current Perspectives. Neural plasticity, 2018, 6798712. https://doi.org/10.1155/2018/6798712

González-Arriagada, W. A., Olivero, P., Rodríguez, B., Lozano-Burgos, C., de Oliveira, C. E., & Coletta, R. D. (2018). Clinicopathological significance of miR-26, miR-107, miR-125b, and miR-203 in head and neck carcinomas. Oral diseases, 24(6), 930–939. https://doi.org/10.1111/odi.12872

Ramírez-Barrantes, R., Marchant, I., & Olivero, P. (2016). TRPV1 may increase the effectiveness of estrogen therapy on neuroprotection and neuroregeneration. Neural regeneration research, 11(8), 1204–1207. https://doi.org/10.4103/1673-5374.189162

Ramírez-Barrantes, R., Cordova, C., Poblete, H., Muñoz, P., Marchant, I., Wianny, F., & Olivero, P. (2016). Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity. Neural plasticity, 2016, 1568145. https://doi.org/10.1155/2016/1568145

García, I. E., Maripillán, J., Jara, O., Ceriani, R., Palacios-Muñoz, A., Ramachandran, J., Olivero, P., Perez-Acle, T., González, C., Sáez, J. C., Contreras, J. E., & Martínez, A. D. (2015). Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43. The Journal of investigative dermatology, 135(5), 1338–1347. https://doi.org/10.1038/jid.2015.20

Poblete, H., Oyarzún, I., Olivero, P., Comer, J., Zuñiga, M., Sepulveda, R. V., Báez-Nieto, D., González Leon, C., González-Nilo, F., & Latorre, R. (2015). Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels. The Journal of biological chemistry, 290(4), 2086–2098. https://doi.org/10.1074/jbc.M114.613620

Ibacache-Quiroga, C., Ojeda, J., Espinoza-Vergara, G., Olivero, P., Cuellar, M., & Dinamarca, M. A. (2013). The hydrocarbon-degrading marine bacterium Cobetia sp. strain MM1IDA2H-1 produces a biosurfactant that interferes with quorum sensing of fish pathogens by signal hijacking. Microbial biotechnology, 6(4), 394–405. https://doi.org/10.1111/1751-7915.12016

Madrid, E., Reyes, J. G., Hernández, B., García, J. M., San Martín, S., Olivero, P., Crespo, P. V., & Párraga, M. (2013). Effect of normobaric hypoxia on the testis in a murine model. Andrologia, 45(5), 332–338. https://doi.org/10.1111/and.12019

Revista de la Construcción vol.10 no.2 Santiago set. 2011

Simon, F., Leiva-Salcedo, E., Armisén, R., Riveros, A., Cerda, O., Varela, D., Eguiguren, A. L., Olivero, P., & Stutzin, A. (2010). Hydrogen peroxide removes TRPM4 current desensitization conferring increased vulnerability to necrotic cell death. The Journal of biological chemistry, 285(48), 37150–37158. https://doi.org/10.1074/jbc.M110.155390

Olivero, P., Leiva-Salcedo, E., Devoto, L., & Stutzin, A. (2008). Activation of Cl- channels by human chorionic gonadotropin in luteinized granulosa cells of the human ovary modulates progesterone biosynthesis. Endocrinology, 149(9), 4680–4687. https://doi.org/10.1210/en.2008-0303

Varela, D., Simon, F., Olivero, P., Armisén, R., Leiva-Salcedo, E., Jørgensen, F., Sala, F., & Stutzin, A. (2007). Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 20(6), 773–780. https://doi.org/10.1159/000110437 Copy

Olivero, P., & Stutzin, A. (2004). Calcium modulates osmosensitive taurine efflux in HeLa cells. Neurochemical research, 29(1), 169–176. https://doi.org/10.1023/b:nere.0000010446.50158.8d

Hermoso, M., Olivero, P., Torres, R., Riveros, A., Quest, A. F., & Stutzin, A. (2004). Cell volume regulation in response to hypotonicity is impaired in HeLa cells expressing a protein kinase Calpha mutant lacking kinase activity. The Journal of biological chemistry, 279(17), 17681–17689. https://doi.org/10.1074/jbc.M304506200