Sarah Cobey, PhD
Assistant Professor, Ecology & Evolution
Keynote Speaker: University of Chicago
Email: cobey@uchicago.edu
Phone: (617)756-7204 (c)
Research interests: The coevolution of hosts and pathogens. I use computational and mathematical tools to test hypotheses and to advance theory.
Current projects: My past work has focused on the evolutionary consequences of immune-mediated competition between different pathogen strains, especially in the context of influenza. More recently, my focus has expanded to include the related dynamics of the host immune response. I am investigating the evolution of antibody repertoires within hosts over time, in particular to identify the roles of infection history, chance, and vaccination in generating the diversity of immune responses. This work involves linking epidemiological and immunological observations of B cells (including experimental data from animal models), and to connect them to the antigenic and genetic evolution of influenza viruses.
System of Study: