Panagiotis Arapitsas
Short Bio
Short Bio
Panagiotis got his degree in Oenology - Food Technology in 2002 from Athens Technological University of Applied Sciences and later continued his studies at the University of Florence where he obtained a master in Methods of Synthesis in Organic Chemistry in 2004 and a PhD in Polyphenols Chemistry and Food Quality in 2008. During that period, his research activity was divided in laboratories of Analytical Chemistry, Organic Synthesis, Electrochemistry, Microbiology and wineries.In 2010 he joined the Food Quality group of Fondazione Edmund Mach where his activity focused in Food and Wine Metabolomics. In particular, his object is to establish methodologies for investigating fruit and wine metabolomes, by developing analytical protocols mainly with LC-MS techniques, data treatment and biomarker identification and hypotheses validation. He teaches at the Universities of Trento (Italy), West Attika (Greece) and Nova Gorica (Slovenia).
keywords: wine, grape, metabolomics, chromatography, mass spectrometry, polyphenols, anthocyanins, tannins, sulfonations, food analytical chemistry, green chemistry, organic synthesis, enology.
Timeline
Timeline
June 2022
New public study on the repository of Metabolights: MTBLS2401: Investigation of Brazilian grape juice metabolomic profile changes caused by methyl jasmonate pre-harvest treatment. linkJune 2022
New publication on Brazilian grape juice metabolomic profile changes caused by methyl jasmonate pre-harvest treatment. linkApril 2022
Presentation on the Enoforum 2022 in Spain about wine shelf life. linkFebruary 2022
New study on MetaboLights with the data and metadata about the quality of Chilean Cabernet Sauvignon. linkFebruary 2022
Italian scientific qualification in Pharmaceutical, toxicological, nutraceutical and food chemistry and technology, Sector 03/D1 (2nd level) 2022-2031January 2022
New affiliation as member of the Metabolomics Quality Assurance & Quality Control Consortium (mQACC), and it's Best Practices Working Group.December 2021
New publication, in collaboration with the Center for Research and Innovation of Viña Concha y Toro (Chile), on the metabolome of Chilean Cabernet Sauvignon and it's quality. linkNovember 2021
Panagiotis Arapitsas is between the top 2% scientists for 2020, according to the "August 2021 data-update for "Updated science-wide author databases of standardized citation indicators". Total rank position: 86127, food chemistry rank position 553 linkNovember 2021
New publication on Grapevine and Wine Metabolomics-Based Guidelines for FAIR Data and Metadata Management, in collaboration with 11 institutes from 6 countries (Italy, Greece, Spain, France, Portugal, Germany) and under the CostAction Integrape. linkOctober 2021
Local organizer on the MetaboOpen 2021 Virtual Training School on data and metadata management according to the FAIR guidelines. The school took place on Zoom from 4 to 6 October 2021, and was supported by the Cost Action Integrape. linkSeptember 2021
New publication in Modeling grape taste and mouthfeel from chemical composition, in collaboration with Instituto de Ciencias de la Vid y del Vino (ICVV) (Universidad de La Rioja-CSIC-Gobierno de La Rioja) and University of Zaragoza. linkJuly 2021
Alternated member of the the Board Committee 2021 of “Groupe Polyphénols” . link.June 2021
Participation to the virtual conference Macrowine 2021, as a member of the organize committee and chairperson, and with an flash talk and four posters. link.June 2021
Participation to the cost action Integrape annul (virtual) meeting, with a presentation made by Stefania Savoi link.June 2021
Seminars about how to manage Astringency in wines at the University of West Attika: Slideshare link for both parts: link.May 2021
New publication in Nutrients entitled "The Metabolomic-Gut-Clinical Axis of Mankai Plant-Derived Dietary Polyphenols". link.May 2021
Release of the guidelines on "How to submit metabolomic data to MetaboLights" on the website of the cost action Intergrape. link.May 2021
New publication in Metabolites (Grape and Wine Metabolome Analysis) about cluster thinning and vineyard site effect on wine (base and sparkling) metabolome link.April 2021
Seminars about Sparkling wines at the University of West Attika: Slideshare link for both part: link.April 2021
Seminars about wine metabolome at the University of West Attika: Slideshare link of the two parts: 1st part and 2nd part.March 2021
New publication in Frontiers Plant Science about the flavonoid accumulation in Cistus creticus subsp. creticus during the fruit development, using gene and metabolite analysis. linkMarch 2021
New publication in Food Research International about the Diversity of Italian red wines according to their enological parameters, color, and phenolic indices. The study was funded from the MIUR project N. 20157RN44Y. linkFebruary 2021
New publication in Molecules about the Proanthocyanidins mean Degree of Polymerization protocol in wine, and the characterization of Sagrantino di Montefalco and Brunello di Montalcino wines. linkDecember 2020
A Special Issue is lunched in Metabolites about “Grape and wine metabolome analysis”, that will be dedicated to the recent advancements in grape and wine metabolome analysis. The official submission deadline is 30 September 2021. linkNovember 2020
e-Seminar on Food Metabolomics at the Master students of Food Science of the Agricultural University of Athens, Greece (in Greek). linkOctober 2020
New publication in Foods entitled: Exploring Olfactory–Oral Cross-Modal Interactions through Sensory and Chemical Characteristics of Italian Red Wines. This work was made by the D:Wines consortium and funded by the by the MIUR project N. 20157RN44Y. 77 Italian red whole wines from 10 varieties, and corresponding deodorized wines, were evaluated by sensory descriptive assessment. In the absence of volatiles, correlation coefficients between sensory and chemical parameters mostly increased. linkOctober 2020
New publication in Journal of Argicultural and Food Chemistry entitled: Liquid Chromatography–Mass Spectrometry-Based Metabolomics for Understanding the Compositional Changes Induced by Oxidative or Anoxic Storage of Red Wines. This work was made in collaboration with the University of Zaragoza. We focused on the metabolomic changes in red wine caused by the redox storage conditions. Is the first paper that analyse the influence of reductive storage in red wine with an untargeted LC-MS protocol. The major metabolomic differences between oxidative and anoxic conditions were linked to reactions of acetaldehyde (favored in oxidative) and SO2 (favored in anoxia). linkSeptember 2020
New publication in Microorganisms entitled: Modulating Wine Aromatic Amino Acid Catabolites by Using Torulaspora delbrueckii in Sequentially Inoculated Fermentations or Saccharomyces cerevisiae Alone. In this work, we focused on the intra- and extracellular metabolomic changes of three aromatic amino acids (tryptophan, tyrosine, and phenylalanine) during alcoholic fermentation. The results indicate that pure S. cerevisiae fermentations produced higher amounts of N-acetyl derivatives of tryptophan and tyrosine and the off-odour molecule 2-aminoacetophenone. The sequentially inoculated fermentations showed a slower evolution and a higher production of metabolites linked to auxin and sulfonated tryptophol.linkJuly 2020
New publication in Scientific Reports entitled: Kinetic investigations of sulfite addition to flavanols. The paper deals with the reactivity of monomeric and dimeric flavanols in the presence of SO2, and the mechanisms of tannins sulfonation. The results proved that: (a) the major sulfonation route that leads quickly and in good yields to monomeric 4β-sulfonated derivatives passes through the acid-catalysed depolymerisation of proanthocyanidins; (b) monomeric flavanols lead to the same 4β-sulfonated products, although in a considerably slower manner, and also to other sulfonated regioisomers; (c) direct sulfonation of epicatechin is slightly faster than that of catechin. linkJune 2020
Free Multilingual Webinar on the impact of short thermical shock and long sub-optimal wine storage on the wine metabolome.linkMay 2020
Released of a public repository data set on MetaboLights (MTBLS784). The data set includes the raw data and meta data of a LC-MS based metabolomics study of the metabolic changes caused by the methyl jasmonate (MeJa) pre-harvest application on two Vitis labrusca L. cultivars grape (Isabel Precoce and Concord), both grown in two Brazilian regions. Grape metabolome was extracted and analyzed with a MS based metabolomics protocol by UPLC-HRMS-QTOF and the unsupervised data analysis reveal clear separation between the two regions and the two cultivars, while supervised data analysis revealed biomarkers between MeJa and control group. Between the biomarkers, stilbenes, hydrocinnamates, flavonols and anthocyanins were identified. These results suggest that MeJa can be used as elicitor to secondary metabolism in grapes grown even under subtropical climate, affecting phenolic biosynthesis.linkApril 2020
New publication on Journal of Agricultural and Food Chemistry. The publication was focused on the use of LC-MS based metabolomics analysis to study the metabolome of Italian monomariatal red wines (Sangiovese from Tuscany, Sangiovese from Romagna, Teroldego from Trentino, Raboso and Corvina from Veneto, Nebbiolo from Piemont, Primitivo from Puglia, Montepulciano from Abruzzo, Sagrantino from Umbria, Aglianico from Campania, Cannonau from Sardegna, and Nerelo Mascalese from Sicily). The study was funded from the MIUR project N. 20157RN44Y.linkApril 2020
Released of a public repository data set on MetaboLights (MTBLS1443). The data set includes the raw data and meta data of a LC-MS based metabolomics study of Italian monomariatal red wines (Sangiovese from Tuscany, Sangiovese from Romagna, Teroldego from Trentino, Raboso and Corvina from Veneto, Nebbiolo from Piemont, Primitivo from Puglia, Montepulciano from Abruzzo, Sagrantino from Umbria, Aglianico from Campania, Cannonau from Sardegna, and Nerelo Mascalese from Sicily). The study was funded from the MIUR project N. 20157RN44Y.linkMarch 2020
Presentation at the Second Annual Meeting of the Cost Action CA17111 Integrape 2020, Ljubljana, Slovenia, entitled: Introduction to FAIR principles about Data, Metadata and Protocols in MetabolomicslinkFebruary 2020
New publication on Food Packaging and Shelf Life. White wines were bottled in green and flint glass bottles and stored under typical supermarket shelf conditions. Light-strike fault, colour changes, light and temperature exposure were monitored up to 50 days. In general, green glass bottles secured wine quality for the tested period. Only a few flint glass bottled wines developed a fault due to light-strike after 1–2 days of supermarket shelf life, but all developed the fault after 20–40 days; so we considered the possibility of two mechanisms causing the problem. Flint-glass bottled wines stored on the bottom shelf developed the defect only slightly later compared with the wines on the top shelf. Moreover, storing the wines in dark and cold after a period of exposure to light did not eliminate the fault, indicating that the defect is probably additive. Monitoring the amount of light to which wines are exposed could prevent the fault.linkJanuary 2020
New publication on Metabolomics journal. The work focused on the effect methyl jasmonate application on Vitis labrusca L. grapes. Methyl jasmonate proved to be a potent elicitor also under tropical and sub-tropical climate conditions, having a great effect on polyphenols profile. If we take in consideration the climate changes in Europe, it could an important tool for the viticulturist in the future. The work was part of Lais Moro PhD project, and made in collaboration between Fondazione Mach (Italy) and University of São Paulo (Brazil). linkJanuary 2020
Article in Revue des Œnologues (issue 174) about the reaction of SO2 in wines. An informative review for the french speaking winemakers of my recent works in wines. linkDecember 2019
Synapt XS arrived at the Metabolomic Platform of FEM and is the first in Europe!linkNovember 2019
New publication on OENO one. The publication was focused on the use of MIR spectroscopy for the discrimination of Italian monomariatal red wines (Sangiovese from Tuscany, Sangiovese from Romagna, Teroldego from Trentino, Raboso and Corvina from Veneto, Nebbiolo from Piemont, Primitivo from Puglia, Montepulciano from Abruzzo, Sagrantino from Umbria, Aglianico from Campania, Cannonau from Sardegna, and Nerelo Mascalese from Sicily). The study was funded from the MIUR project N. 20157RN44Y.Parpinello GP, Ricci A, Arapitsas P, Curioni A, Moio L, Riosegade S, Ugliano M, Versari A. “Multivariate characterisation of Italian monovarietal red wines using MIR spectroscopy“ OENO one 53/4 (2019). linkNovember 2019
New publication. Book Chapter in Italian. Mattivi F, Arapitsas P. “Cambio climatico e profilo polifenolico“ in Il Sangiovese del futuro. Cambiamenti tra clima, vitigno, mercato. Sanguis Jovis, Fondazione Banfi. 2019. ISBN 978-88-94997-01-9October 2019
Part of the PhD defense commission. Universidad de Castilla-La Mancha, PhD student Jose Perez Navarro, Title: En el banco de germoplasma de vid de Castilla-La ManchaSeptember 2019
10th International Workshop on Anthocyanins, 9-11 September 2019 took place at Fondazione Edmund Mach with about 120 participants from over 20 different countries. linkParticipation with two posters and as member of the Organizing and Scientific committee. Extra photos and comments at the official twitter account here> https://twitter.com/IWAnthocyanins1
June 2019
Participation to OENO/IVAS2019 congress at Bordeaux (France), with an oral presentation about the PRIN project (D-Wines: Use of LC-MS metabolomic space to discriminate Italian mono-varietal red wines) and the collaboration in two other presentation (LC-MS based metabolomics and targeted analysis to study the chemical evolution of wines stored under different redox conditions, presented by Ontanon Ignacho; and Multivariate characterization of Italian monovarietal red wines using FTIR spectroscopy presented by prof Versari Andrea).
May 2019
Participation to Enoforum 2019 congress at Vicenza (Italy), with an oral presentation about the PRIN project (D-Wines: Use of LC-MS metabolomic space to discriminate Italian mono-varietal red wines) and an oral presentation about a wine storage project (Metaboliti marcatori del cattivo stato di conservazione del vino).