Research

Our work broadly targets the application of computing to the analysis of biological sequence data. We are primarily focused on data generated by metagenomic experiments - sequencing-based analysis of the microbial communities that inhabit the world.

Our main projects currently are:

• • Metagenomic assembly - computational methods for reconstructing the genomes of organisms from microbial mixtures, with a particular focus on the discovery of genomic variants

  • Diarrheal disease - a key application area in the lab is the study of diarrheal disease in children within the developing world

  • Testing bioinformatics software - we are developing approaches for testing and validating genome assembly algorithms when a known reference sequence is not available.