sample output

If choose long_prt=T in the macro, the following detail will be printed. By default, long_prt=F.

____________________________________________________________________________________________________

Cox propotional hazards for surrogate variables (80) 9

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MAIN80

Dependent Variable eventtime

Censoring Variable bc

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 90710

Number of Observations Used 90710

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

90710 268 90442 99.70

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 6117.909 6079.030

AIC 6117.909 6093.030

SBC 6117.909 6118.167

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 38.8797 7 <.0001

Score 37.4504 7 <.0001

Wald 35.5894 7 <.0001

____________________________________________________________________________________________________

Cox propotional hazards for surrogate variables (80) 10

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

ffqsatf 1 -0.00129 0.01740 0.0055 0.9409 0.999

ffqcalor 1 0.0000774 0.0001232 0.3947 0.5299 1.000

ffqalco 1 0.01127 0.00480 5.5167 0.0188 1.011

agecat1 1 0.43405 0.24410 3.1618 0.0754 1.543

agecat2 1 0.87373 0.22482 15.1033 0.0001 2.396

agecat3 1 0.89731 0.22489 15.9194 <.0001 2.453

agecat4 1 1.03788 0.22808 20.7076 <.0001 2.823

____________________________________________________________________________________________________

cumulative update until time 80 ************ 10:29 Wednesday, February 17, 2010 11

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.00129 0.01740 0.99357 0.83781 1.17829 0.94090

calorie 800.0000 0.00008 0.00012 1.06387 0.87700 1.29056 0.52986

alcohol 25.00000 0.01127 0.00480 1.32544 1.04774 1.67674 0.01884

age 40 - 44 1.00000 0.43405 0.24410 1.54349 0.95658 2.49052 0.07538

age 45 - 49 1.00000 0.87373 0.22482 2.39584 1.54200 3.72248 0.00010

age 50 - 54 1.00000 0.89731 0.22489 2.45299 1.57856 3.81180 0.00007

age 55 + 1.00000 1.03788 0.22808 2.82324 1.80552 4.41461 0.00001

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.00386 0.04843 0.98087 0.61022 1.57666 0.93643

calorie 800.0000 0.00041 0.00052 1.38757 0.61540 3.12859 0.42973

alcohol 25.00000 0.01387 0.00845 1.41450 0.93473 2.14052 0.10087

age 40 - 44 1.00000 0.45811 0.24872 1.58108 0.97104 2.57437 0.06550

age 45 - 49 1.00000 0.91418 0.23796 2.49472 1.56484 3.97717 0.00012

age 50 - 54 1.00000 0.93838 0.23805 2.55583 1.60286 4.07537 0.00008

age 55 + 1.00000 1.03858 0.24495 2.82519 1.74801 4.56617 0.00002

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 82 12

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc2

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 90442

Number of Observations Used 90442

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

90442 337 90105 99.63

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 7690.802 7652.744

AIC 7690.802 7666.744

SBC 7690.802 7693.485

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 38.0574 7 <.0001

Score 38.0719 7 <.0001

Wald 36.9888 7 <.0001

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 82 13

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.00637 0.01553 0.1681 0.6818 0.994

avgalo 1 -0.0001505 0.0001143 1.7332 0.1880 1.000

avgalc 1 0.01264 0.00431 8.6264 0.0033 1.013

agecat1 1 0.23129 0.20537 1.2683 0.2601 1.260

agecat2 1 0.60124 0.18937 10.0808 0.0015 1.824

agecat3 1 0.71643 0.18643 14.7683 0.0001 2.047

agecat4 1 0.76406 0.19265 15.7300 <.0001 2.147

____________________________________________________________________________________________________

cumulative update until time point 82 10:29 Wednesday, February 17, 2010 14

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.00637 0.01553 0.96866 0.83188 1.12792 0.68180

calorie 800.0000 -0.00015 0.00011 0.88657 0.74108 1.06062 0.18800

alcohol 25.00000 0.01264 0.00431 1.37178 1.11089 1.69394 0.00331

age 40 - 44 1.00000 0.23129 0.20537 1.26022 0.84262 1.88477 0.26008

age 45 - 49 1.00000 0.60124 0.18937 1.82438 1.25870 2.64427 0.00150

age 50 - 54 1.00000 0.71643 0.18643 2.04710 1.42053 2.95005 0.00012

age 55 + 1.00000 0.76406 0.19265 2.14698 1.47178 3.13194 0.00007

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.07924 0.08984 0.67286 0.27898 1.62287 0.37774

calorie 800.0000 -0.00068 0.00081 0.58088 0.16386 2.05916 0.40017

alcohol 25.00000 0.02609 0.00995 1.91975 1.17924 3.12528 0.00871

age 40 - 44 1.00000 0.08589 0.24577 1.08969 0.67313 1.76401 0.72673

age 45 - 49 1.00000 0.44145 0.25466 1.55496 0.94394 2.56149 0.08301

age 50 - 54 1.00000 0.56144 0.26222 1.75319 1.04862 2.93116 0.03227

age 55 + 1.00000 0.55484 0.26929 1.74166 1.02740 2.95248 0.03936

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 84 15

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc3

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 90105

Number of Observations Used 90105

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

90105 400 89705 99.56

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 9125.285 9071.135

AIC 9125.285 9085.135

SBC 9125.285 9113.075

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 54.1499 7 <.0001

Score 53.9817 7 <.0001

Wald 51.3652 7 <.0001

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 84 16

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.02221 0.01670 1.7674 0.1837 0.978

avgalo 1 -0.0000466 0.0001110 0.1759 0.6749 1.000

avgalc 1 0.00696 0.00438 2.5250 0.1121 1.007

agecat1 1 0.41458 0.19344 4.5931 0.0321 1.514

agecat2 1 0.64053 0.18423 12.0887 0.0005 1.897

agecat3 1 0.79913 0.18019 19.6688 <.0001 2.224

agecat4 1 1.07702 0.17898 36.2124 <.0001 2.936

____________________________________________________________________________________________________

cumulative update until time point 84 10:29 Wednesday, February 17, 2010 17

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.02221 0.01670 0.89491 0.75977 1.05408 0.18371

calorie 800.0000 -0.00005 0.00011 0.96344 0.80954 1.14660 0.67492

alcohol 25.00000 0.00696 0.00438 1.19002 0.96020 1.47486 0.11205

age 40 - 44 1.00000 0.41458 0.19344 1.51373 1.03607 2.21162 0.03210

age 45 - 49 1.00000 0.64053 0.18423 1.89749 1.32240 2.72267 0.00051

age 50 - 54 1.00000 0.79913 0.18019 2.22361 1.56199 3.16548 0.00001

age 55 + 1.00000 1.07702 0.17898 2.93593 2.06727 4.16960 0.00000

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.08538 0.05302 0.65254 0.38810 1.09716 0.10735

calorie 800.0000 -0.00020 0.00052 0.85465 0.37644 1.94032 0.70731

alcohol 25.00000 0.01546 0.00776 1.47168 1.00621 2.15248 0.04638

age 40 - 44 1.00000 0.32131 0.21012 1.37893 0.91344 2.08163 0.12623

age 45 - 49 1.00000 0.54951 0.21245 1.73240 1.14237 2.62719 0.00970

age 50 - 54 1.00000 0.70130 0.21247 2.01638 1.32958 3.05794 0.00096

age 55 + 1.00000 0.92023 0.21217 2.50988 1.65595 3.80415 0.00001

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 86 18

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc4

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 89705

Number of Observations Used 89705

Summary of the Number of Event and Censored Values

Percent Total Event Censored Censored 89705 498 89207 99.44 Convergence Status Convergence criterion (GCONV=1E-8) satisfied. Model Fit Statistics Without With Criterion Covariates Covariates -2 LOG L 11356.017 11295.058 AIC 11356.017 11309.058 SBC 11356.017 11338.532 Testing Global Null Hypothesis: BETA=0 Test Chi-Square DF Pr > ChiSq Likelihood Ratio 60.9590 7 <.0001 Score 60.2049 7 <.0001 Wald 57.3197 7 <.0001 ____________________________________________________________________________________________________ Cox proporational hazards for main study cumulative until time point 86 19 10:29 Wednesday, February 17, 2010 The PHREG Procedure Analysis of Maximum Likelihood Estimates Parameter Standard Hazard Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio avgsat 1 -0.01572 0.01621 0.9403 0.3322 0.984 avgalo 1 -0.0000511 0.0001024 0.2486 0.6181 1.000 avgalc 1 0.00550 0.00414 1.7663 0.1838 1.006 agecat1 1 0.41048 0.17213 5.6869 0.0171 1.508 agecat2 1 0.63747 0.16394 15.1199 0.0001 1.892 agecat3 1 0.78831 0.16066 24.0742 <.0001 2.200 agecat4 1 1.05129 0.16008 43.1312 <.0001 2.861 ____________________________________________________________________________________________________ cumulative update until time point 86 10:29 Wednesday, February 17, 2010 20 Main study regression coeffiecients: Uncorrected WT B SE HR Low Upp Pvalue satfat 5.00000 -0.01572 0.01621 0.92440 0.78861 1.08359 0.33219 calorie 800.0000 -0.00005 0.00010 0.95996 0.81751 1.12724 0.61808 alcohol 25.00000 0.00550 0.00414 1.14736 0.93682 1.40523 0.18384 age 40 - 44 1.00000 0.41048 0.17213 1.50754 1.07584 2.11247 0.01709 age 45 - 49 1.00000 0.63747 0.16394 1.89169 1.37183 2.60855 0.00010 age 50 - 54 1.00000 0.78831 0.16066 2.19967 1.60545 3.01383 0.00000 age 55 + 1.00000 1.05129 0.16008 2.86133 2.09078 3.91587 0.00000 ________ _______________________________________________________________ Main study regression coefficients: Corrected WT B SE HR Low Upp Pvalue satfat 5.00000 -0.05135 0.03904 0.77355 0.52765 1.13404 0.18832 calorie 800.0000 -0.00022 0.00043 0.83655 0.42607 1.64250 0.60414 alcohol 25.00000 0.01124 0.00665 1.32455 0.95641 1.83440 0.09070 age 40 - 44 1.00000 0.34425 0.18328 1.41093 0.98514 2.02077 0.06034 age 45 - 49 1.00000 0.56941 0.18385 1.76722 1.23252 2.53390 0.00195 age 50 - 54 1.00000 0.71926 0.18290 2.05291 1.43444 2.93803 0.00008 age 55 + 1.00000 0.95043 0.18156 2.58681 1.81223 3.69246 0.00000 ________ _______________________________________________________________ ____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 88 21

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc5

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 89207

Number of Observations Used 89207

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

89207 515 88692 99.42

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 11737.827 11687.398

AIC 11737.827 11701.398

SBC 11737.827 11731.107

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 50.4285 7 <.0001

Score 50.7517 7 <.0001

Wald 48.9445 7 <.0001

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 88 22

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 0.01570 0.01601 0.9619 0.3267 1.016

avgalo 1 0.0001170 0.0000978 1.4306 0.2317 1.000

avgalc 1 0.00514 0.00412 1.5556 0.2123 1.005

agecat1 1 0.33323 0.16294 4.1823 0.0408 1.395

agecat2 1 0.55411 0.15515 12.7560 0.0004 1.740

agecat3 1 0.64717 0.15369 17.7323 <.0001 1.910

agecat4 1 0.95252 0.15220 39.1662 <.0001 2.592

____________________________________________________________________________________________________

cumulative update until time point 88 10:29 Wednesday, February 17, 2010 23

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 0.01570 0.01601 1.08168 0.92460 1.26546 0.32671

calorie 800.0000 0.00012 0.00010 1.09811 0.94198 1.28011 0.23166

alcohol 25.00000 0.00514 0.00412 1.13726 0.92913 1.39200 0.21231

age 40 - 44 1.00000 0.33323 0.16294 1.39547 1.01396 1.92051 0.04085

age 45 - 49 1.00000 0.55411 0.15515 1.74040 1.28406 2.35891 0.00035

age 50 - 54 1.00000 0.64717 0.15369 1.91013 1.41333 2.58157 0.00003

age 55 + 1.00000 0.95252 0.15220 2.59223 1.92361 3.49325 0.00000

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 0.02556 0.03658 1.13634 0.79402 1.62624 0.48465

calorie 800.0000 0.00051 0.00043 1.50936 0.76866 2.96382 0.23179

alcohol 25.00000 0.00234 0.00672 1.06022 0.76273 1.47375 0.72781

age 40 - 44 1.00000 0.38743 0.17689 1.47318 1.04156 2.08368 0.02851

age 45 - 49 1.00000 0.65157 0.17788 1.91855 1.35382 2.71886 0.00025

age 50 - 54 1.00000 0.75328 0.17834 2.12394 1.49739 3.01267 0.00002

age 55 + 1.00000 1.01235 0.17537 2.75206 1.95154 3.88094 0.00000

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 90 24

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc6

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 88692

Number of Observations Used 88692

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

88692 551 88141 99.38

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 12551.723 12489.097

AIC 12551.723 12503.097

SBC 12551.723 12533.280

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 62.6252 7 <.0001

Score 62.9580 7 <.0001

Wald 61.5712 7 <.0001

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 90 25

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.03140 0.01670 3.5367 0.0600 0.969

avgalo 1 -0.0002961 0.0001017 8.4721 0.0036 1.000

avgalc 1 0.00802 0.00400 4.0197 0.0450 1.008

agecat1 1 0.13273 0.15605 0.7234 0.3950 1.142

agecat2 1 0.34548 0.14777 5.4659 0.0194 1.413

agecat3 1 0.68449 0.13947 24.0862 <.0001 1.983

agecat4 1 0.65389 0.14664 19.8845 <.0001 1.923

____________________________________________________________________________________________________

cumulative update until time point 90 10:29 Wednesday, February 17, 2010 26

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.03140 0.01670 0.85469 0.72568 1.00665 0.06002

calorie 800.0000 -0.00030 0.00010 0.78909 0.67276 0.92555 0.00361

alcohol 25.00000 0.00802 0.00400 1.22202 1.00450 1.48663 0.04497

age 40 - 44 1.00000 0.13273 0.15605 1.14194 0.84103 1.55053 0.39502

age 45 - 49 1.00000 0.34548 0.14777 1.41267 1.05744 1.88724 0.01939

age 50 - 54 1.00000 0.68449 0.13947 1.98276 1.50852 2.60610 0.00000

age 55 + 1.00000 0.65389 0.14664 1.92301 1.44265 2.56332 0.00001

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.08253 0.04433 0.66191 0.42867 1.02206 0.06266

calorie 800.0000 -0.00127 0.00053 0.36064 0.15647 0.83124 0.01667

alcohol 25.00000 0.02059 0.00781 1.67326 1.14093 2.45396 0.00842

age 40 - 44 1.00000 -0.04900 0.20107 0.95218 0.64204 1.41213 0.80746

age 45 - 49 1.00000 0.10189 0.20418 1.10726 0.74207 1.65217 0.61776

age 50 - 54 1.00000 0.44406 0.20189 1.55902 1.04955 2.31580 0.02784

age 55 + 1.00000 0.43576 0.20320 1.54613 1.03819 2.30258 0.03200

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 92 27

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc7

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 88141

Number of Observations Used 88141

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

88141 540 87601 99.39

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 12294.457 12281.857

AIC 12294.457 12295.857

SBC 12294.457 12325.898

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 12.5993 7 0.0825

Score 12.9850 7 0.0725

Wald 12.9023 7 0.0745

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 92 28

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.00880 0.01693 0.2702 0.6032 0.991

avgalo 1 -0.0000311 0.0000998 0.0969 0.7555 1.000

avgalc 1 0.00550 0.00425 1.6736 0.1958 1.006

agecat1 1 0.11881 0.14167 0.7033 0.4017 1.126

agecat2 1 0.23020 0.13725 2.8132 0.0935 1.259

agecat3 1 0.16060 0.14061 1.3045 0.2534 1.174

agecat4 1 0.41667 0.14036 8.8127 0.0030 1.517

____________________________________________________________________________________________________

cumulative update until time point 92 10:29 Wednesday, February 17, 2010 29

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.00880 0.01693 0.95696 0.81068 1.12964 0.60322

calorie 800.0000 -0.00003 0.00010 0.97544 0.83409 1.14074 0.75553

alcohol 25.00000 0.00550 0.00425 1.14737 0.93164 1.41306 0.19577

age 40 - 44 1.00000 0.11881 0.14167 1.12616 0.85311 1.48660 0.40167

age 45 - 49 1.00000 0.23020 0.13725 1.25886 0.96194 1.64743 0.09349

age 50 - 54 1.00000 0.16060 0.14061 1.17421 0.89137 1.54681 0.25340

age 55 + 1.00000 0.41667 0.14036 1.51691 1.15208 1.99726 0.00299

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.02710 0.03023 0.87326 0.64936 1.17435 0.36990

calorie 800.0000 -0.00017 0.00042 0.87559 0.45224 1.69524 0.69348

alcohol 25.00000 0.00877 0.00612 1.24500 0.92247 1.68030 0.15201

age 40 - 44 1.00000 0.07654 0.15151 1.07955 0.80219 1.45281 0.61341

age 45 - 49 1.00000 0.18964 0.15651 1.20882 0.88948 1.64280 0.22563

age 50 - 54 1.00000 0.12251 0.16029 1.13033 0.82558 1.54757 0.44471

age 55 + 1.00000 0.35670 0.15607 1.42861 1.05212 1.93982 0.02228

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 94 30

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc8

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 87601

Number of Observations Used 87601

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

87601 566 87035 99.35

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 12879.281 12854.314

AIC 12879.281 12868.314

SBC 12879.281 12898.684

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 24.9671 7 0.0008

Score 25.0717 7 0.0007

Wald 24.8217 7 0.0008

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 94 31

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.03820 0.01744 4.7951 0.0285 0.963

avgalo 1 0.0000712 0.0000990 0.5181 0.4716 1.000

avgalc 1 0.00468 0.00424 1.2195 0.2695 1.005

agecat1 1 0.26165 0.14070 3.4581 0.0629 1.299

agecat2 1 0.27766 0.13932 3.9717 0.0463 1.320

agecat3 1 0.52368 0.13354 15.3791 <.0001 1.688

agecat4 1 0.25355 0.14913 2.8907 0.0891 1.289

____________________________________________________________________________________________________

cumulative update until time point 94 10:29 Wednesday, February 17, 2010 32

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.03820 0.01744 0.82614 0.69632 0.98016 0.02854

calorie 800.0000 0.00007 0.00010 1.05864 0.90648 1.23636 0.47164

alcohol 25.00000 0.00468 0.00424 1.12413 0.91332 1.38360 0.26946

age 40 - 44 1.00000 0.26165 0.14070 1.29907 0.98597 1.71159 0.06294

age 45 - 49 1.00000 0.27766 0.13932 1.32003 1.00460 1.73451 0.04627

age 50 - 54 1.00000 0.52368 0.13354 1.68823 1.29946 2.19331 0.00009

age 55 + 1.00000 0.25355 0.14913 1.28859 0.96200 1.72607 0.08909

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.07170 0.02978 0.69872 0.52188 0.93549 0.01605

calorie 800.0000 0.00018 0.00042 1.15761 0.59901 2.23716 0.66326

alcohol 25.00000 0.00875 0.00592 1.24447 0.93116 1.66318 0.13941

age 40 - 44 1.00000 0.22285 0.15175 1.24963 0.92813 1.68249 0.14196

age 45 - 49 1.00000 0.26353 0.15933 1.30152 0.95241 1.77859 0.09814

age 50 - 54 1.00000 0.50008 0.15514 1.64885 1.21652 2.23481 0.00127

age 55 + 1.00000 0.16616 0.16452 1.18076 0.85530 1.63005 0.31252

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 96 33

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc9

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 87035

Number of Observations Used 87035

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

87035 642 86393 99.26

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 14599.761 14576.995

AIC 14599.761 14590.995

SBC 14599.761 14622.248

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 22.7655 7 0.0019

Score 22.0933 7 0.0024

Wald 21.8838 7 0.0027

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 96 34

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.02702 0.01619 2.7851 0.0951 0.973

avgalo 1 0.0001719 0.0000921 3.4832 0.0620 1.000

avgalc 1 0.00101 0.00422 0.0567 0.8118 1.001

agecat1 1 0.23255 0.13342 3.0382 0.0813 1.262

agecat2 1 0.34481 0.12950 7.0896 0.0078 1.412

agecat3 1 0.41496 0.12868 10.3991 0.0013 1.514

agecat4 1 0.45378 0.13428 11.4200 0.0007 1.574

____________________________________________________________________________________________________

cumulative update until time point 96 10:29 Wednesday, February 17, 2010 35

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.02702 0.01619 0.87365 0.74548 1.02385 0.09515

calorie 800.0000 0.00017 0.00009 1.14740 0.99312 1.32564 0.06200

alcohol 25.00000 0.00101 0.00422 1.02545 0.83378 1.26118 0.81183

age 40 - 44 1.00000 0.23255 0.13342 1.26182 0.97147 1.63894 0.08133

age 45 - 49 1.00000 0.34481 0.12950 1.41172 1.09526 1.81961 0.00775

age 50 - 54 1.00000 0.41496 0.12868 1.51431 1.17674 1.94872 0.00126

age 55 + 1.00000 0.45378 0.13428 1.57426 1.20997 2.04823 0.00073

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.04694 0.02967 0.79082 0.59129 1.05768 0.11365

calorie 800.0000 0.00064 0.00043 1.67316 0.85863 3.26038 0.13048

alcohol 25.00000 0.00085 0.00603 1.02155 0.76010 1.37293 0.88759

age 40 - 44 1.00000 0.25726 0.15211 1.29338 0.95994 1.74264 0.09080

age 45 - 49 1.00000 0.41457 0.15737 1.51372 1.11196 2.06064 0.00843

age 50 - 54 1.00000 0.47205 0.15785 1.60328 1.17665 2.18459 0.00278

age 55 + 1.00000 0.43639 0.15751 1.54711 1.13617 2.10667 0.00560

________ _______________________________________________________________

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 98 36

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Model Information

Data Set WORK.MALL

Dependent Variable eventtime

Censoring Variable bc10

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 86393

Number of Observations Used 86393

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

86393 1350 85043 98.44

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 30669.242 30621.725

AIC 30669.242 30635.725

SBC 30669.242 30672.180

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 47.5170 7 <.0001

Score 50.2430 7 <.0001

Wald 50.1925 7 <.0001

____________________________________________________________________________________________________

Cox proporational hazards for main study cumulative until time point 98 37

10:29 Wednesday, February 17, 2010

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio

avgsat 1 -0.04696 0.01155 16.5401 <.0001 0.954

avgalo 1 0.0000795 0.0000649 1.4991 0.2208 1.000

avgalc 1 0.01226 0.00259 22.3477 <.0001 1.012

agecat1 1 0.04689 0.08648 0.2940 0.5877 1.048

agecat2 1 0.10842 0.08457 1.6435 0.1998 1.115

agecat3 1 0.11907 0.08508 1.9588 0.1616 1.126

agecat4 1 0.07230 0.09144 0.6251 0.4291 1.075

____________________________________________________________________________________________________

cumulative update until time point 98 10:29 Wednesday, February 17, 2010 38

Main study regression coeffiecients: Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.04696 0.01155 0.79071 0.70611 0.88546 0.00005

calorie 800.0000 0.00008 0.00006 1.06564 0.96252 1.17981 0.22080

alcohol 25.00000 0.01226 0.00259 1.35853 1.19646 1.54255 0.00000

age 40 - 44 1.00000 0.04689 0.08648 1.04801 0.88461 1.24159 0.58766

age 45 - 49 1.00000 0.10842 0.08457 1.11451 0.94428 1.31544 0.19984

age 50 - 54 1.00000 0.11907 0.08508 1.12645 0.95344 1.33085 0.16164

age 55 + 1.00000 0.07230 0.09144 1.07497 0.89859 1.28597 0.42915

________ _______________________________________________________________

Main study regression coefficients: Corrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.09362 0.01996 0.62620 0.51497 0.76147 0.00000

calorie 800.0000 0.00011 0.00030 1.08830 0.68449 1.73034 0.72060

alcohol 25.00000 0.01768 0.00372 1.55589 1.29653 1.86714 0.00000

age 40 - 44 1.00000 -0.02480 0.09923 0.97550 0.80308 1.18494 0.80263

age 45 - 49 1.00000 0.07186 0.10418 1.07451 0.87605 1.31792 0.49031

age 50 - 54 1.00000 0.07449 0.10510 1.07734 0.87677 1.32378 0.47848

age 55 + 1.00000 -0.06910 0.10633 0.93324 0.75767 1.14949 0.51581

________ _______________________________________________________________

If short_prt=T and long_prt=F, the following summary will be printed. By default, short_prt=T.

___________________________________________________________________________________________________

10:29 Wednesday, February 17, 2010 40

The PHREG Procedure

Model Information

Data Set WORK.NEW

Dependent Variable eventtime

Censoring Variable bc

Censoring Value(s) 0

Ties Handling BRESLOW

Number of Observations Read 90710

Number of Observations Used 90710

Summary of the Number of Event and Censored Values

Percent

Total Event Censored Censored

90710 5667 85043 93.75

Convergence Status

Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics

Without With

Criterion Covariates Covariates

-2 LOG L 129022.30 128744.12

AIC 129022.30 128758.12

SBC 129022.30 128804.62

Testing Global Null Hypothesis: BETA=0

Test Chi-Square DF Pr > ChiSq

Likelihood Ratio 278.1811 7 <.0001

Score 277.7296 7 <.0001

Wald 274.1862 7 <.0001

____________________________________________________________________________________________________

10:29 Wednesday, February 17, 2010 41

The PHREG Procedure

Analysis of Maximum Likelihood Estimates

Parameter Standard Hazard 95% Hazard Ratio

Variable DF Estimate Error Chi-Square Pr > ChiSq Ratio Confidence Limits

ffqsatf 1 -0.02110 0.00495 18.1394 <.0001 0.979 0.970 0.989

ffqcalor 1 0.0000127 0.0000304 0.1753 0.6755 1.000 1.000 1.000

ffqalco 1 0.00772 0.00124 38.5278 <.0001 1.008 1.005 1.010

agecat1 1 0.20208 0.04602 19.2795 <.0001 1.224 1.118 1.339

agecat2 1 0.35800 0.04419 65.6189 <.0001 1.430 1.312 1.560

agecat3 1 0.46370 0.04355 113.3711 <.0001 1.590 1.460 1.732

agecat4 1 0.54168 0.04501 144.8246 <.0001 1.719 1.574 1.877

____________________________________________________________________________________________________

10:29 Wednesday, February 17, 2010 42

Combined cumulative updated Uncorrected

WT B SE HR Low Upp Pvalue

satfat 5.00000 -0.02110 0.00495 0.89989 0.85725 0.94465 0.00002

calorie 800.0000 0.00001 0.00003 1.01023 0.96322 1.05954 0.67547

alcohol 25.00000 0.00772 0.00124 1.21284 1.14114 1.28904 0.00000

age 40 - 44 1.00000 0.20208 0.04602 1.22395 1.11837 1.33949 0.00001

age 45 - 49 1.00000 0.35800 0.04419 1.43046 1.31177 1.55989 0.00000

age 50 - 54 1.00000 0.46370 0.04355 1.58995 1.45987 1.73162 0.00000

age 55 + 1.00000 0.54168 0.04501 1.71890 1.57375 1.87744 0.00000

________ _______________________________________________________________

____________________________________________________________________________________________________

10:29 Wednesday, February 17, 2010 43

Combined cumulative corrected

beta se HR low upp pval

satfat -0.05509 0.01134 0.75923 0.67940 0.84845 0.00000

calorie 0.00006 0.00015 1.04556 0.83157 1.31463 0.70294

alcohol 0.01178 0.00208 1.34241 1.21208 1.48676 0.00000

age 40 - 44 0.16090 0.05404 1.17457 1.05653 1.30580 0.00291

age 45 - 49 0.33202 0.05564 1.39378 1.24978 1.55437 0.00000

age 50 - 54 0.42032 0.05594 1.52245 1.36435 1.69887 0.00000

age 55 + 0.43443 0.05619 1.54408 1.38307 1.72384 0.00000