Juan de los Santos was a sculptor specializing in religious imagery. His ivory sculptures, such as The Crucifixion, showcase intricate craftsmanship and were often used in Catholic liturgical practices. These sculptures were highly valued during the Spanish colonial period and symbolized the integration of Christian iconography into Filipino art.

The Santo Niño de Cebu sculpture is a significant artwork from the Spanish colonial regime. While it was brought to the Philippines by Ferdinand Magellan and originates from Europe, it became an essential symbol in the Spanish efforts to Christianize the Filipino people. The image of the Santo Niño played a central role in the missionary activities of the Spanish colonizers, helping spread Catholicism across the islands. Its continued reverence today highlights the lasting influence of Spanish colonization on Filipino religious practices and culture.