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Page 2 of 4 • J Angiol Vasc Surg ISSN: 2572-7397, Open Access Journal DOI: 10.24966/AVS-7397/100075 Volume 6 • Issue 2 • 100075 The restoration of the varicose veins initially leads to a significant reduction in venous pressure in the entire venous tract up to the capillaries. The accompanying oxygen therapy generates a significant increase in the oxygen partial pressure with improved oxygen saturation the cells and thus also leads to a swelling of the microcirculatory vessels. Two different therapy concepts with a clear effect synergy - improvement of the microcirculation in the legs (Figure 2). We have decided to offer this accompanying therapy to our patients with immediate effect. We carry out this therapy parallel to the postoperative compression massage therapy. This massage therapy is carried out post op after every catheter intervention like VenaSeal®, radio frequency or micro-foam. The compression therapy lasts 25-30 minutes, the oxygen therapy is used over the entire course of the compression massage [5,6]. Saphenion®: Oxygen multistep therapy for varicose veins - study design We have been conducting a prospective randomized study over 10 months now to clarify the therapeutic effects of post-operative massage therapy and oxygen multi-step therapy. In the course of the last 10 months, 127 patients were initially treated with 30 minutes of massage and 30 minutes of SMT after the VenaSeal® - and every micro-foam intervention. Of these patients, 118 operated on continued the follow-up treatment for a further 4-6 weeks. Of 127 patients, 9 patients (7.1%) refrained from further treatments after the first SMT and continued to receive compression therapy. They were excluded from the study. The remaining 118 patients received additional SMT in conjunction with compression therapy (3-7 sessions) after the vein glue and each micro-foam session. In addition, 23 patients (18.1%) wanted to continue the combination compression therapy / SMT after varicose vein therapy. The clinical and sonographic examinations we have done at the first day, 14 days, 4 weeks and 3 months after therapy with the vein glue and micro-foam (Figure 3). Saphenion®: Oxygen multistep-therapy for varicose veins -Results of our study We have been conducting this prospective study on the results of postoperative oxygen Multistep Therapy (SMT) for 6 months. After the therapy with the vein glue „VenaSeal®“, as well as after all micro-foam sessions, all participating patients are treated for 30 minutes using multi-chamber compression therapy and SMT. In addition to the changes in measurement technology, our main aim is to determine any clinical improvements immediately after the treatment of varicose veins with the various catheter systems. Basically, we place 2 oxygen sensors before and after the massage and oxygen therapy- one on the toe and one on the finger. The 118 patients included in the test so far (average age: 56 years, 28-85 years) showed a pre therapeutic difference in the oxygen content on the finger compared to the measurement on the forefoot of 3-25% (96-74%). These sometime differences in the resting phase before the start of therapy alone suggest that an existing varicose vein on the legs can lead to a reduced oxygen content of the blood in the lower extremity. None of these patients had any signs of leg artery disease either. After the 30-minute oxygen multi-step therapy, we were able to determine an increase in the oxygen content in the blood of up to 18% (82%-99%) when taking measurements on the fingers. But the effect was much clearer on the feet. There, almost complete compensation for the difference between the hand and foot that existed before the oxygen therapy was achieved. At the foot, increases in the oxygen content of up to 28% (72% to 99% oxygen) were measured. The analysis of the total group of 118 patients showed an improvement in the oxygen content of 2-11% (up to 10% increase) in the younger patients (28-55 years of age). In the group of 55 - 85 years old patients, we saw an improvement in the bloodoxygen content of 5-35% (up to 27% increase) [7,8] (Figure 4). Figure 1: Oxygen therapy for varicose veins: swelling of the capillary walls and
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