Dr. Takeshi Izawa Publications

Original papers published in major journals

Cell　1 paper

Nature　1 paper

Science　1 paper

Nature Plants 1 paper

Nature Genetics　2 papers

Genes&Development　2 papers

PNAS　2 papers

The Plant Cell　6 papers

The Plant Journal　7 papers

Plant Physiolosy　4 papers

Plant Cell Physiolosy　7 papers

2025年

Sun R, Ding Y, Mimura M, Nishide N, Izawa T. (2025). Temporal transcriptome analysis reveals the two-phase action of florigens in rice flowering. Theore Appl Genet, 138(5), 100.

Toda E, Koshimizu S, Kinoshita A, Higashiyama T, Izawa T, Yano K, Okamoto T. (2025). Transcriptional dynamics during karyogamy in rice zygotes. Development, 152(2), DEV204497.

2023年

Nishiyama N, Shinozawa A, Matsumoto T, Izawa T. (2023). High genome heterozygosity revealed vegetative propagation over the sea in Moso bamboo. BMC genomics, 24(1), 348.

Cui J, Nishide N, Mashiguchi K, Kuroha K, Miya M, Sugimoto K, Itoh J. I., Yamaguchi S, Izawa T. (2023). Fertilization controls tiller numbers via transcriptional regulation of a MAX1-like gene in rice cultivation. Nature communications, 14(1), 3191. 

2022年

Izawa T. (2022). Reloading DNA History in Rice Domestication. Plant & cell physiology, 63(11), 1529–1539. 

2021年

Nagalla AD, Nishide N, Hibara KI, Izawa T. (2021) High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice. Plant Cell Physiol. pcab129. Epub ahead of print. LINK

2020年

Izawa T. (2020) What is going on with the hormonal control of flowering in plants? Plant J. 105(2):431-445. LINK

2018年

Itoh H, Tanaka Y, Izawa T. (2018) Genetic Relationship Between Phytochromes and OsELF3-1 Reveals the Mode of Regulation for the Suppression of Phytochrome Signaling in Rice. Plant Cell Physiol. 60(3):549-561. LINK

Itoh H, Wada KC, Sakai H, Shibasaki K, Fukuoka S, Wu J, Yonemaru JI, Yano M, Izawa T. (2018) Genomic adaptation of flowering-time genes during the expansion of rice cultivation area. Plant J. 94(5):895-909. LINK

2017年

Nemoto Y, Hori K, Izawa T (2017) Fine-tuning of the setting of critical day length by two casein kinases in rice photoperiodic flowering. Journal of Experimental Botany LINK

Okada R, Nemoto Y, Endo-Higashi N, Izawa T (2017) Synthetic control of flowering in rice independent of the cultivation environment. Nature Plants 3, Article number: 17039. LINK

2016年

Nemoto Y, Nonoue Y, Yano M, Izawa T. (2016) Hd1, a CONSTANS Orthlog in Rice, Function as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7. ThePlant J. doi: 10.1111/tpj.13168. [Epub ahead of print] LINK

2015年

Oikawa T, Maeda H, Oguchi T, Yamaguchi T, Tanabe N, Ebana K, Yano M, Ebitani T, Izawa T (2015) The birth of a black rice gene and its local spread by introgression. The Plant Cell 27:2401-2414. LINK

Matsuzaki J, Kawahara Y, Izawa T. (2015) Punctual transcriptional regulation by the rice circadian clock under fluctuating field conditions. The Plant Cell. 27:633-648. LINK

井澤 毅 （2015） 短日植物イネが夏至の頃に花芽形成を起こす!?－光周性花芽形成能の生物学的意義について－. 生物時計の生態学 リズムを刻む生物の世界．種生物学会（編）．文一総合出版．LINK

Izawa T (2015) Deciphering and Prediction of plant dynamics under field conditions Curr Opin Plant Biol. 24:87-92. LINK

2014年

Osugi A, Izawa T (2014) Critical gates in day-length recognition to control the photoperiodic flowering Advances in Bot. Res. 72:103-130. LINK

井澤 毅 (2014) 絶対的光周性花成と条件的光周性花成－短日植物イネを例に－. 植物の生長調節49: 41-48. LINK

2013年

Itoh H, Izawa T. (2013) The coincidence of critical day length recognition for florigen gene expression and floral transition under long-day conditions in rice. Mol Plant. 6:635-649. LINK

2012年

Nagano AJ, Sato Y, Mihara M, Antonio BA, Motoyama R, Itoh H, Nagamura Y, Izawa T. (2012) Deciphering and prediction of transcriptome dynamics under fluctuating field conditions. Cell 151:1358-1369. LINK

Ikeda-Kawakatsu K, Maekawa M, Izawa T, Itoh J, Nagato Y. (2012) ABERRANT PANICLE ORGANIZATION 2/RFL, the rice ortholog of Arabidopsis LEAFY, suppresses the transition from inflorescence meristem to floral meristem through interaction with APO1. Plant J. 69:168-180. LINK

Izawa T (2012) Physiological significance of the plant circadian clock in natural field conditions. Plant, Cell and Environ.35: 1729-1741. LINK

2011年

Tanaka N, Itoh H, Sentoku N, Kojima M, Sakakibara H, Izawa T, Itoh J, Nagato Y. (2011) The COP1 ortholog PPS regulates the juvenile-adult and vegetative-reproductive phase changes in rice. The Plant Cell 23:2143-2154. LINK

Itoh H and Izawa T. (2011) A study of phytohormone biosynthetic gene expression using a circadian clock-related mutant in rice. Plant Signaling & Behavior 6: 1932-1936. LINK

Osugi A, Itoh H, Ikeda-Kawakatsu K, Takano M, Izawa T. (2011) Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice. Plant Physiol. 157:1128-1137. LINK

Izawa T, Mihara M, Suzuki Y, Gupta M, Itoh H, Nagano AJ, Motoyama R, Sawada Y, Yano M, Hirai MY, Makino A, Nagamura Y. (2011) Os-GIGANTEA confers robust diurnal rhythms on the global transcriptome of rice in the field. The Plant Cell 23:1741-1755. LINK

Endo-Higashi N, Izawa T. (2011) Flowering-time genes Heading date 1 and Early heading date 1 together control panicle development in rice. Plant Cell Physiol. 52:1083-1094. LINK

Akasaka M, Konishi S, Izawa T, Ushiki J (2011) Histological and genetic characteristics associated with the seed-shattering habit of weedy rice (Oryza sativa L.) from Okayama, Japan Breeding Science 61:168-173. LINK

井澤 毅 （2011） 農業生産と体内時計の切っても切れない深い関係．体内時計の科学と産業応用．柴田重信（監）シーエムシー出版．pp125-133．LINK

伊藤博紀, 井澤 毅 (2011) 光応答と開花制御：日の長さの変化を認識して花を咲かせるメカニズム. 細胞工学 30:161-166.LINK

2010年

Fujino K, Wu J, Sekiguchi H, Ito T, Izawa T, Matsumoto T. (2010) Multiple introgression events surrounding the Hd1 flowering-time gene in cultivated rice, Oryza sativa L. Mol Genet Genomics. 284:137-146. LINK

Itoh H, Nonoue Y, Yano M, Izawa T. (2010) A pair of floral regulators sets critical day length for Hd3a florigen expression in rice. Nat Genet. 42:635-638. LINK

Ogiso E, Takahashi Y, Sasaki T, Yano M, Izawa T. (2010) The role of casein kinase II in flowering time regulation has diversified during evolution. Plant Physiol. 152:808-820. LINK

Mihara M, Itoh T, Izawa T. (2010) SALAD database: a motif-based database of protein annotations for plant comparative genomics. Nucleic Acids Res. 38 (Database issue) :D835-842. LINK

Izawa T. (2010) Photoperiodic control of flowering in the short day plant Oryza sativa Photoperiodism : The Biological Calendar. Nelson,Denlinger, and Somers (Eds) Oxford. pp38-58.LINK

2009年

海老原史樹文 井澤 毅（編集）（2009）光周性の分子生物学. シュプリンガージャパン.LINK

井澤 毅 (2009) イネにとっての短日光周性花芽形成. 光周性の分子生物学. 海老原・井澤（編）. シュプリンガージャパン. pp77-87.LINK

井澤 毅（2009）ゲノムで植物の進化を探る．－イネの栽培化を例に－. 研究をささえるモデル生物．吉川・堀（編）. 化学同人．pp153-155．LINK

井澤 毅 (2009) シロイヌナズナには存在しないイネに独特な光周性花芽誘導分子機構 植物の生長調節 44:118-127. LINK

Izawa T, Konishi S, Shomura A, Yano M. (2009) DNA changes tell us about rice domestication. Curr Opin Plant Biol. 12:185-192. LINK

2008年

Matsubara K, Yamanouchi U, Wang Z-X, Minobe Y, Izawa T, Yano M (2008) Ehd2, a rice ortholog of the maize INDETERMINATE1 gene, promotes flowering by up-regulating Ehd1. Plant Physiol. 148:1425-1435. LINK

Mihara M, Itoh T, Izawa T. (2008) In silico identification of short nucleotide sequences associated with gene expression of pollen development in rice. Plant Cell Physiol. 49:1451-1464. LINK

Konishi S, Ebana K, Izawa T. (2008) Inference of the japonica rice domestication process from the distribution of six functional nucleotide polymorphisms of domestication-related genes in various landraces and modern cultivars. Plant Cell Physiol. 49:1283-1293. LINK

Shomura A, Izawa T(co-first), Ebana K, Ebitani T, Kanegae H, Konishi S, Yano M. (2008) Deletion in a gene associated with grain size increased yields during rice domestication. Nat Genet. 40:1023-1028.LINK

Izawa T (2008) Photoperiodic flowering in rice. Rice Biology in the Genomics Era. Hirano, Hrai, Sano, and Sasaki (Eds). Springer. pp163-176. LINK

Izawa T (2008) The Process of Rice Domestication: A new model based on recent data Rice 1: 127-134. LINK

井澤 毅 (2008) イネはいかに雑草から作物になったのか？ －温故知新の分子生物学－ 科学 78:1055-1057.

2007年

Izawa T. (2007) Adaptation of flowering-time by natural and artificial selection in Arabidopsis and rice. J Exp Bot. 58:3091-3097. LINK

Izawa T. (2007) Daylength measurements by rice plants in photoperiodic short-day flowering. Int Rev Cytol. 256:191-222. LINK

井澤 毅, 小西左江子, 江花薫子, 矢野昌裕 (2007) 夏至に花芽をつける短日植物のイネ－イネの栽培化でなにが起こったのか？－ 蛋白質・核酸・酵素 52:1925-1930. LINK

井澤 毅 (2007) 特集にあたって－なぜ、いま、栽培化研究なのか？－ 蛋白質・核酸・酵素 52:1919-1924. LINK

小西 左江子, 矢野 昌裕, 井澤 毅 (2007) イネはどのように栽培化されたのか？－イネ脱粒性遺伝子の単離から見えてきたこと－ 農業および園芸 82:445-456. LINK

井澤 毅, 小西左江子, 矢野昌裕 (2007) イネ栽培化の鍵となった脱粒性遺伝子のDNA変異の同定と利用 農林水産技術研究ジャーナル 30(3):34-37. LINK

2006年

Konishi S, Izawa T (co-first), Lin SY, Ebana K, Fukuta Y, Sasaki T, Yano M. (2006) An SNP caused loss of seed shattering during rice domestication. Science 312:1392-1396. LINK

小西 左江子, 井澤 毅, 矢野 昌裕 (2006) イネ脱粒性遺伝子の単離と栽培化における役割 ブレインテクノニュース (117):14-18. LINK

2005年

Moritoh S, Miki D, Akiyama M, Kawahara M, Izawa T, Maki H, Shimamoto K. (2005) RNAi-mediated silencing of OsGEN-L (OsGEN-like), a new member of the RAD2/XPG nuclease family, causes male sterility by defect of microspore development in rice. Plant Cell Physiol. 46:699-715. LINK

Izawa T (2005). Comparative Molecular biology in photoperiodic flowering between the short-day plant rice and the long-day plant Arabidopsis. Light Sensing in Plants. Springer. pp333-337. LINK

2004年

Doi K, Izawa T (co-first), Fuse T, Yamanouchi U, Kubo T, Shimatani Z, Yano M, Yoshimura A. (2004) Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1. Genes Dev. 18:926-936. LINK

Kaneko M, Inukai Y, Ueguchi-Tanaka M, Itoh H, Izawa T, Kobayashi Y, Hattori T, Miyao A, Hirochika H, Ashikari M, Matsuoka M. (2004) Loss-of-function mutations of the rice GAMYB gene impair alpha-amylase expression in aleurone and flower development. The Plant Cell 16:33-44. LINK

井澤 毅 (2004) 植物の光周性花芽誘導．時計遺伝子の分子生物学．岡村・深田 (編). シュプリンガーフェアラーク東京．pp125-130．LINK

井澤 毅 (2004) 序 「理想のイネ」をもとめて, 1章 イネ研究の流れと分子遺伝学 (分担執筆）, 6章 信号伝達研究 (分担執筆). イネゲノム配列解読で何ができるのか 研究目標と戦略策定のために. 矢野・松岡 (編). 農文協. pp13-18, 19-29,103-114,120-122. LINK

井澤 毅/矢野 昌裕 (2004) 理想のイネを目指して！－これからのイネ研究戦略―. 食品工業 2004年12月15日号: 1-10.

2003年

Izawa T, Takahashi Y, Yano M. (2003) Comparative biology comes into bloom: genomic and genetic comparison of flowering pathways in rice and Arabidopsis. Curr Opin Plant Biol. 6:113-120. LINK

井澤 毅 (2003) 花芽誘導の分子機構－「花咲じいさん」を探して―. バイオサイエンスとインダストリー61: 17-22. LINK

2002年

Izawa T, Oikawa T, Sugiyama N, Tanisaka T, Yano M, Shimamoto K. (2002) Phytochrome mediates the external light signal to repress FT orthologs in photoperiodic flowering of rice. Genes Dev.16:2006-2020. LINK

Hayama R, Izawa T, Shimamoto K. (2002) Isolation of rice genes possibly involved in the photoperiodic control of flowering by a fluorescent differential display method. Plant Cell Physiol. 43:494-504. LINK

井澤 毅 (2002) 季節を予期する植物たち－遺伝子から見た短日植物と長日植物の日長認識機構―. 化学と生物40: 719-724. LINK

2001年

Sugiyama N, Izawa T (co-first), Oikawa T, Shimamoto K. (2001) Light regulation of circadian clock-controlled gene expression in rice. Plant J. 26:607-615. LINK

井澤 毅 (2001）光シグナルによる花成誘導 －植物はいかに日の長さを測るのか－. 植物の光センシング－ 光情報の受容とシグナル伝達－. 細胞工学別冊 植物細胞工学シリーズ16．和田・徳富・長谷・長谷部 (監). 秀潤社. pp124-133．LINK

2000年

Izawa T, Oikawa T, Tokutomi S, Okuno K, Shimamoto K. (2000) Phytochromes confer the photoperiodic control of flowering in rice (a short-day plant). Plant J. 22:391-399. LINK

〜1999年

Enoki H, Izawa T, Kawahara M, Komatsu M, Koh S, Kyozuka J, Shimamoto K. (1999) Ac as a tool for the functional genomics of rice. Plant J.19:605-613. LINK

井澤 毅 (1999) 短日植物イネの光周性反応の分子メカニズム　　化学と生物植物の科学調節34: 294-298. LINK

Isshiki M, Morino K, Nakajima M, Okagaki RJ, Wessler SR, Izawa T, Shimamoto K. (1998) A naturally occurring functional allele of the rice waxy locus has a GT to TT mutation at the 5' splice site of the first intron. Plant J. 15:133-138. LINK

Kyozuka J, Konishi S, Nemoto K, Izawa T, Shimamoto K. (1998) Down-regulation of RFL, the FLO/LFY homolog of rice, accompanied with panicle branch initiation. Proc Natl Acad Sci U S A. 95:1979-1982. LINK

Izawa T and Shimamoto K. (1998) Ac/Ds as tools for rice molecular biology. Molecular biology of rice. Shimamoto (Ed). Springer. pp59-76.

Izawa T, Ohnishi T, Nakano T, Ishida N, Enoki H, Hashimoto H, Itoh K, Terada R, Wu C, Miyazaki C, Endo T, Iida S, Shimamoto K. (1997) Transposon tagging in rice. Plant Mol Biol.35:219-229. LINK

Ono A, Izawa T, Chua NH, Shimamoto K. (1996) The rab16B promoter of rice contains two distinct abscisic acid-responsive elements. Plant Physiol. 112 :483-491. LINK

Izawa T and Shimamoto K (1996) Becoming a model plant: The importance of rice to plant science. Trends in Plant Science 1:95-99. LINK

Izawa T, Foster R, Nakajima M, Shimamoto K, Chua NH. (1994) The rice bZIP transcriptional activator RITA-1 is highly expressed during seed development. The Plant Cell 6:1277-1287. LINK

Foster R, Izawa T, Chua NH. (1994) Plant bZIP proteins gather at ACGT elements. FASEB J. 8:192-200. LINK

Izawa T, Foster R, Chua NH. (1993) Plant bZIP protein DNA binding specificity. J Mol Biol. 230:1131-1144. LINK

Shimamoto K, Miyazaki C, Hashimoto H, Izawa T, Itoh K, Terada R, Inagaki Y, Iida S. (1993) Trans-activation and stable integration of the maize transposable element Ds- cotransfected with the Ac- transposase gene in transgenic rice plants. Mol Gen Genet. 239:354-360. LINK

Hayakawa T, Zhu Y, Itoh K, Kimura Y, Izawa T, Shimamoto K, Toriyama S. (1992) Genetically engineered rice resistant to rice stripe virus, an insect-transmitted virus. Proc Natl Acad Sci U S A. 89:9865-9869. LINK

Kyozuka J, Fujimoto H, Izawa T, Shimamoto K. (1991) Anaerobic induction and tissue-specific expression of maize Adh1 promoter in transgenic rice plants and their progeny. Mol Gen Genet. 228:40-48. LINK

Izawa T, Miyazaki C, Yamamoto M, Terada R, Iida S, Shimamoto K. (1991) Introduction and transposition of the maize transposable element Ac in rice (Oryza sativa L.). Mol Gen Genet. 227:391-396. LINK

Kyozuka J, Izawa T, Nakajima M, Shimamoto K (1990) Effect of the promoter and the first intron of maize Adh1 on foreign gene expression in rice Maydica 35: 353-357. LINK

Shimamoto K, Terada R, Izawa T, Fujimoto H. (1989) Fertile transgenic rice plants regenerated from transformed protoplasts Nature 338: 274-276. LINK