Normal and Pathological Red Cell Physiology

Editorial: Inflammatory Mechanisms of Hemolytic Diseases. Sesti-Costa R, Silva-Filho JL, Barcellini W, Le Van Kim C, Conran N. Front Immunol. 2022 Jan 12;12:834527. doi: 10.3389/fimmu.2021.834527. eCollection 2021.

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11. Lafage-Pochitaloff M, Gerby B, Baccini V, Largeaud L, Fregona V, Prade N, Juvin PY, Jamrog L, Bories P, Hébrard S, Lagarde S, Mansat-De Mas V, Dovey OM, Yusa K, Vassiliou GS, Jansen JH, Tekath T, Rombaut D, Ameye G, Barin C, Bidet A, Boudjarane J, Collonge-Rame MA, Gervais C, Ittel A, Lefebvre C, Luquet I, Michaux L, Nadal N, Poirel HA, Radford-Weiss I, Ribourtout B, Richebourg S, Struski S, Terré C, Tigaud I, Penther D, Eclache V, Fontenay M, Broccardo C, Delabesse E. Blood Adv. 2022 Jan 25;6(2):386-398. doi: 10.1182/bloodadvances.2021005311.

Platelet caspase-1 and Bruton tyrosine kinase activation in patients with COVID-19 is associated with disease severity and reversed in vitro by ibrutinib. Claude L, Martino F; Hermand P; Chahim BR, de Bourayne PM, Garnier Y, Tressieres B, Colin Y, Le Van Kim C, Romana M, Baccini V. Research Practice Thrombosis Haemostasis. 2022; 6(8):12811. DOI10.1002/rth2.12811

Strenuous exercise in warm environment is associated with improved microvascular function in sickle cell trait. Reminy K, Sock ETN, Romana M, Connes P, Ravion S, Henri S, Hue O, Hardy-Dessources MD, Antoine-Jonville S. Eur J App Physiol. 2022. 122(1):185-197. DOI10.1007/s00421-021-04821-2

Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis. Buks R, Dagher T, Rotordam MG, Alonso DM, Cochet S, Gautier EF, Chafey P, Cassinat B, Kiladjian JJ, Becker N, Plo I, Egee S, El Nemer W. Cells. 2022. 11(1):49. DOI10.3390/cells11010049

An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2(V617F) myeloproliferative neoplasms. Moraes GR, Pasquier F, Marzac C, Deconinck E, Damanti CC, Leroy G, El-Khoury M, El Nemer W, Kiladjian JJ, Raslova H, Najman A, Vainchenker W, Marty C, Bellanne-Chantelot C, Plo I. B J Haematol. 2022. 198(1):131-136. DOI10.1111/bjh.18165

Management of fetal and neonatal alloimmunization thrombocytopenia: About the Francophone working group on fetomaternal platelet alloimmunization. Winer N, Maisonneuve E, Debarge V, Levine E, Taillefer C, Petermann R, Bertrand G. J Gynecol Obstetric Human Reprod. 2022. 51(4):102345. DOI10.1016/j.jogoh.2022.102345

Plasma microparticles of intubated COVID-19 patients cause endothelial cell death, neutrophil adhesion and netosis, in a phosphatidylserine-dependent manner. Garnier Y, Claude L, Hermand P, Sachou E, Claes A, Desplan K, Chahim B, Roger PM, Martino F, Colin Y, Le Van Kim C, Baccini V, Romana M. Br J Haematol. 2022 Mar;196(5):1159-1169. doi: 10.1111/bjh.18019. Epub 2022 Jan 6.

Transmission electron microscopy to follow ultrastructural modifications of erythroblasts upon ex-vivo human erythropoiesis. Dussouchaud A, Jacob J, Secq C, Verbavatz JM, Moras M, Larghero J, Fader CM, Ostuni MA and Lefevre SD. Front Physiol. 2022 Feb 9;12:791691. doi: 10.3389/fphys.2021.791691. eCollection 2021 

Interactive Dynamics of Cell Volume and Cell Death in Human Erythrocytes Exposed to α-Hemolysin from Escherichia coli. Safiotti NA, Lauri N, Cane L, Gonzalez-Lebrero R, Alleva K, Mouro-Chanteloup I, Ostuni MA, Herlax V, Schwarzbaum PJ. Int. J. Mol. Sci. 2022, 23(2), 872; https://doi.org/10.3390/ijms23020872

HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia. O'Donohue MF, Da Costa LM, Lezzerini M, Unal S, Joret C, Bartels M, Brilstra E, Scheijde-Vermeulen M, Wacheul L, De Keersmaecker K, Vereecke S, Labarque V, Saby MJ, LeFevre SD, Platon J, Montel-Lehry N, Laugero N, Lacazette E, van Gassen K, Houtkooper RH, Simsek-Kiper PO, Leblanc TM, Yarali N, Cetinkaya A, Akarsu NA, Gleizes PE, Lafontaine DLJ, MacInnes AW. Blood. 2022 Feb 25:blood.2021011846. doi: 10.1182/blood.2021011846

Very late intubation in COVID-19 patients: a forgotten prognosis factor? Camous L, Pommier JD, Martino F, Tressieres B, Demoule A, Valette M. Crit Care. 2022 Apr 2;26(1):89. doi: 10.1186/s13054-022-03966-6.

Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles. Alvarez CL, Chêne A, Semblat JP, Gamain B, Lapouméroulie C, Fader CM, Hattab C, Sévigny J, Denis MFL, Lauri N, Ostuni MA, Schwarzbaum PJ. Biochim Biophys Acta Biomembr. 2022 May 30:183980. doi: 10.1016/j.bbamem.2022.183980.

Proteomic analysis of neutrophils from patients with COVID-19. Romana M, Leduc M, Hermand P, Bruce J, Gautier EF, Martino F, Garnier Y, Baccini V,  Le Van Kim C. Br J Haematol. 2022 Jul 11. doi: 10.1111/bjh.18347.

Chronic inflammation persistence after regular blood transfusion therapy in sickle cell anemia. Dembélé AK, Hermand P, Missud F, Lesprit E, Holvoet L, Brousse V, Ithier G, Odievre MH, Benkerrou M, Le Van Kim C, Koehl B. Blood Adv. 2022 Jul 14; bloodadvances.2022007464. doi: 10.1182/bloodadvances.2022007464. 

Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells. Dupuis L, Chauvet M, Bourdelier E, Dussiot M, Belmatoug N, Le Van Kim C, Chene A, Franco M. Int. J. Mol. Sci. 2022, 23(14), 7640; doi.org/10.3390/ijms23147640

Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells. Rougé S, Genetet S, Leal Denis MF,  Dussiot  M,  Schwarzbaum PJ,  Ostuni MA, Mouro-Chanteloup I. Int J Mol Sci 2022 Aug 20; 23(16):9401. doi: 10.3390/ijms23169401.

Extracellular vesicles in Sickle Cell Disease: A Promising Tool. Lamarre Y, Nader E, Connes P, Romana M, Garnier Y. Bioengineering 2022 Sep 5;9(9):439. doi: 10.3390/bioengineering9090439

Exploring the link between GBA1 mutations and Dementia with Lewy bodies, A Mini-Review. Gaubert S, Hourregue C, Mouton-Liger F, Millot P, Franco M, Amar-Bouaziz E, Aarsland D, Hugon J, Paquet C. Neurosci Biobehav Rev. 2022 Sep 6:104856. doi: 10.1016/j.neubiorev.2022.104856. 

Severe cardiac involvement related to COVID 19 infection: A retrospective case serie. Pommier, JD, Martino F, Delamare F, Camous, L. Journal of Critical Care. 2022. doi10.1016/j.jcrc.2022.154133  

Determinants of severity in sickle cell disease. Rees DC, Brousse V, Brewin JN. Blood Rev. 2022 Nov;56:100983. doi: 10.1016/j.blre.2022.100983. Epub 2022 Jun 9.

Retinal atrophy and markers of systemic and cerebrovascular severity in homozygous sickle cell disease. Martin GC, Brousse V, Connes P, Grevent D, Kossorotoff M, Da Costa L, Bourdeau H, Charlot K, Boutonnat-Faucher B, Allali S, De Montalembert M, Bremond-Gignac D, Vidal PP, Robert MP. Eur J Ophthalmol. 2022 Nov;32(6):3258-3266. doi: 10.1177/11206721221090794.

Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial. Magrin E, Semeraro M, Hebert N, Joseph L, Magnani A, Chalumeau A, Gabrion A, Roudaut C, Marouene J,  Lefrere F, Diana JS, Denis A,  Neven B, Funck-Brentano I, Negre O, Renolleau S, Brousse V, Kiger L, Touzot F, Poirot C, Bourget P, El Nemer W, Blanche S, Tréluyer JM, Asmal M, Walls C, Beuzard Y, Schmidt M, Hacein-Bey-Abina S, Asnafi V, Guichard I, Poirée M, Monpoux F, Touraine P, Brouzes C, de Montalembert M, Payen E, Six E, Ribeil JA, Miccio A, Bartolucci P, Leboulch P, Cavazzana M. Nat Med. 2022 Jan;28(1):81-88. doi: 10.1038/s41591-021-01650-w.

Identification of an Alu-mediated 5.7-kb deletion of the LU gene in a pregnant Moroccan woman with anti-Lu3. Pedini P, Laget L, Izard C, Menanteau C, Beley S, Granier T, Picard C, Bailly P, Chiaroni J, Mazieres S, Peyrard T, Silvy M. Blood Transfus. 2022 Nov 4. doi: 10.2450/2022.0200-22. 

Delayed hemolytic transfusion reaction in children with sickle cell disease: first five-year retrospective study in mainland France.Falguière C, Allali S, Khazem B, Kamdem A, Arnaud C, Belloy M, Guitton C, Odièvre MH, Pertuisel S, Dumesnil C, Guillaumat C, Garrec N, Gauthier A, Mahe P, Soussan-Banini V, Le-Carrer L, Merlin E, David A, Pellegrino B, Paillard C, Brasme JF, Lagarde M, Pirenne F, Pondarre C. Haematologica. 2022 Nov 3. doi: 10.3324/haematol.2022.281050. 

Subamniotic Haemorrhage, a Possible New Presentation of Fetal and Neonatal Alloimmune Thrombocytopenia. Maisonneuve E, Winer N, Debarge V, Fuchs F, Makowski C, Petermann R, Bertrand G. Fetal Diagn Ther. 2022;49(7-8):368-382. doi: 10.1159/000526505. 

Sickle cell disease patients with COVID-19 in Guadeloupe: Surprisingly favorable outcomes. Bernit E, Romana M, Alexis-Fardini S, Tarer V, Roger PM, Doumdo L, Petras E, Charneau C, Tressières B, Dessources MDH, Etienne-Julan M. E J Haem. 2022 May 4;3(3):636-643. doi: 10.1002/jha2.449. 

Splenectomy in sickle cell disease: do benefits outweigh risks? Nardo-Marino A, Brousse V. Haematologica. 2022 Aug 4. doi: 10.3324/haematol.2022.281587. 

Erythrocyte type 1 equilibrative nucleoside transporter expression in sickle cell disease and sickle cell trait. British Journal of Haematology. Koehl B, Claude L, Reminy K, Tarer V, Baccini V,  Romana M,  Colin-Aronovicz Y , Damaraju VL, Sawyer M, Peyrard T,  Etienne-Julan M, Le Van Kim C, Azouzi S, Reininger L. Br J Haematology. 2022 Dec 40 doi.org/10.1111/bjh.18586,