Our laboratory proposes a highly specialized technical platform for the study of Red Blood Cells named “Red Cell Clinic”, which proposes a wide and comprehensive approach to study the morphological/rheological/adhesive/functional phenotype of normal and pathological RBCs. It is open to collaborative research with colleagues interested in Red Cell Physiology and erythroid physiopathology.

The platform equipment was acquired and renewed through active co-funding strategy to obtain funds from Inserm, Université Paris Cité, INTS, Université des Antilles, ANR, Région Ile de France, Région Antilles & the GR-Ex Labex.

Facilities in Paris:

a) intravital video microscopy and flow adhesion platform to assess adhesive interactions; b) microfluidic (in collaboration with from ENS Paris-Saclay) and microfiltration devices to assess mechanical properties of RBCs; c) Sid4Bio quantitative phase imager; d) ektacytometer, oxyscan-ektacytometer and flow cytometer for extensive phenotypic analysis of RBCs; e) stopped-flow spectrofluorometer for the analyses of rapid kinetics transport; f) confocal and inverted fluorescence microscopes; f) high performance computer cluster to simulate complexes molecular dynamics from the red cell membrane; g) highly specialized “ex vivo human spleen filtration”

Facilities in Guadeloupe (French Antilles):

Our team in Guadeloupe has largely participated in the acquisition and development of the “molecular biology platform”, dedicated to diagnosis and research at the Centre Hospitalier et Universitaire (CHU) of Pointe à Pitre. In addition, our team provided an Hemorheology platform (viscosimeter, Lorca ektacytometer, collaboration with the UA Faculty of Sports Sciences - STAPS) and a Center for Biological Resources (CRB) for DNA and other sample collections (both joint-use facilities open to the University Hospital).