Signal Transduction Lab | J. Garcia-Nafria

Lab members

Javier García Nafría, PI

I was born in Madrid and studied at the University of Alcalá de Henares and the Universidad Autónoma de Madrid (Biochemistry, 2007). For my PhD I moved to the York Structural Biology Laboratory (York, UK). I did two post-dcotral stays at the MRC Laboratory of Molecular Biology (Cambridge, UK) where I studied neuronal membrane proteins by combining biochemistry, biophysics and structural biology. My post-doctoral work revealed the architecture of the heteromeric AMPA receptors (Science, 2016) and the human serotonin 5-HT1B receptor bound to a G-heterotrimer of the Go type (Nature, 2018). During this time I also had industrial collaborations with MRC-T, MedImmune (AstraZeneca) and Sosei Heptares Therapeutics . In 2019 I moved to the Institute for Biocomputation and Physics of complex systems (BIFI, Universidad de Zaragoza) with a Jóvenes Investigadores project and a Ramón y Cajal contract. Our research group focuses on understanding signal transduction in neuronal cells and the mechanisms of current therapeutics against CNS disorders.

Angel García Aldea

Lab Manager

Angel did a degree in Biología Sanitaria (U. Alcalá de Henares), a Master in Neuroscience (U. Autónoma de Madrid) and PhD at the IIB “Alberto Sols” (CSIC-UAM). He then spent some time at the CNB (CSIC). Angel manages tissue culture and protein production, teaches new members as well as being involved in varios research projects.

Contact:XXX_at_unizar.es

Josep Argerich

Post-doctoral researcher

Josep did a PhD at the University of Barcelona. He is now focused in understanding orphan receptors.

Contact: jargerich_at_unizar.es

Daniel Muñoz Reyes

Post-doctoral researcher

Daniel did a PhD at the Instituto Blas Cabrera - CSIC. He is now focused in the application of cryo-electron microscopy to orphan GPCRs.

Contact: dmunoz_at_unizar.es

Sandra Arroyo Urea

Post-doctoral researcher

Sandra did a Biochemistry degree at the University of Granada and a Master in Biomedicine at the Universidad Autónoma de Madrid. Her work is focused in understanding the mode of action of dopaminergic drugs.

contact: sarroyo_at_unizar.es

Angela Carrión Antolí

PhD student

Ángela did a Biochemistry degree at the University of Murcia. Her work is focused on developing new tools for the study of membrane proteins as well as working of G protein promiscuity and biased signalling.

Contact: acarrion_at_unizar.es

Iris del Val García

PhD student

Iris did a Biotechnology degree at the University of Zaragoza. Her work is focused on the study of orphan G protein-coupled receptors.

Contact: idelval_at_unizar.es

Guillermo Gil Martín

PhD student

Guillermo did a Biotechnology degree and a Master in Biotechnology and Bioengineering at the Universidad Miguel Hernandez in Elche. His current work focuses on generating new ways to control GPCRs.

contact: g.gil_at_unizar.es

Marina Sanz Gracia

N3 Researcher

contact:

David García Cebollada

Undergraduate TFG student

Biotechnology undergraduate student at Unizar.

Motivational Hedgehog

He motivates team members during hard times.

Alumni

Adriana Tejero Dia. TFG student. Biotechnology degree student. 2025.

Laia Mata Rios. TFG student. Biotechnology degree student. 2025.

Andrea Lopez Gracia. UNIVERSA summer student. Biotechnology degree student. 2024.

Javier Castillo García. TFG student. Biotechnology degree student. 2024.

Kleopatra Pappadouli. Erasmus+ student from Greece. March - july 2023.

Andrés Gordo Ortiz. UNIVERSA summer student. Biotechnology degree student. 2022.

Jorge Mallor Franco. Researcher. 2021-2022

Nickolas McVay. Visiting student from the University of North Arizona. 2021-22.

Sofía Nadal Delgado. TFG student. 2020-21

Iris del Val García. TFG student, Beca Colaboración MICINN y estudiante UNIVERSA. 2020-21

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