Signal Transduction Lab
Cryo-Electron Microscopy: Moving Beyond X-ray Crystal Structures for Drug receptors and Drug development. (2019) García-Nafría J. and Tate CG. Annual Reviews in Pharmacology and Toxicology. 2020 Jan 6;60:51-71. doi: 10.1146/annurev-pharmtox-010919-023545.
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8. (2019)Herguedas B, Watson JF, Ho H, Cais O, García-Nafría J, Greger IH.Science. 2019 Mar 14. pii: eaav9011
Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go.(2018)García-Nafría J., Nehme R., Edwards P., Tate CG.Nature, 2018. 558 (7711). 620-62
Structure and organization of heteromeric AMPA-type glutamate receptors. (2016)Herguedas B*, García-Nafria J*, Cais O, Fernandez-Leiro R, Ho H, Krieger J, Greger IH. Science. 2016. Apr 29;352(6285):aad3873
IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly. (2016)García-Nafria J, Watson JF, Greger IH. Scientific Reports.. 2016 Jun 6;6:27459.
17 January 2021
Grateful to get a Instruct Pilot Study Award! We are happy to get seed funding to try high risk/high gain ideas!
21 December 2020
Our review is featured in The atlas of science: https://atlasofscience.org/cryo-electron-microscopy-in-drug-development/
16 October 2020
Congratulations to Iris del Val García for obtaining the undergrad research fellowship "beca de colaboración" to work in the lab. Exciting moments ahead!!
09 October 2020
We are grateful to the BBVA Leonardo Fundation for the Beca Leonardo a Investigadores y Creadores Culturales 2020. We will do our best!
17 June 2020
The arrestin work gets highlighted in the TV news, newspapers and radio.
10th September 2019
Opening day for the lab!!