Medical applications of microswarm

Small-scale robots for medical treatments like targeted cell/drug delivery and hypothermia recently emerged with high potential to revolutionize healthcare. In these approaches, carriers like magnetic microrobots and nanoparticles (MNPs) are injected into a vein and circulate in the bloodstream. A magnetic force is used to steer them within the vasculature and guide them to the desired location. This approach aims to generate an optimal concentration of curing agent, i.e., a level greater than the minimum required and lower than the harmful dose, at the target location in the body. For the treatment to be successful, the swarm control and implementation of these agents are most important. My main research objective is to design, fabricate and implement swarm robotics for small-scale medical robots. I am particularly interested in answering the following questions :

Lab-on-chip application for diagnosis using microrobots

Design of the magnetic carrier

Design and Control to achieve deep reign targeting

Reaching beyond anatomical barriers

Real-Time imaging of the carriers

Design and implementation of swarm robotics at small scale

Selected Journal Publications

1) H. Khaksar+, A. Moghanizadeh+, A. K. Hoshiar, "A novel non-invasive intervention for removing occlusions from shunts using an abrading magnetic microswarm," in IEEE Transactions on Biomedical Engineering, 2022 (+Equal contributors).

2) A. K. Hoshiar, S. Dadras Javan, T. A. Le, Mohammad Reza Hairi Yazdi, J. Yoon, “Studies on Aggregated Nanoparticles Steering during Deep Brain Membrane Crossing”, Nanomaterial, Vol. 11, no 10, 2021.

3) K. Abolfathi, M.R.H. Yazdi, and A. K. Hoshiar, “Studies of Different Swarm Modes for the MNPs Under the Rotating Magnetic Field”, IEEE Transactions on Nanotechnology, 19, 2020.

Conference Publications

1) B. W. Jarvis, R. Poli A. K. Hoshiar, Electromagnetic Actuation Scheme for Swarm of Magnetic Nanoparticles Steering in Multi-bifurcation. The International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), Toronto, 2022.

2) K. Abolfathi K, MRH Yazdi, A. K. Hoshiar, Predictable Therapeutic Microswarm Dispersion for Targeted Drug Delivery Application, Hamlyn Symposium on Medical Robotics, 2022.