Development and Regeneration Lab

Decoding Development, Regeneration, and Disease with Precision and Model Systems

In our lab, our primary interest lies in unravelling the molecular mechanisms that govern the intricate processes of development and physiological organ regeneration. This exploration spans a wide spectrum, ranging from microscopic cellular interactions to transformation of tissues on a larger scale. By employing diverse models, notably the zebrafish, we are actively deciphering the complex processes that underlie these phenomena, shedding light on how they work and their implications for understanding human growth and its associations with diseases.

Within this context, our deep focus centres on orchestrated gene expression patterns during development that guide coordinated cell proliferation and differentiation. Our ultimate aim is to dissect transitions steering cells from rapid proliferation to specialized differentiation and from quiescence to renewed cell cycle engagement. These regulatory events are critical for the establishment, maintenance, and repair of tissues and organs, and they underlie disruptions in conditions like cancer.

As our research evolves, these interconnected findings further enrich our comprehension of development and its intricate intersections with the etiology of ailments.