신정우

경력

EDUCATION

2000 - 2006 M.D., Yonsei University College of Medicine, Seoul, Korea

2007 - 2009 M.S., Medical engineering, Graduate School of Medicine, Yonsei University, Seoul, Korea

2010 - 2014 Ph.D., Dermatology, Graduate School of Medicine, Yonsei University, Seoul, Korea

PROFESSIONAL RECORD

2015 ~ 2019 Research Assistant Professor, Department of Dermatology, Yonsei University College of Medicine

2016 ~ 2018 Visiting Scholar, Department of Dermatology, Columbia University Medical Center, New York, USA

2019 ~ 2022 Assistant Professor, Department of Dermatology, CHA Bundang Medical Center

2023 ~ Associate Professor, Department of Dermatology, CHA Bundang Medical Center

주요 연구분야

1. 아토피피부염 피부-신경-면역 네트워크 연구

2. 마이크로바이옴에 의한 아토피피부염 임상 및 DRG의 변화

3. 아토피피부염 중개연구

4. 화장품 소재 발굴 연구

5. 염증성 피부질환 인공피부 모델 연구

6. 피부장벽 강화 화장품 적용 임상시험

주요 발표논문 (최근 5년)

1. Kim JH, Shin JU (co-1st), Kim SH, Noh JY, Kim HR, Lee J, Chu H, Jeong KY, Park KH, Kim JD, Kim HK, Jeong DH, Yong TS, Park JW, Lee KH. Successful transdermal allergen delivery and allergen-specific immunotherapy using biodegradable microneedle patches. Biomaterials. 2018 Jan;150:38-48

2. Shin JU, Kim JD, Kim HK , Kang HK , Joo C, Lee JH, Jeong DH, Song S, Chu H , Lee JS, Lee H, Lee KH. Biodegradable microneedle patch to increase penetration of topical steroid in prurigo nodularis. Eur J Dermatol. 2018 Feb 1;28(1):71-77

3. Shin JU, Kim SH, Noh JY, Kim JH, Kim HR, Jeong KY, Park KH, Lee J, Chu H, Lee JH, Yong TS, Park JW, Lee KH. Allergen-specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model. Allergy. 2018 Sep;73(9):1801-1811

4. Wen HC, Czarnowicki T, Noda S, Malik K, Pavel AB, Nakajima S, Honda T, Shin JU, Lee H, Chou M, Estrada Y, Zheng X, Xu H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E. Serum from Asian patients with atopic dermatitis is characterized by TH2/TH22 activation, which is highly correlated with nonlesional skin measures. J Allergy Clin Immunol. 2018 Jul;142(1):324-328

5. Lee YI, Lee JH, Kim DY, Chung KY, Shin JU (correspondence author). Comparative Effects of Topical 0.2% Sirolimus for Angiofibromasin Adults and Pediatric Patients with Tuberous Sclerosis Complex. Dermatology. 2018;234(1-2):13-22

6. Abaci HE, Coffman A, Doucet Y, Chen J, Jacków J, Wang E, Guo Z, Shin JU, Jahoda CA, Christiano AM. Tissue engineering of human hair follicles using a biomimetic developmental approach. Nat Commun. 2018 Dec 13;9(1):5301

7. Noh JY, U Shin JU (co-1st), Kim JH, Kim SH, Kim BM, Kim YH, Park S, Kim TG, Shin KO, Park K, Lee KH. ZAG Regulates the Skin Barrier and Immunity in Atopic Dermatitis. J Invest Dermatol. 2019 Aug;139(8):1648-1657

8. Jacków J, Guo Z, Hansen C, Abaci HE, Doucet YS, Shin JU, Hayashi R, DeLorenzo D, Kabata Y, Shinkuma S, Salas-Alanis JC, Christiano AM. CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells. Proc Natl Acad Sci U S A. 2019 Dec 9

9. Shin JU, Abaci HE, Herron L, Guo Z, Sallee B, Pappalardo A, Jackow J, Wang EHC, Doucet Y, Christiano AM. Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing. Sci Rep. 2020 Mar 5;10(1):4123.

10. Yang B, Ryu JS, Rim C, Shin JU (co-correspondence), Kwon MS. Possible role of arginase 1 positive microglia on depressive/anxiet y-like behaviors in atopic dermatitis mouse model. Arch Pharm Res. 2022 Jan 20

11. Mok, Boram, Kim, A-Ram, Baek, Seung Hwa, Ahn, Ji Hae, Seok, Seung Hui, Shin Jung U (co-correspondence), KIM DONG HYUN. Profilin-1 prevents psoriasis pathogenesis through IκBζ regulation. J Invest Dermatol (accepted).