Research Interests
Research Interests
We are studying the molecular basis of Antimicrobial Resistance (AMR) and searching for new drug targets against AMR. We are investigating the action mechanisms of an essential bacterial GTPase protein, CgtA (Obg), which could serve as a new drug target against AMR in various bacteria. For this, we use multiple molecular biological, biochemical, microbiological, structural biological, and computational tools. We are studying several bacteria, such as Mycobacteria, Vibrio, and Pseudomonas. Furthermore, we are exploring the action mechanisms of several novel proteins recently discovered in our lab.
On the other hand, we are conducting structure-function studies (cryo-EM) on certain plant viruses that cause significant economic losses in India and globally.