As it was mentioned in the previous section, persians were very active in medieval times in medical practice as well as to diagnose and cure different neurological disorders. Persians were also active in teaching medicine (They established the first whole hospital system in the world. known as of Gondishapur) and discovering new medical knowledge. For instance, Razi discovered seven cranial nerves 31 spinal nerves for the first time in human history and described the facial and cranial nerves anatomy in details in his book (Al-Hawi). Avicenna  also had wrote about spinal disorders in his Canon of medicine and he introduced therapies such a food, massage and surgery for spinal traumas. There are also interesting nervous system disecting pictures from Mansur ibn Ilyas (1380-1422 AD) (a persian anatomist) from his book of anatomy, Tashrih-i Mansuri (please see the photos in this page). Another important book is Zakhirey-e Khwarazmshahi (The Treasure of the Khwarazm Shah) which is Esmail Jorjani comprehensive textbook of medicine and it was written around AD 1112. It includes 10 books. In some sections of the books (Chapter 2, Pamphlet 3, Section 4, Book 1) there are detailed descriptions of the cranial nerves, for example there is descriptions that how the  nerves are originating from the brain and there are in seven pairs. And there are paths that these nerves are leaving the skull (from Shoja et al., Neurosurgery 2007). One more important disease is stroke (Sekteh in persian). Avicenna described most of the signs and symptoms of stroke as we know it today in details in his book and persian physicians introduced different herbal remedies to cure this issue.

Furthermore, first time in human history, paralysis and tremor was described in Ferdos-ol Hokame by Tabari.