Ongoing research lines:

Revealing new roles of peroxisomal fatty acid oxidation in metabolic physiology.

Funded by:

• A-EXP-161-UGR23 funded by Consejería de Universidad, Investigación e Innovación and by ERDF Andalusia Program 2021-2027

• PID2023-148498OA-I00 funded by Ministry of Science, Innovation, and Universities (Spain) and Spanish Research Agency

We are very interested in the role of dicarboxylic acids in metabolism. These metabolites are formed by omega-oxidation in liver and kidney. The fatty acid that serves as the foundation of the dicarboxylic acid is primarily metabolized in mitochondria by beta-oxidation. However, the major site for dicarboxylic acid metabolism by beta-oxidation is the peroxisome. There are a lot of unknown regarding dicarboxylic acids, that we have only begun to understand. We work hard in the lab to understand what role these metabolites play and how modulation of their metabolism in peroxisome affects metabolic homeostasis.