Interferon

Interferon alpha and beta

Mechanism of action:

  • Naturally occurring cytokine, reduces inflammatory response.
  • Interferon beta-1a alpha
  • Interferon alfa-interferon alpha-2 a is also a naturally occurring cytokine and increases the inflammatory response. It is used in the treatment of hepatitis C it is reported to also cause autoimmune disease.

Uses

  • Interferon beta 1 alpha using the treatment of CIDP. This note of choice truck for this use given better options are available.

Adverse events

  • Interferon beta 1 is well-tolerated. Sometimes causes skin reactions.
  • Interferon alpha-2 causes minor side effects such as fatigue, fever, malaise and myalgia and arthralgias.

Treatment regimens

  • Interferon beta 1: 22 to 44 mcg subcutaneously thrice a week.
  • Interferon alfa 2, 3 mu twice a week.