Mitosis

(and an understanding of the Cell Cycle)

Biology

Standards: SC.912.N.1.6, SC.912.L.14.6, SC.912.L.16.8, SC.912.L.16.14, SC.912.L.16.17

Textbook: Chapter 11

Mitosis

Essential Content

A. Cell Cycle (16.14)

1. Prokaryotic cell cycle

2. Eukaryotic cell cycle

3. Interphase (G0*, G1, S, G2)

4. Cell division (mitosis and cytokinesis)

5. Regulation of the Cell Cycle**

B. Process of Mitosis (Nuclear Division) (16.14)

1. Phases (Prophase, Metaphase, Anaphase, and Telophase)

2. Importance of Maintaining Chromosome Number

C. Mistakes in the Cell Cycle (16.8)

1. Mutations

2. Uncontrolled Cell Growth (P53)

3. Cancer (checkpoints)

D. Asexual Reproduction

1. Lack of genetic variation

Objectives

· Describe the role of mitosis in asexual reproduction, including how this process may contribute to or limit genetic variation.

· Review the importance and role of mitosis of a cell within in an organism.

· Relate specific events to specific stages of the cell cycle. (ALD)

· Predict and explain what is happening at the different stages of mitosis.

· Explain how mitosis forms new cells and its role in maintaining chromosome number during asexual reproduction and cell and body growth.

· Predict the effects of mistakes made in the process of mitosis in a cell on an organism.

· Explain the importance of cyclins and proteins in the role of cell growth.

· Assess how uncontrolled cell growth may result from mutations that affect the proteins that regulate the cell cycle.

Investigate ways to prevent cancer growth within the body

Vocabulary

Mitosis, Cell division, Asexual reproduction, Chromosome, Chromatin, Cell cycle, Genetic variation, Interphase, DNA replication, Cytokinesis, Prophase, Centromere, Chromatid, Centriole, Metaphase, Anaphase, Telophase, Spindle, Spindle fiber, Cell plate, Cancer, Tumor, Benign tumor, Malignant tumor, chemotherapy

Chromosomes

  • is DNA containing cell’s genetic code

  • Each chromosome has a matching pair (homologous) One from each parent.

  • During interphase, each chromosome copies itself.

The Cell Cycle:

Interphase, Mitosis (PMAT) and Cytokinesis

Mitosis

Cell Division - process by which a cell splits into two identical daughter cells. Occurs in two main phase:

  1. Mitosis – chromosomes separate into two new cells (see PMAT below)

  2. Cytokinesis- Separation of the cell membrane and cytoplasm

*remember the phases and what happens in each phase.

Cell cycle and Mitosis Videos

Study Guide for Types of Cell Division

***Disclaimer: Study guide does NOT include the specifics on the phases of Meiosis.

PLEASE review notes and additional web resources listed under Topic 13 Meiosis section.****

11.1 11.2 Cell division, cell cycle and mitosis.pdf
11.3 and 11.4 cell regulation&differentiation.pdf