Golden oldies: ten crystallography articles that we think must be read
Virtual labs: https://www.jove.com/science-education-library/45/macromolecules, https://www.asbmb.org/education/online-teaching/online-lab-work, https://www.labster.com/, https://www.macmillanlearning.com/college/us/solutions/lab-solutions/lab-simulations,
“Synchrotron radiation and powder diffraction ”, Book Chapter for the International Tables of Crystallography- Volume H: Powder Diffraction, chapter 2.2, 51-65, 2019, (available online), A. N. Fitch.
Α very nice review article "Protein X-ray Crystallography and Drug Discovery"
https://research.csiro.au/crystal/user-guide/protein-structure-via-crystallisation/
https://podcasts.ox.ac.uk/keywords/x-ray-crystallography
freely accessible online
"Crystallization Under Special and Physical Environments"
Guest Editor(s): Abel Moreno.
https://www.mdpi.com/.../special_physical_environments
All articles can be accessed freely online. For your convenience, we attach
below a consolidated table of contents. If you think it appropriate, we
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Pérez-Solis, R.; Gervacio-Arciniega, J.J.; Joseph, B.; Mendoza, M.E.;
Moreno, A. Synthesis and Characterization of a Monoclinic Crystalline Phase
of Hydroxyapatite by Synchrotron X-ray Powder Diffraction and Piezoresponse
Force Microscopy. Crystals 2018, 8(12), 458;
https://doi.org/10.3390/cryst8120458.
Views: 1258, Downloads: 998, Citations: 2, Altmetrics: 0
https://www.mdpi.com/2073-4352/8/12/458
Romero-Núñez, A.; González, G.; Romero-Ibarra, J.E.; Vega-González, A.;
Cruz-Jiménez, G.; Hernández-Cristóbal, O.; Zárraga-Núñez, R.A.;
Obregón-Herrera, A.; López-Romero, E.; Pedraza-Reyes, M.; Cuéllar-Cruz, M.
Synthesis of Bimetallic Nanoparticles of Cd<sub>4</sub>HgS<sub>5</sub> by
<i>Candida</i> Species. Crystals 2019, 9(2), 61;
https://doi.org/10.3390/cryst9020061.
Views: 808, Downloads: 687, Citations: 0, Altmetrics: 0
https://www.mdpi.com/2073-4352/9/2/61
Pérez, K.S.; Moreno, A. Influence of Pyruvic Acid and UV Radiation on the
Morphology of Silica-carbonate Crystalline Biomorphs. Crystals 2019, 9(2), 67;
https://doi.org/10.3390/cryst9020067.
Views: 1120, Downloads: 652, Citations: 1, Altmetrics: 0
https://www.mdpi.com/2073-4352/9/2/67
Cuéllar-Cruz, M.; Moreno, A. The Role of Calcium and Strontium as the Most
Dominant Elements during Combinations of Different Alkaline Earth Metals in
the Synthesis of Crystalline Silica-Carbonate Biomorphs. Crystals 2019, 9(8),
381;
https://doi.org/10.3390/cryst9080381.
Views: 1023, Downloads: 1116, Citations: 2, Altmetrics: 0
https://www.mdpi.com/2073-4352/9/8/381
Tanaka, T.; Tsuboi, C.; Aburaya, K.; Kimura, F.; Maeyama, M.; Kimura, T.
X-ray Single-Crystal Structural Analysis of a Magnetically Oriented
Monoclinic Microcrystal Suspension of α-Glycine. Crystals 2019, 9(11), 561;
https://doi.org/10.3390/cryst9110561.
Views: 609, Downloads: 734, Citations: 0, Altmetrics: 1
https://www.mdpi.com/2073-4352/9/11/561
Spiliopoulou, M.; Valmas, A.; Triandafillidis, D.-P.; Kosinas, C.; Fitch, A.;
Karavassili, F.; Margiolaki, I. Applications of X-ray Powder Diffraction in
Protein Crystallography and Drug Screening. Crystals 2020, 10(2), 54;
https://doi.org/10.3390/cryst10020054.
Views: 646, Downloads: 565, Citations: 1, Altmetrics: 2
https://www.mdpi.com/2073-4352/10/2/54
Gavira, J.A.; Otálora, F.; González-Ramírez, L.A.; Melero, E.; Driessche,
A.E.; García-Ruíz, J.M. On the Quality of Protein Crystals Grown under
Diffusion Mass-transport Controlled Regime (I). Crystals 2020, 10(2), 68;
https://doi.org/10.3390/cryst10020068.
Views: 531, Downloads: 357, Citations: 2, Altmetrics: 2
https://www.mdpi.com/2073-4352/10/2/68
Protein crystals for the delivery of biopharmaceuticals (review article)
EBooks available: https://www.pdfdrive.com/search?q=biochemistry&pagecount=&pubyear=&searchin=&page=2
Teaching resources- https://www.ebi.ac.uk/pdbe/training/teaching-materials?fbclid=IwAR3R9cUyXpbpx42qt5vkCDsate_CKcHTyMnAIYCgyY-1uAJHy89hvC6g6t0
Crystallography Made Crystal Clear, Third Edition: A Guide for Users of Macromolecular Models.
Powder Diffraction: Theory and Practice (Book available online)
Useful links regarding crystallization screening: https://hwi.buffalo.edu/high-throughput-crystallization-center/, https://hwi.buffalo.edu/high-throughput-crystallization-center/crystallization-research/, https://hwi.buffalo.edu/scientist-directory/snell/, http://xtalpred.godziklab.org/XtalPred-cgi/xtal.pl (This is a webserver that will compare you aa sequence to other previously crystallized proteins. The result will also suggest which parts of your protein should be removed (if there are disordered regions). Have in mind that a bad score does NOT mean that your protein will not crystallize.)
International Tables for Crystallography, Volume H: Powder diffraction, First online edition (2018) ISBN: 978-1-118-41628-0 doi: 10.1107/97809553602060000115, Editors C. J. Gilmore, J. A. Kaduk and H. Schenk
- The preface: https://it.iucr.org/Ha/pre4v0001/
- The table of contents: https://it.iucr.org/Ha/contents/
- The website for the International Tables for Crystallography: https://it.iucr.org
The list of contributors can be found at: https://it.iucr.org/Ha/contributors/
A very nice review on protein crystallization methods: https://drive.google.com/open?id=10APQ2i0B7JbHRMdGtFPmMTFFxPBnuIoG
UNESCO Director General introduces the International Year of Crystallography 2014 (French language)
Some Keynote lectures from the 9th International Conference of the Hellenic Crystallographic Association (HeCrA9), Patras, Greece.
Seminar at Univ. of Patras (22/02/2018): Dr. Manfred Weiss, "Crystallographic fragment- screening at the HZB". Slides available, Abstract: Fragments are small organic molecules, with molecular weights in the 200 Da range. Screening fragments for binding to biological macromolecules has been around for some time now and it has been promoted for the following two reasons: (i) with relatively few fragments, one can to cover a large chemical space and (ii) being rather small, fragments are amenable to optimization by simply enlarging them. Typically, binding fragments are identified by a cascade of biophysical methods and then further analyzed structurally by X-ray crystallography. The major pitfall of this approach is that pre-screening methods tend to disagree with each other in particular for weakly binding entities, which fragments typically are. Consequently, pre-screening seems little effective and leads at best to an enrichment of potential binding hits. On the other hand, recent advances in synchrotron technologies, X-ray detectors and automated processing of diffraction data have made it possible to collect and process in excess of several hundreds of diffraction data sets per day. This level of throughput has made it possible to use the method X-ray crystallography as a (or the) primary screening technique. In the talk, I will discuss a large fragment-screening study (361 compounds vs. the protease endothiapepsin), as well as some results using a new small, affordable and versatile compound library, which we have recently assembled at the HZB and which is available to the HZB-MX beamline users. Further, I will show the MX-facilities at the HZB, including a new X-ray crystallography beam line dedicated to fragment screening experiments, which is currently being completed at the BESSY II synchrotron. Finally, in order to facilitate high-throughput crystallography I will also show an example for the efficient identification of fragment hits.
https://www.iitk.ac.in/tkic/workshop/XRD/ppt/Prof%20Rajesh/crystallography.pdf
Excellent lecture by Nobel prize winner Richard Henderson https://www.youtube.com/watch?v=p98JYaHaDC4&feature=youtu.be
X-ray Diffraction in simple words.
Protein Crystallography (N. Glykos), https://utopia.duth.gr/glykos/pdf/Protein_crystallography.pdf; https://www.openbook.gr/mia-mi-mathimatiki-eisagwgi-stin-krystallografia-proteinwn/
Postgraduate certificate course in Protein Crystallography via the web at Birkbeck. Information on registration and course content can be found at: http://px17.cryst.bbk.ac.uk/px/course/course.htm under "General course information" or contact Tracey Barrett at px@mail.cryst.bbk.ac.uk for further details.
For more details, please see http://www.bbk.ac.uk/study/2017/postgraduate/programmes/TMSBISCL_C/
Protein Crystallization by Terese Bergfors- https://xray.teresebergfors.com/tutorials/
Software for Macromolecule analysis http://kinemage.biochem.duke.edu/
TargetTrack, a target registration database, provides information on the experimental progress and status of targets selected for structural determination by the Protein Structure Initiative and other worldwide high-throughput structural biology projects, http://sbkb.org/tt/
Crystallography Open Database http://www.crystallography.net/cod/
International Year of Crystallography- IYCr2014: Educational material
Understanding Crystallography - Part 1: From Proteins to Crystals
Understanding Crystallography - Part 2: From Crystals to Diamond
https://www1.aps.anl.gov/Education/Powder-Diffraction-Century-Symposium
Lectures presented at the International Workshop on Powder and Electron Crystallography (2013, Patras, Greece).