2025 Publications
Zheng X, Sabouri M, Irwin BJ, Bernardo J, Machin DR. TcMAC21 mouse model of Down syndrome exhibits abnormal vascular physiology observed in people with Down syndrome. Physiology. 40(S1): 0181, 2025. https://doi.org/10.1152/physiol.2025.40.S1.0181
Sabouri M, Zheng X, Irwin BJ, Li Z, Samarah L, Berg Sen J, Bernardo J, Machin DR. Major physiological differences exist between C57BL/6 substrains. Physiology. 40(S1): 0326, 2025. https://doi.org/10.1152/physiol.2025.40.S1.0326
Lee MD, Osborne C, Stevenson R, MacDonald A, Ebner G, Jeffrey DA, MacDonald MA, Zhang X, Buckley C, Dabertrand F, Machin DR, Au J, Harraz OF, Tykocki N, McCarron JG, Wilson C. VasoTracker 2: An open-source platform for quantitative analysis of vascular reactivity and function. bioRxiv. 2025. https://doi.org/10.1101/2025.04.23.648411
Zheng X, Sabouri M, Irwin BJ, Bernardo J, Machin DR. TcMAC21 mouse model recapitulates abnormal vascular physiology observed in humans with Down syndrome. Physiological Reports. 13(11): e70384, 2025. PMID: 40474784. PMCID: PMC12141928. https://doi.org/10.14814/phy2.70384
Li Z*, Sabouri M*, Zheng X, Machin DR. Time course and contributors to greater glycocalyx thickness and integrity following Western diet consumption. American Journal of Physiology-Heart and Circulatory Physiology. 329(3): H765-H773, 2025. PMID: 40824919. PMCID: PMC1238320. https://doi.org/10.1152/ajpheart.00491.2025. Highlight: American Journal of Physiology-Heart and Circulatory Physiology. 330(1): H73-H74, 2026.
Machin DR, Islam MT, Malouf A, Nguyen D, Sabouri M, Boulos M, Horn AG, Schulze KM, Layec G, Lesniewski LA, Donato AJ. Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity. Aging. 17(9): 2335-2350, 2025. PMID: 40892009. PMCID: PMC12517214. https://doi.org/10.18632/aging.206313
Gonzalez IY, Friberg L, Sabouri M, Machin DR. Automated quantification of aortic stiffness via modified pin myography. Undergraduate Pipeline Network Summer Research Experience 2025 Research Symposium. 2025.
Lee MD, Osborne C, Stevenson R, MacDonald A, Ebner G, Jeffrey DA, Macdonald MA, Zhang X, Buckley C, Dabertrand F, Machin DR, Au J, Harraz OF, Tykocki N, McCarron JG, Wilson C. VasoTracker 2: Open-source software and hardware for tracking blood vessel diameter and assessing vascular function. The Journal of Physiology. In press. PMID: 41110981. PMCID: PMCID in progress. https://doi.org/10.1113/JP289322
Sabouri M*, Li Z*, Zheng X, Machin DR. Western diet-induced endothelial glycocalyx remodeling is partially reversed by fasting. American Journal of Physiology-Heart and Circulatory Physiology. 329(5): H1278-H1286, 2025. PMID: 41071682. PMCID: PMC12573073. https://doi.org/10.1152/ajpheart.00700.2025 Highlight: American Journal of Physiology-Heart and Circulatory Physiology. 329(6): H1666-H1667, 2025.
Friberg L, Agado D, Machin DR. A new automated myograph technique reveals the tunica media is the main contributor to healthy aorta stiffness. University of New Mexico Community of Scholars Fall Research Day. 2025.