2022 Publications
Machin DR, Clifton HL, Wray DW, Frech TM, Donato AJ. Tetrahydrobiopterin administration augments exercise-induced hyperemia and endothelial function in patients with systemic sclerosis. Frontiers in Medicine. 8: 791689, 2022. PMID: 35083247. PMCID: PMC8784551. https://doi.org/10.3389/fmed.2021.791689
Zheng X, Deacon C, King AJ, Machin DR. Microcirculatory and glycocalyx properties are lowered by high salt diet but augmented by western diet in genetically heterogeneous mice. American Journal of Physiology-Heart and Circulatory Physiology. 322(2): H328-H335, 2022. PMID: 34995168. PMCID: PMC8799391. https://doi.org/10.1152/ajpheart.00656.2021
Gogulamudi VR, Machin DR, Henson GD, Lim J, Bramwell RC, Durrant JR, Donato AJ, Lesniewski LA. Sirt1 overexpression attenuates Western-style diet-induced aortic stiffening in mice. Physiological Reports. 10(9):e15284, 2022. PMID: 35561022. PMCID: PMC9101596. https://doi.org/10.14814/phy2.15284
Mankouski A, Miller TA, Dodson RB, Yu B, Yang Y, Liu J, Machin DR, Donato AJ, McKnight RA, Zinkhan EK. Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high-fat diet. Physiological Reports. 12(23):e15518, 2022. PMID: 36461654. PMCID: PMC9718947. https://doi.org/10.14814/phy2.15518
Medarev S, Machin DR, Da Costa A, Hernandez J, Auger L, Qasim M, Trupiano S, Clark R, Hendrickson D, Schaeffer M, Schaeffer H, Muller-Delp J. Microvascular function in skeletal muscle of adiponectin knockout mice. FASEB Journal. 36(S1): R5297, 2022. https://doi.org/10.1096/fasebj.2022.36.S1.R5297
Islam MT, Hall S, Bloom S, Bramwell RC, Dutson T, Tucker J, Kim J, Machin DR, Donato AJ, Lesniewski LA. Ablation of Endothelial mTOR is benign in young mice and reverses age-related arterial and metabolic impairments in old mice. FASEB Journal. 36(S1): R6002, 2022. https://doi.org/10.1096/fasebj.2022.36.S1.R6002
Bloom S, Tucker J, Liu Y, Abdeahad H, Machin DR, Thomas T, Bramwell RC, Islam MT, Lesniewski LA, Donato AJ. Aging results in endothelial cell telomere uncapping that induces senescence and physiological dysfunction. FASEB Journal. 36(S1): R4606, 2022. https://doi.org/10.1096/fasebj.2022.36.S1.R4606
Machin DR, Deacon CL, King AJ, Zheng X. The effects of high salt and western diets on microcirculatory and glycocalyx properties in genetically heterogeneous young mice. FASEB Journal. 36(S1): R5147. 2022. https://doi.org/10.1096/fasebj.2022.36.S1.R5147