2023 Publications
Reeve EH, Kronquist EK, Wolf JR, Lee B, Khurana A, Pham H, Cullen AE, Peterson JA, Meza A, Bramwell RC, Villasana L, Machin DR, Henson GD, Walker AE. Pyridoxamine treatment ameliorates large artery stiffening and cerebral artery endothelial dysfunction in old mice. Journal of Cerebral Blood Flow & Metabolism. 43(2): 281-295, 2023. PMID: 36189840. PMCID: PMC9903220. https://doi.org/10.1177/0271678X221130124
Zheng X, Li Z, Berg Sen J, Samarah L, Deacon CS, Bernardo J, Machin DR. Western diet augments metabolic and arterial dysfunction in a sex-specific manner in outbred, genetically diverse mice. Frontiers in Nutrition. 9: 1090023, 2023. PMID: 36687716. PMCID: PMC9853899. https://doi.org/10.3389/fnut.2022.1090023
Zheng X, Berg Sen J, Li Z, Sabouri M, Samarah L, Deacon CS, Bernardo J, Machin DR. High-salt diet augments systolic blood pressure and induces arterial dysfunction in outbred, genetically diverse mice. American Journal of Physiology-Heart and Circulatory Physiology. 324(4): H473-483, 2023. PMID: 36735405. PMCID: PMC10010918. https://doi.org/10.1152/ajpheart.00415.2022
Machin DR, Trott DW, Gogulamudi VR, Islam MT, Vink H, Lesniewski LA, Donato AJ. Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction. GeroScience. 45(4): 2351-2365, 2023. PMID: 36787090. PMCID: PMC10651573. https://doi.org/10.1007/s11357-023-00745-1
Renteria LI, Zheng X, Valera I, Machin DR, Garcia CK, Leon LR, Laitano O. Ovariectomy aggravates the pathophysiological response to exertional heat stroke in mice. Journal of Applied Physiology. 134(5): 1224-1231, 2023. PMID: 37022961. PMCID: PMC10151055. https://doi.org/10.1152/japplphysiol.00092.2023
Lim J, Machin DR, Donato AJ. The role of hyaluronan in endothelial glycocalyx and potential preventative lifestyle strategy with advancing age. Current Topics in Membranes. 91: 139-156, 2023. PMID: 37080678. PMCID: PMC10464581. https://doi.org/10.1016/bs.ctm.2023.02.006
Bloom SI, Liu Y, Tucker JR, Islam MT, Machin DR, Abdeahad H, Thomas TG, Bramwell RC, Lesniewski LA, Donato AJ. Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments. Aging Cell. E13875, 2023. PMID: 37259606. PMCID: PMC10410008. https://doi.org/10.1111/acel.13875
Zheng X, Machin DR. Patching up a degraded endothelial glycocalyx in sepsis. American Journal of Physiology-Heart and Circulatory Physiology. 325(4): H673-H674, 2023. PMID: 37594482. PMCID: PMC10659260. https://doi.org/10.1152/ajpheart.00499.2023
Bloom SI, Tucker JR, Machin DR, Abdeahad H, Adeyemo AO, Thomas TG, Bramwell RC, Lesniewski LA, Donato AJ. Reduction of double-strand DNA break repair exacerbates vascular aging. Aging. 15(19): 9913-9947, 2023. PMID: 37787989. PMCID: PMC10599741. https://doi.org/10.18632/aging.205066
Machin DR, Sabouri M, Zheng X, Donato AJ. Therapeutic strategies targeting the endothelial glycocalyx. Current Opinion in Clinical Nutrition & Metabolic Care. 26(6): 543-550, 2023. PMID: 37555800. PMCID: PMC10592259. https://doi.org/10.1097/mco.0000000000000973
Zheng X, Berg Sen J, Li Z, Sabouri M, Samarah L, Deacon CS, Bernardo J, Machin DR. High-salt diet augments systolic blood pressure and induces arterial dysfunction in outbred, genetically diverse mice. Physiology. 38(S1): 5727696, 2023. https://doi.org/10.1152/physiol.2023.38.S1.5727696
Machin DR, Berg Sen J, Li Z, Sabouri M, Samarah L, Deacon CS, Bernardo J, Zheng X. Outbred, UM-HET3 mice have greater metabolic and arterial function than inbred, C57BL/6J mice. Physiology. 38(S1): 5763061, 2023. https://doi.org/10.1152/physiol.2023.38.S1.5763061
Renteria LI, Zheng X, Garcia CK, Machin DR, Laitano O. Ovariectomy increases intestinal damage post exertional heat stroke in mice. Medicine & Science in Sports & Exercise. 55(9S): 977, 2023. https://doi.org/10.1249/01.mss.0000988936.16030.87