PRISM Lab

We are PRISM Lab

Our research objective is to comprehensively analyze intricate signaling networks within the various cell types of the oral & maxillofacial region. To achieve this, we have developed and applied innovative single-cell-based approaches tailored to a wide range of biological scenarios, with a particular focus on host-microbe interactions. The novel insights garnered from our research serve as a critical foundation for the advancement of therapeutic strategies targeting a diverse diseases in medicine and dentistry.

Our Research & Projects

Recent Publications

S Jeong†*, SY Park†*, H Ku, BS Eom, D Kim#, JM Kim#, Fibronectin-guided immune-stromal cell crosstalk promotes angiogenesis in pulp-dentin complex regeneration. Experimental & Molecular Medicine, 2026 (Accepted) 

K Nam*, BS Eom*, JY Kim, MG Lee, JM Lee, K Lee, JK Cha, JM Kim#, S Lee#, SJ Kim#, Integrative genomic analysis of 21 orofacial diseases identifies novel risk loci and shared genetic architecture with systemic diseases. Nature Communications, 2026. 

S Jeong*, JK Cha*, W Ahmed*, J Kim, M Kim, KT Hong, W Choi, S Choi, TH Yoo, HJ An, SC An, J Lee, J Choi, SY Kim, JS Lee, S Lee#, J Choi#, JM Kim#. Development of MDM2-targeting PROTAC for Advancing Bone Regeneration. Advanced Science, 2025. 

SY Park*, D Kim*,  JW Jung, HJ An,  J Lee, Y Park, D Lee, S Lee#,  JM Kim#*. Targeting class A GPCRs for hard tissue regeneration. Biomaterials, 2023.

JW Jung, SY Park, EJ Seo, IH Jang, Y Park, D Lee, D Kim#,  JM Kim#. Functional expression of oxytocin receptors in pulp-dentin complex. Biomaterials, 2023.