Simple explanation of the creatinine blood test and what the numbers mean. Learn normal ranges, causes of high creatinine, and how it relates to kidney function in easy-to-understand language.
If you’ve had kidney labs done, one of the main numbers on your report is creatinine.
It’s one of the most important tests used to check how well your kidneys are working.
This page explains what creatinine means in simple, clear terms.
Creatinine is a waste product made by your muscles.
Your body produces it naturally every day as part of normal muscle activity.
Healthy kidneys remove creatinine from your blood and get rid of it in urine.
So:
👉 Creatinine is used as a measure of how well your kidneys are filtering.
Doctors check creatinine to help answer one main question:
Are the kidneys cleaning the blood properly?
If creatinine builds up in the blood, it can mean the kidneys are not filtering as well as they should.
Normal ranges can vary slightly by lab, but in general:
Adult women: about 0.5 – 1.1 mg/dL
Adult men: about 0.6 – 1.3 mg/dL
Your personal “normal” can depend on:
age
body size
muscle mass
overall health
That’s why one number alone doesn’t tell the whole story.
A higher-than-normal creatinine level can mean:
the kidneys are not filtering well
you may be dehydrated
a medication is affecting the kidneys
there is a temporary kidney problem
there could be chronic kidney disease
One high result does not automatically mean permanent kidney damage.
Low creatinine is usually not a kidney problem.
It can happen in people who:
have low muscle mass
are older
are very small in body size
are malnourished
Low creatinine by itself is rarely a medical concern.
Common reasons include:
dehydration
kidney infection
kidney stones
certain medications
high blood pressure
diabetes
heavy exercise before testing
recent illness
Some causes are temporary and reversible.
Creatinine is the main number used to calculate eGFR (estimated kidney function).
So:
Higher creatinine → usually lower GFR
Lower creatinine → usually higher GFR
That’s why these two tests are almost always looked at together.
Creatinine is measured with a simple blood test.
No special preparation is usually needed, although your doctor may ask you to:
avoid heavy exercise before testing
stay well hydrated
review medications
If your creatinine is higher than expected, your doctor may:
repeat the test
check a urine test
calculate your GFR
review your medications
look for dehydration or illness
Often the test is repeated before any diagnosis is made.
Can drinking water lower creatinine?
If you are dehydrated, yes — better hydration can improve results.
Can medications raise creatinine?
Yes. Some blood pressure medicines, pain relievers, and antibiotics can affect levels.
Does exercise affect creatinine?
Heavy exercise right before labs can sometimes cause a temporary rise.
Is one high creatinine result serious?
Not usually. Doctors often repeat the test to confirm.
Get medical help right away if high creatinine comes with:
very little urine
severe swelling
confusion
shortness of breath
chest pain
These can be signs of a serious kidney problem.
To better understand related results, see: