The WHIH Newscast and Roxxon Corporation are seen at various points in the series.

Samuel L. Jackson returns to play Nick Fury in Agents Of S.H.I.E.L.D. Season 1.

At some points in the early seasons of the series, Culver University is mentioned, the place where Bruce Banner, Betty Ross, and Samuel Sterns studied.

In Agents Of S.H.I.E.L.D. Season 1, Phil Coulson mentions that Emil Blonsky is being held at The Fridge, a S.H.I.E.L.D. detention and storage facility.

Skye mentions Project Pegasus, previously mentioned in Iron Man 2.

Jaimie Alexander and Maximiliano Hernandez return to play Lady Sif and Jasper Sitwell, respectively, after their debut in the Thor movie.

In Agents Of S.H.I.E.L.D. Season 1, we meet Agent Antoine Triplett, the grandson of Gabe Jones, a member of the Howling Commandos.

Hayley Atwell, Neal McDonough, and Kenneth Choi return to reprise their roles as Peggy Carter, Dum Dum Dugan, and Jim Morita, respectively, in a flashback scene from Agents Of S.H.I.E.L.D. Season 2.

The Red Skull is mentioned multiple times throughout the series.

Cobie Smulders returns to play Maria Hill in Agents Of S.H.I.E.L.D. Season 1 and Season 2.

Powers Boothe returns to play Gideon Malick, a member of the World Security Council who is secretly a member of Hydra, since his debut in The Avengers as one of the villains in Season 3.

Audrey Nathan makes her debut in Agents Of S.H.I.E.L.D. Season 1, after being mentioned by Phil Coulson in The Avengers.

Phil Coulson uses the same Destroyer Armor Prototype Gun he used in Loki with John Garrett.

Phil Coulson's death and subsequent resurrection are mentioned multiple times throughout the series.

The Chitauri invasion of New York is mentioned multiple times in the early seasons.

Agent Jemma Simmons contracts a contagious virus due to her contact with a Chitauri head that firefighters preserved after the Battle of New York.

In Agents Of S.H.I.E.L.D. Season 2, it is mentioned that agents Isabelle Hartley and Idaho were on the Budapest mission with Hawkeye and Black Widow.

In Agents Of S.H.I.E.L.D. Season 7, young John Garrett mentions Loki stabbing Coulson.

Titus Welliver returns to play Felix Blake in Agents Of S.H.I.E.L.D. Season 1 and Season 3.

The Centipede Prosthesis contains Aldrich Killian's Extremis Serum, previously seen in Iron Man 3.

William Sadler returns to play President Matthew Ellis in Agents Of S.H.I.E.L.D. Season 2 and Season 3.

In Agents Of S.H.I.E.L.D. Season 1, we meet Lorelei, a sorceress prisoner who escaped after the breakout in Asgard.

In Agents Of S.H.I.E.L.D. Season 1, Coulson's team must clear the debris from the Battle of Greenwich.

The final episodes of Agents Of S.H.I.E.L.D. Season 1 deals with the infiltration of Hydra members into S.H.I.E.L.D.

Alexander Pierce starts to secretly release and recruit Hydra operatives back in 1989, after he becomes an Undersecretary of the World Security Council.

Agent Eric Koenig asserts that Coulson's team is not colluding with Hydra by asking several questions, one of which was whether they had contact with Alexander Pierce.

In Agents Of S.H.I.E.L.D. Season 2, Kara Palamas and Sunil Bakshi use the Photostatic Veil, also used by Black Widow.

In the final episodes of Agents Of S.H.I.E.L.D. Season 1, we see Maria Hill having a conversation with Melinda May about her new job at Stark Industries after the fall of S.H.I.E.L.D., this after Hill had a call with Pepper Potts.

Dr. List mentions that Strucker has experimented on individuals with Loki's scepter.

In Agents Of S.H.I.E.L.D. Season 7, Hydra manages to create Project Insight years earlier, thanks to the help of the Chronicoms. The alternate Project Insight seen in season 7 targets Bruce Banner and Jim Morita.

The planet Xandar is mentioned a few times in Agents Of S.H.I.E.L.D. Season 5 and Season 6.

The gang war between Frank Castle and the rest of the gangs in Hell’s Kitchen is quickly referenced in a news crawl on Agents Of S.H.I.E.L.D. Season 3.

In Agents Of S.H.I.E.L.D. Season 2, Raina has a vision of the main events of Avengers: Age Of Ultron.

In the final episodes of Agents Of S.H.I.E.L.D. Season 2, Agent Gonzales accepts Coulson as director due to the help he provided to the Avengers in the Battle of Sokovia against Ultron.

In Agents Of S.H.I.E.L.D. Season 3, Daisy mentions the destruction of Sokovia.

In Agents Of S.H.I.E.L.D. Season 3, Coulson mentions to Fitz about the accident at Pym Tech.

In the final episodes of Agents Of S.H.I.E.L.D. Season 3, Coulson and May discuss Peggy Carter's death and the fight between Captain America and Iron Man.

The Sokovia Accords are mentioned several times in Agents Of S.H.I.E.L.D. Season 3 and Season 4.

In Agents Of S.H.I.E.L.D. Season 4 mentions the Vienna Attack caused by Bucky Barnes while he was controlled by Helmut Zemo, and that Jeffrey Mace was present at that event.

In Agents Of S.H.I.E.L.D. Season 4, a Watchdog tries to kill Jeffrey Mace with a Judas Bullet, previously seen in Luke Cage Season 1.

In Agents Of S.H.I.E.L.D. Season 4, we see that Robbie Reyes / Ghost Rider learned to open portals with his chains, just as the sorcerers of Kamar-Taj do with the Sling Rings.

In the Spider-Man: Homecoming movie, it is mentioned that the Department of Damage Control was still cleaning up the remains of the Triskelion, and later it appears rebuilt at the end of the Agents Of S.H.I.E.L.D. series.

In Agents Of S.H.I.E.L.D. Season 5, it is mentioned that there are Asgardians who have recently arrived in New York.

Ruby Hale's Chakram is made of Vibranium and bears many similarities to Nakia's Circular Blades.

In Agents Of S.H.I.E.L.D. Season 5, Daisy Johnson and Tony Caine subtly mention the Attack on New York in a conversation.

In the final episodes of Agents Of S.H.I.E.L.D. Season 5, Glenn Talbot sought to strengthen himself with more Gravitonium to defeat Thanos on the advice of The Confederation.

In Agents Of S.H.I.E.L.D. Season 7, Fitz and the team use the Quantum Realm to travel through time, just like the Avengers in Avengers: Endgame.