Therapeutic Approach
& Drug Development
Disease Models and Drug Development
Post-mortem brains from patients
Disease mouse model (AD, PD, DLB, etc.)
Human stem cells (Neurons, Microglia, Astrocytes) & Brain organoid
Genome-wide high-throughput screening (HTS) platform
Chemical library screening platform
Disease models and drug development are pivotal in the study and treatment of neurodegenerative diseases. Neurodegenerative diseases are characterized by the progressive loss of structure and function of neurons. Developing effective treatments for these conditions involves a deep understanding of their underlying mechanisms, which is greatly facilitated by various disease models.
Our laboratory aims at the development of effective therapeutic strategies. To achieve this, we utilize human samples such as post-mortem brains from patients and human stem cells, alongside disease mouse models. This dual approach ensures our research and drug development efforts are both relevant to real-world patient conditions and informed by detailed preclinical studies. Our goal is to create more effective therapeutic approaches and drug development pathways that closely align with the complexities of human neurodegenerative diseases.