Publications

Updated 2024 November

For the most recently updated publication list see google scholar page.

* denote shared co-authorship

# denote co-senior authorship

1. J. Kim, A. F. Kratz, S. Chen, J. Sheng, H. K. Kim, L. Zhang, B. K. Singh, A. Chavez, High-throughput tagging of endogenous loci for rapid characterization of protein function. Sci. Adv. 10, eadg8771 (2024). Video summary of manuscript.

2. J. Lee, J. Kim, H. Kim, H. Park, J. Y. Kim, E.-J. Kim, Y.-H. Yang, K.-Y. Choi, B.-G. Kim, Constructing multi-enzymatic cascade reactions for selective production of 6-bromoindirubin from tryptophan in Escherichia coli. Biotechnol. Bioeng. 119, 2938–2949 (2022).

3. H. Song, P.-G. Lee, J. Kim, J. Kim, S.-H. Lee, H. Kim, U.-J. Lee, J. Y. Kim, E.-J. Kim, B.-G. Kim, Regioselective one-pot synthesis of hydroxy-(S)-equols using isoflavonoid reductases and monooxygenases and evaluation of the hydroxyequol derivatives as selective estrogen receptor modulators and antioxidants. Front. Bioeng. Biotechnol. 10, 830712 (2022).

4. H. Song, P.-G. Lee, H. Kim, U.-J. Lee, S.-H. Lee, J. Kim, B.-G. Kim, Polyphenol-hydroxylating tyrosinase activity under acidic pH enables efficient synthesis of plant catechols and gallols. Microorganisms 9, 1866 (2021).

5. S.-J. Bae, S. Kim, H. J. Park, J. Kim, H. Jin, B.-G. Kim, J.-S. Hahn, High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate. Metab. Eng. 66, 68–78 (2021).

6. B. G. Park, J. Kim, E.-J. Kim, Y. Kim, J. Kim, J. Y. Kim, B.-G. Kim, Application of Random Mutagenesis and Synthetic FadR Promoter for de novo Production of ω-Hydroxy Fatty Acid in Yarrowia lipolytica. Front. Bioeng. Biotechnol. 9, 624838 (2021).

7. *J. Lee, *J. Kim, J. E. Song, W.-S. Song, E.-J. Kim, Y.-G. Kim, H.-J. Jeong, H. R. Kim, K.-Y. Choi, B.-G. Kim, Production of Tyrian purple indigoid dye from tryptophan in Escherichia coli. Nat. Chem. Biol. 17, 104–112 (2021).

8. J. Lee, J. Kim, H. Kim, E.-J. Kim, H.-J. Jeong, K.-Y. Choi, B.-G. Kim, Characterization of a tryptophan 6-halogenase from Streptomyces albus and its regioselectivity determinants. Chembiochem 21, 1446–1452 (2020).

9. K. Heo, Y.-H. Park, K.-A. Lee, J. Kim, H.-I. Ham, B.-G. Kim, W.-J. Lee, Y.-J. Seok, Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae. Nat. Commun. 10, 5358 (2019).

10. H.-W. Yoo, J. Kim, M. D. Patil, B. G. Park, S.-Y. Joo, H. Yun, B.-G. Kim, Production of 12-hydroxy dodecanoic acid methyl ester using a signal peptide sequence-optimized transporter AlkL and a novel monooxygenase. Bioresour. Technol. 291, 121812 (2019).

11. J. Kim, J. Lee, P.-G. Lee, E.-J. Kim, W. Kroutil, B.-G. Kim, Elucidating cysteine-assisted synthesis of indirubin by a flavin-containing monooxygenase. ACS Catal. 9, 9539–9544 (2019).

12. M. Kim, B. G. Park, E.-J. Kim, J. Kim, B.-G. Kim, In silico identification of metabolic engineering strategies for improved lipid production in Yarrowia lipolytica by genome-scale metabolic modeling. Biotechnol. Biofuels 12, 187 (2019).

13. S. Namgung, H. A. Park, J. Kim, P.-G. Lee, B.-G. Kim, Y.-H. Yang, K.-Y. Choi, Ecofriendly one-pot biosynthesis of indigo derivative dyes using CYP102G4 and PrnA halogenase. Dyes Pigm. 162, 80–88 (2019).

14. A. Hosseini-Abari, G. Emtiazi, M. Jazini, J. Kim, B. G. Kim, LC/MS detection of oligogalacturonic acids obtained from tragacanth degradation by pectinase producing bacteria. J. Basic Microbiol. 59, 249–255 (2019).

15. J. Lee, J. Yoo, J. Kim, Y. Jang, K. Shin, E. Ha, S. Ryu, B.-G. Kim, S. Wooh, K. Char, Development of multimodal antibacterial surfaces using porous Amine-reactive films incorporating lubricant and silver nanoparticles. ACS Appl. Mater. Interfaces 11, 6550–6560 (2019).

16. S.-M. Paik, J. Kim, E. Jin, N. L. Jeon, Overproduction of recombinant E. coli malate synthase enhances Chlamydomonas reinhardtii biomass by upregulating heterotrophic metabolism. Bioresour. Technol. 272, 594–598 (2019).

17. M. Kim, B. G. Park, J. Kim, J. Y. Kim, B.-G. Kim, Exploiting transcriptomic data for metabolic engineering: toward a systematic strain design. 54, 26–32 (2018).

18. P.-G. Lee, S.-H. Lee, J. Kim, E.-J. Kim, K.-Y. Choi, B.-G. Kim, Polymeric solvent engineering for gram/liter scale production of a water-insoluble isoflavone derivative, (S)-equol. Appl. Microbiol. Biotechnol. 102, 6915–6921 (2018).

19. W.-S. Song, H.-M. Park, J. M. Ha, S. G. Shin, H.-G. Park, J. Kim, T. Zhang, D.-H. Ahn, S.-M. Kim, Y.-H. Yang, J. H. Jeong, A. B. Theberge, B.-G. Kim, J. K. Lee, Y.-G. Kim, Discovery of glycocholic acid and taurochenodeoxycholic acid as phenotypic biomarkers in cholangiocarcinoma. Sci. Rep. 8, 11088 (2018).

20. J. Yoo, A. Birke, J. Kim, Y. Jang, S. Y. Song, S. Ryu, B.-S. Kim, B.-G. Kim, M. Barz, K. Char, Cooperative catechol-functionalized polypept(o)ide brushes and Ag nanoparticles for combination of protein resistance and antimicrobial activity on metal oxide surfaces. Biomacromolecules 19, 1602–1613 (2018).

21. J. Kim, H.-W. Yoo, M. Kim, E.-J. Kim, C. Sung, P.-G. Lee, B. G. Park, B.-G. Kim, Rewiring FadR regulon for the selective production of ω-hydroxy palmitic acid from glucose in Escherichia coli. Metab. Eng. 47, 414–422 (2018).

22. E. Jung, B. G. Park, H.-W. Yoo, J. Kim, K.-Y. Choi, B.-G. Kim, Semi-rational engineering of CYP153A35 to enhance ω-hydroxylation activity toward palmitic acid. Appl. Microbiol. Biotechnol. 102, 269–277 (2018).

23. J. Kim, P.-G. Lee, E.-O. Jung, B.-G. Kim, In vitro characterization of CYP102G4 from Streptomyces cattleya: A self-sufficient P450 naturally producing indigo. Biochim. Biophys. Acta Proteins Proteom. 1866, 60–67 (2018).

24. P.-G. Lee, J. Kim, E.-J. Kim, S.-H. Lee, K.-Y. Choi, R. J. Kazlauskas, B.-G. Kim, Biosynthesis of (-)-5-hydroxy-equol and 5-hydroxy-dehydroequol from soy isoflavone, genistein using microbial whole cell bioconversion. ACS Chem. Biol. 12, 2883–2890 (2017).

25. H.-J. Kim, S. Jang, J. Kim, Y.-H. Yang, Y.-G. Kim, B.-G. Kim, K.-Y. Choi, Biosynthesis of indigo in Escherichia coli expressing self-sufficient CYP102A from Streptomyces cattleya. Dyes Pigm. 140, 29–35 (2017).

26. B. G. Park, M. Kim, J. Kim, H. Yoo, B.-G. Kim, Systems biology for understanding and engineering of heterotrophic oleaginous microorganisms. Biotechnol. J. 12, 1600104 (2017).

27. E. Jung, B. G. Park, M. M. Ahsan, J. Kim, H. Yun, K.-Y. Choi, B.-G. Kim, Production of ω-hydroxy palmitic acid using CYP153A35 and comparison of cytochrome P450 electron transfer system in vivo. Appl. Microbiol. Biotechnol. 100, 10375–10384 (2016).

28. P.-G. Lee, J. Kim, E.-J. Kim, E. Jung, B. P. Pandey, B.-G. Kim, P212A mutant of dihydrodaidzein reductase enhances (S)-equol production and enantioselectivity in a recombinant Escherichia coli whole-cell reaction system. Appl. Environ. Microbiol. 82, 1992–2002 (2016).

29. C. Sung, E. Jung, K.-Y. Choi, J.-H. Bae, M. Kim, J. Kim, E.-J. Kim, P. I. Kim, B.-G. Kim, The production of ω-hydroxy palmitic acid using fatty acid metabolism and cofactor optimization in Escherichia coli. Appl. Microbiol. Biotechnol. 99, 6667–6676 (2015).

30. M. Kim, J. Sang Yi, J. Kim, J.-N. Kim, M. W. Kim, B.-G. Kim, Reconstruction of a high-quality metabolic model enables the identification of gene overexpression targets for enhanced antibiotic production in Streptomyces coelicolor A3(2). Biotechnol. J. 9, 1185–1194 (2014).

Patents

Updated 2024 November