Welcome to the Integrative Vascular Biology & Metabolism Lab (IVM Lab) at the IIT Dharwad. At the IVM Lab, we stand at the confluence of fluid dynamics, endothelial cell biology, vascular immunology and metabolic studies, embracing an interdisciplinary approach to unravel the complexities of cardiometabolic health and disease. Our research primarily focuses on the intricate interplay between blood flow dynamics and endothelial cell behavior-how the sheer forces and stress of blood movement can lead to endothelial reprogramming, influencing the onset and progression of cardiometabolic diseases and cancer. Delving deep into the mechanics of blood flow, our lab seeks to uncover how these physical forces not only shape the vascular environment but also trigger critical biochemical responses and metabolic changes within endothelial cells. By integrating advanced computational modeling with cutting-edge experimental techniques, transgenic animal models, we aim to illuminate the pathways through which flow-induced stress impacts cardiovascular metabolism and contributes to disease pathology. Through comprehensive exploration, our Lab aspires to develop innovative therapeutic strategies and diagnostic tools, paving the way for novel interventions in the treatment and prevention of cardiovascular diseases. Join us in our journey to decipher the mechanism of vascular remodeling and metabolism in pathophysiology of cardiovascular diseases.