Kreshnik is a Professor of Pharmaceutical Care and Pharmacy Informatics at the University of Prishtina, Faculty of Medicine, Kosovo. He completed his undergraduate and postgraduate PhD Pharmacy studies at Curtin University, Australia. At Curtin University Kreshnik also taught and coordinated various pharmacy practice and clinical pharmacy related courses. Kreshnik is specialized in Medication Management Reviews and as consultant pharmacist he has extensive experience in conducting comprehensive medication reviews in Western Australian community and residential aged care settings. Kreshnik is passionate about using technology to solve health related problems. He was awarded a Fulbright scholarship and spent a full postdoc academic year as Fulbright Scholar and was then employed as a Visiting Scientist at the Massachusetts Institute of Technology (MIT), Computer Science and Artificial Intelligence Laboratory. At MIT with his colleagues, Kreshnik explored the use of Artificial Intelligence (AI) and wireless signals as means of monitoring medication use.

Kreshnik co-invented a pain assessment method which led to the successful development of the world’s first Artificial Intelligence (AI)-powered pain assessment tool (now known as PainChek) used for people with communication difficulties such as those with dementia. As one of the co-inventors, Kreshnik independently consults in the capacity of a Senior Research Scientist at PainChek as this PainChek assessment system continues to be implemented in clinical practice in various countries including Australia, UK, Canada, New Zealand and now following recent FDA De Novo approval, in the US as well. His work in this area has extended to development of an AI-based solution for pain assessment in infants as well. Kreshnik's digital health-related research work has been published in leading journals including Nature Medicine and Lancet Digital Health. He serves as an Editorial Board member at IJCP and RSAP. He has recently completed guest editing pharmacy focused AI-special issues at IJCP and ERCSP and is now continuing to edit the new AI-special issue at IJPP.