Publications

PUBLICATIONS

1.     Mahmud I, Wei B, Veillon L, Tan L, Martinez S, Tran B, Raskind A, de Jong F, Akbani R, Weinstein JN, Beecher C, Lorenzi PL.  Ion suppression correction and normalization for non-targeted metabolomics. Nature Communications. (2025) 16:1347. (HILIC, RPLC, ICMS-based Metabolomics)

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2. Mahmud I3,11,*, Dazhi Wang1,2,*, Sze Kiat Tan1,2, Fatemeh Vatankhah1,4, Brianna E. Dessa1,2, Iva Vucic2, Valery Chavez Perez5, Mark L. Gonzalgo6,7, Oleksandr N. Kryvenko1,6,7,8, Vanina T. Tcheuyap9, James Brugarolas9,10, Jaime R. Merchan5,6, Timothy J. Garrett3, and Scott M. Welford1,6,. Lipidomic classification of clear cell Renal Cell Carcinoma (ccRCC) reveals aggressiveness and therapeutic sensitivity. Science Advances, 2025 (under review). *Equally contributing first author. (LCMS-based lipidomics)

3. Mahmud I1,4,5, Wai-Kin Chan1,4, Karen Yannell2, Cate Simmermaker2, Genevieve Van de Bittner2, Linfeng Wu2, Daniel Chan1, Sheher Moshin2, Yiwei Liu1, John Sausen2, John N. Weinstein1, and Philip L. Lorenzi1,3,5. Single-sample, multi-omic mass spectrometry for investigating mechanisms of drug toxicity. https://www.biorxiv.org/content/10.1101/2025.02.13.638125v1. J Proteome Res. 2025 Sep 5;24(9):4538-4546. (5Co-corresponding author). (LCMS-based metabolomics, lipidomics, and proteomics)

4. Mahmud I1&4*, Taylor A. Harmon2, Laurel E. Meke3, Timothy J. Garrett1,3*. Discrepancies in Biomarker Identification in Different Peak-Picking Strategies in Untargeted Metabolomics Analyses of Cells, Tissues, and Biofluids. https://www.biorxiv.org/content/10.1101/2025.03.04.641559v1. Journal of Proteome Res (under minor revision), 2025 (*Co-corresponding author). (LCMS-based metabolomics)

5.     Mahmud I2,13, Sandeep Das1,13, Sumit K Anand1,13, M Peyton McKinney1,13, Sumati Rohilla1, Koral S E Richard1, Fabio Arias1, Alia Ghrayeb1,3, Bo Wei2, Lin Tan2, Zhipeng Liu4, Dhananjay Kumar5, Alexandra C Finney1, Nilesh Pandey1, Harpreet Kaur1, Rajan Pandit4, Cyrine B Dhaou4, Sarah P Thayer6, Babak Razani7, Bishuang Cai8, Fei Chang9, Francisco J Schopfer9, Wanqing Liu10, Edward A Fisher11, Sridhar Radhakrishnan12, Eyal Gottlieb3, A Wayne Orr1,5, Nirav Dhanesha1, Arif Yurdagul Jr1,5, Philip L Lorenzi2,14, Oren Rom1,5,14,15. Sex-based multiomics analysis of concurrent MASH and atherosclerosis in mice. Journal of Hepatology reports (Under revision, 2025).  13Equally contributing first author.  (RPLC and ICMS-based multi-organ multiomics)

6. Mahmud I, Frederico G. Pinto, Timothy J. Garrett. Rapid noninvasive classification of prostatic disease using paper spray ionization mass spectrometry (PSI-MS)-based non-targeted metabolomics. Analytical chemistry (under review), 2025 (5Co-corresponding author). (PSI-MS-based metabolomics)

7.     Mahmud I1, Thomas LaRoche1, Mary Rohrdanz1, Chris Wakefield1, Faiza H. Waghu1, Bradley M. Broom1, Rehan Akbani1, and John N. Weinstein1#, Philip L. Lorenzi1,2#. xPEDITE: Multi-Omics Pipeline for Data Integration and Translational Exploration. Manuscript ready to submit for Nucleic acid Research, 2025. (Metabolomics raw data processing and analysis pipeline)

8. Li Qin1, Luz Yurany Moreno Rueda1, Upasana Ray1, Mahmud I2, Philip L. Lorenzi2, Suyu Liu3, Heather Lin3, Fenghuang Zhan4, David E. Mery4, David E. Symer1, Maria Jose Acevedo Calado1, Hua Wang1, Hans C. Lee1, Krina K. Patel1, Isere Kuiatse1, and Robert Z. Orlowski1,5. Targeting Caseinolytic Mitochondrial Matrix Peptidase, a Novel Contributor to High-risk Behavior, in Multiple Myeloma. Blood, 2024024781. (ICMS-based Metabolomics)

9.     Maria Angelica Freitas-Cortez1, Fatemeh Maspour1, Mahmud I2, Yue Lu3, Ailing Huang1, Lisa K. Duong1, Qi Wang4, Tiffany Voss1, Hong Jiang1, Claudia S. Kettlun1,6, Kevin Lin3, Jie Zhang5, Efrosini Tsouko7, Shonik Ganjoo1, Hampartsoum B. Barsoumian1, Thomas S. Riad1, Yun Hu1, Carola Leuschner1, Nahum Puebla-Osorio1, Jing Wang4, Jian Hu8, Michael A. Davies9, Vinay K. Puduvalli10, Cyrielle Billon11, Thomas P. Burris12, Philip L. Lorenzi2, Boyi Gan5, James Welsh1. Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins. Molecular Cancer, (2025) 24:40. (LCMS-based lipidomics)

10.  Carrie R. Daniel*1†, Yufan Qiu2†, Nazli Dizman3†, Yan Jiang2, Satabdi Saha4, Margaux Robert1, Rebecca A. Soto5, Zoey R. Neale5, Rachel M. Farias2, Erma J. Levy1, Cindy H. Hwang1, Brenda Melendez5, Ehsan Irajizad4, Samin Javanmardi2, Brooke S. L 5 ochmann2, Mahmud I6, Diana D. Shamsutdinova7, Davis R. Ingram7, Khalida Wani7, Mona M. Ahmed5, Lon W.R. Fong5, Bharat B. Singh5, Ashley E. Holly2, Laura E. Klein1, Ngoc-Trang Adrienne Nguyen2, Daniel C. Mousavi2, Ashish V. Damania5, Matthew C. Wong5, Abderrahman Day5, Aditya K. Mishra5, Elizabeth Sirmans2, Jared C. Malke8, Lin Tan6, Chia-Chi Chang5, Samuel A. Shelburne9, Philip L. Lorenzi6, Stephanie S. Watowich10, Jian Wang4, James P. Allison10, Padmanee Sharma11, Elizabeth M. Burton5, Jeffrey E. Gershenwald8, Alexander J. Lazar12, Cassian Yee2, Adi Diab2, Michael K. Wong2, Sapna P. Patel2, Alexandra P. Ikeguchi2, Isabella C. Glitza Oliva2, Hussein A. Tawbi2, Rodabe N. Amaria2, Michael A. Davies2, Lorenzo Cohen13, Christine B. Peterson4, Johannes F. Fahrmann14, Jennifer A. Wargo5,8‡, Nadim J. Ajami5‡, Jennifer L. McQuade2‡*. A high fiber dietary intervention promotes immunotherapy response in patients with melanoma. Science, adx6851 (Under revision). (LCMS-based metabolomics and lipidomics)

11.  Feiyu Chen, Haoyan Li, Yin Wang, Chenling Meng, Ximing Tang, Wei Shi, Javier Leo, Jie Zhang, Vivien Van, Mahmud I, Bo Wei, Philip L Lorenzi, Maria Gabriela Raso, Boyi Gan, Di Zhao.  CHD1 Loss hijacks SREBP2-mediated Cholesterol Biosynthesis to Energize SPOP-deficient Prostate Cancer and Drives Castration Resistance. Nat Cancer (2025). https://doi.org/10.1038/s43018-025-00952-z. (LCMS-based lipidomics)

12.  Yun Xiong, Lin Tan, Wai-kin Chan, Eric S. Yin, Sri Ramya Donepudi, Jibin Ding, Bo Wei, Sara Martinez, Mahmud I, Hamish I. Stewart, Daniel J. Hermanson, John N. Weinstein, Philip L. Lorenzi. Ultra-Fast Multi-Organ Proteomics Tissue-Specific Mechanisms of Drug Efficacy and Toxicity. Nature Commun, NCOMMS-25-30563-T (under revision), 2025, https://doi.org/10.1101/2024.09.25.615060. (ICMS-based metabolomics)

13.  Kaw A, Wu T, Starosolski Z, Zhou Z, Pedroza AJ, Majumder S, Duan X, Kaw K, Pinelo JEE, Fischbein MP, Lorenzi PL, Tan L, Martinez SA, Mahmud I, Devkota L, Taegtmeyer H, Ghaghada KB, Marrelli SP, Kwartler CS, Milewicz DM. Augmenting Mitochondrial Respiration in Immature Smooth Muscle Cells with an ACTA2 Pathogenic Variant Prevents Moyamoya-like Cerebrovascular Disease. Nat Commun. 2025 Jul 2;16(1):6105. (ICMS-based metabolomics)

14.  Caitlyn M. Gaffney, Angela M. Casaril, Mahmud I, Bo Wei, Karen M. Valadez, Elizabeth A. Kolb , Fisher R. Cherry, Theresa A. Guise, Philip L. Lorenzi, Lei Shi, Andrew J. Shepherd. Inflammatory Neuropathy in the MC38 Mouse Model of Colorectal Cancer. Nature Commun. 2024 (under minor revision), https://doi.org/10.1101/2024.07.19.604274. (LCMS-based lipidomics)

15.  Sivareddy Kotla1,15,17, Jonghae Lee1,2,15, Kyung Ae Ko1,15, Weiqing Chen3, 15, Venkatasubrahman K Samanthapudi1, Oanh Hoang1, Gilbert F. Mejia1, Shengyu Li3, Keri L. Schadler2, Luis Antonio Rivera1, Kay Carlene Tavares Samperio1, Jung Hyun Kim Choi1, Kelia Carolina Ostos Mendoza1, Anita Deswal1, John P. Cooke2, Keigi Fujiwara1, Nicolas L. Palaskas1, Efstratios Koutroumpakis1, Rajneesh Pathania4, Philip L. Lorenzi5, Lin Tan5, Mahmud I5, Laurent Yvan-Charvet6, Eduardo N. Chini7, Joerg Herrmann8, Ying H. Shen9, James F. Martin10, Haodong Xu11, Erin H Seeley12, Jared K. Burks13, Paul S. Brookes14, Guangyu Wang2,16,17,  Nhat-Tu Le2,16,17, Jun-ichi Abe1,16,17 . Downregulation of LATS1/2 Drives Endothelial Senescence-Associated Stemness (SAS) and Atherothrombotic Lesion Formation. Circulation, 2025 (Under review). (ICMS-based metabolomics)

16.  Victor Tatarskiy1,2*, Wai-Kin Chan3*, Lin Tan3, Alvina Khamidullina2, Mahmud I3, Shwetha V. Kumar5, Julia Nuzhina2, Sara A. Martinez3, Bao Q. Tran3, Anna Skwarska4, Nataliya Pavlenko1,2, Alena Dorofeeva1, Marina Konopleva4, Dmitry Genis1, John N. Weinstein3, Roman Kombarov1#, and Philip L. Lorenzi3,6#. The ASNS inhibitor ASX-173 potentiates L-asparaginase anticancer activity. Blood Advances, 2025 (Under review). (ICMS-based metabolomics)

17.  Alatawi H, Nair HH, Ai L, Mahmud I, Gour A, Singh A, Baek D, Yan B, Maharjan CK, Zhang W, Law BK, Zajac-Kaye M, Vulpe C, Guryanova OA, Sharma AK, Garrett TJ, Sharma A, Heldermon CD, Hong S, Narayan S. CerS2 is a druggable target in triple-negative breast cancer. Molecular Cancer  (Unver review), 2025 Aug 21:2025.08.15.670525. doi: 10.1101/2025.08.15.670525. PMID: 40894709.  (LCMS-based lipidomics)

18.  Patrick G. Pilié1, Elavarasan Subramani2, Rebecca Slack-Tidwell3, Paul Viscuse4, Dominik Awad2, Licai Zhang3, Christine Peterson3, Amado Zurita1, Sumit Subudhi1, Paul Corn1, Rama Soundararajan5, Peter Shepherd1, Nora M. Navone1, Badrajee Piyarathna6, Vasanta Putluri6, Nagireddy Putluri6, Arun Sreekumar6, Yuzhuo Wang7, Amina Zoubeidi7, Mahmud I8, Philip L. Lorenzi8, Sreyashi Basu9, Sonali Jindal9, Padmanee Sharma1,9, Christopher Logothetis1, Timothy C. Thompson1, Daniel E. Frigo1,2,10,11 , Ana Aparicio. Targeting arginine metabolism overcomes chemotherapy resistance in aggressive variant prostate cancer.  Cell Reports Medicine, 2025, CR-MEDICINE-D-25-03537, (Under review). (ICMS-based metabolomics)

19.  Haley Chatelaine1, Cristina Balcells Nadal2, Stephen Barnes3, Djawed Bennouna1, Justin Cross4, Clay Davis11, Felice de Jong5, Maureen Kachman6, Tim Garrett7, Hector Keun2, Mahmud I8, Wenqian Li7, Philip Lorenzi12, Robert Powers9,10, Alexander Raskind6, Michelle Saoi4, Tracey Schock11, Bo Wei8, Landon Wilson3, Chris Beecher5, Ewy A. Mathé1. Metabolomic profiles generated using the IROA TruQuant platform result in reproducible differentiation of sample mixtures in a multi-lab “round robin” study. Manuscript ready to submit to Nature Communications, 2025. (ICMS and HILIC-based metabolomics)

20.  Caleb Shi, Mahmud I, Philip Lorenzi, Jose Felix Moruno Manchon, Ana Palei, Jorge Salazar, Jacqueline G. Parchem, Akram Yazdani, Tina O. Findley. Manuscript ready to submit to Circulation, 2025. (LCMS-based lipidomics)

21.  Wang D, Mahmud I, Thakur VS, Tan SK, Isom DG, Lombard DB, Gonzalgo ML, Kryvenko ON, Lorenzi PL, Tcheuyap VT, Brugarolas J, Welford SM. GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma. Cancer Res. 2024 Apr 19. doi: 10.1158/0008-5472.CAN-23-2926. PMID: 38640229. (LCMS-based lipidomics)

22.  Xin Li a #, Maryam Elizondo a, Katherine Pham a, Jazmin Ysaguirre a, Mahmud Ib, Lin Tan b, Hiromi Sesaki c , Rabie Habib a,  Philip Lorenzi b, and Kai Sun. Unraveling the Multifaceted Metabolic Function of Dynamin-Related Protein 1 (Drp1) in Adipose Tissue. Journal of Lipid Research, 2024 August 25, https://doi.org/10.1016/j.jlr.2024.100633. PMID: 39182608. (LCMS-based lipidomics)

23.  Mishra AK, Mahmud I, Lorenzi PL, Jenq RR, Wargo JA, Ajami NJ, Peterson CB. TARO: tree-aggregated factor regression for microbiome data integration. Bioinformatics, btae321, 2024, May 24. https://doi.org/10.1093/bioinformatics/btae321. PMID: 38788190. (Microbiome, metabolomics, and  lipidomics)

24.  Sandeep Das1, Alexandra C Finney1, Sumit Kumar Anand1, Sumati Rohilla1, Yuhao Liu2, Nilesh Pandey1, Alia Ghrayeb1,3, Dhananjay Kumar4, Kelley Nunez5, Zhipeng Liu6, Fabio Arias7, Ying Zhao2, Brenna Pearson-Gallion1, M Peyton McKinney1, Koral S E Richard1, Jose A Gomez-Vidal7, Chowdhury S Abdullah1, Elizabeth D Cockerham1, Joseph Eniafe8, Andrew D Yurochko8, Tarek Magdy1, Christopher B Pattillo4, Christopher G Kevil1,4, Babak Razani9, Md Shenuarin Bhuiyan1,4, Gretchen E Galliano10, Bo Wei11, Lin Tan11, Mahmud I11, Ida Surakka2, Minerva T Garcia-Barrio2, Philip L Lorenzi11, Eyal Gottlieb3, Eduardo Salido12, Jifeng Zhang2, A Wayne Orr1,4, Wanqing Liu13, Monica Diaz-Gavilan7, Y. Eugene Chen2, Nirav Dhanesha1, Paul T Thevenot5, Ari J Cohen5,14, Arif Yurdagul Jr1,4, Oren Rom1,4. Genetic and pharmacological targeting of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis. Nature Metab. 2024 Sep 27. doi: 10.1038/s42255-024-01134-4. (LCMS-based metabolomics and lipidomics)

25.  Nicholas Blazanin, Xiaobing Liang, Mahmud I, Eiru Kim, Lin Tan, Nazanin Esmaeili Anvar, Waikin Chan, Min Jin Ha, Rosalba Minelli, Michael Peoples, Philip Lorenzi, Travar Hart, Yonathan Lissanu. Therapeutic modulation of rock overcomes metabolic adaption to oxphos inhibition and suppresses tumor growth. Nature Commun. 2024 (Under revision). DOI: 10.1101/2024.09.16.613317. (ICMS-based metabolomics)

26.  Chattopadhyay C, Roszik J, Bhattacharya R, Alauddin M, Mahmud I, Yadugiri S, Ali MM, Khan FS, Prabhu VV, Lorenzi P, Burton E, Morey RR, Lazcano R, Davies MA, Patel SP, Grimm EA. Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma. British Journal of Cancer. PMID: 38293232. (LCMS-based metabolomics and lipidomics)

27.  Schwartz-Duval AS, Mackeyev Y, Mahmud I, Lorenzi PL, Gagea M, Krishnan S, Sokolov KV. Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS Nano. 2024 Jan 23;18(3):1865-1881. doi: 10.1021/acsnano.3c04260. Epub 2024 Jan 11. PMID: 38206058. (ICMS-based metabolomics)

28.  Lee H, Horbath A, Kondiparthi L, Meena JK, Lei G, Dasgupta S, Liu X, Zhuang L, Koppula P, Li M, Mahmud I, Wei B, Lorenzi PL, Keyomarsi K, Poyurovsky MV, Olszewski K, Gan B. Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature Commun. 2024 Jan 2;15(1):79. doi: 10.1038/s41467-023-44412-7.PMID: 38167301. (LCMS-based lipidomics)

29.  Mahmud I, Tian G, Wang J, Hutchinson TE, Kim BJ, Awasthee N, Hale S, Meng C, Moore A, Zhao L, Lewis JE, Waddell A, Wu S, Steger JM, Lydon ML, Chait A, Zhao LY, Ding H, Li JL, Purayil HT, Huo Z, Daaka Y, Garrett TJ, Liao D. DAXX drives de novo lipogenesis and contributes to tumorigenesis. Nature Commun. 2023 Apr 12;14(1):1927.   (LCMS-based lipidomics)

30.  Yuan M, Mahmud I, Katsushima K, Joshi K, Saulnier O, Pokhrel R, Lee B, Liyanage W, Kunhiraman H, Stapleton S, Gonzalez-Gomez I, Kannan RM, Eisemann T, Kolanthai E, Seal S, Garrett TJ, Abbasi S, Bockley K, Hanes J, Chapagain P, Jallo G, Wechsler-Reya RJ, Taylor MD, Eberhart CG, Ray A, Perera RJ. miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene ACSL4 (long-chain acyl-CoA synthetase 4). Acta Neuropathol Commun. 2023 Dec 19;11(1):203. doi: 10.1186/s40478-023-01684-w.PMID: 38115140. (LCMS-based metabolomics and lipidomics)

31.  Colbert LE, El Alam MB, Wang R, Karpinets T, Lo D, Lynn EJ, Harris TA, Elnaggar JH, Yoshida-Court K, Tomasic K, Bronk JK, Sammouri J, Yanamandra AV, Olvera AV, Carlin LG, Sims T, Delgado Medrano AY, Napravnik TC, O'Hara M, Lin D, Abana CO, Li HX, Eifel PJ, Jhingran A, Joyner M, Lin L, Ramondetta LM, Futreal AM, Schmeler KM, Mathew G, Dorta-Estremera S, Zhang J, Wu X, Ajami NJ, Wong M, Taniguchi C, Petrosino JF, Sastry KJ, Okhuysen PC, Martinez SA, Tan L, Mahmud I, Lorenzi PL, Wargo JA, Klopp AH. Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring. Cancer cell, 2023 Nov 13;41(11):1945-1962.e11. (ICMS-based metabolomics)

32.  Garrett TJ, Coatsworth H*, Mahmud I*, Hamerly T, Stephenson CJ, Ayers JB, Yazd HS, Miller MR, Lednicky JA, Dinglasan RR. A chemical probe into SARS-CoV-2 modulation of host cell lipid metabolism.  Front Microbiol. 2023 Oct 11;14:1251065. doi: 10.3389/fmicb.2023.1251065. eCollection 2023.PMID: 37901834. (*Equally contributed first author). (LCMS-based lipidomics)

33.  Li L, Long J, Mise K, Poungavrin N, Lorenzi PL, Mahmud I, Tan L, Saha PK, Kanwar YS, Chang BH, Danesh FR. The Transcription Factor ChREBP Links Mitochondrial Lipidomes to Mitochondrial Morphology and Progression of Diabetic Kidney Disease. J Biol Chem. 2023 Aug 21:105185. (LCMS-based lipidomics)

34.  Ahmed MSU, Lord BD, Adu Addai B, Singhal SK, Gardner K, Salam AB, Ghebremedhin A, White J, Mahmud I, Martini R, Bedi D, Lin H, Jones JD, Karanam B, Dean-Colomb W, Grizzle W, Wang H, Davis M, Yates CC. Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling. Cancers (Basel). 2023 Apr 13;15(8):2282.

35.  Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer Discovery. 2023 May 4;13(5):1230-1249. (LCMS-based lipidomics)

36.  Katsushima K, Pokhrel R, Mahmud I, Yuan M, Murad R, Baral P, Zhou R, Chapagain P, Garrett T, Stapleton S, Jallo G, Bettegowda C, Raabe E, Wechsler-Reya RJ, Eberhart CG, Perera RJ. The oncogenic circular RNA circ_63706 is a potential therapeutic target in sonic hedgehog-subtype childhood medulloblastomas. Acta Neuropathol Commun. 2023 Mar 10;11(1):38. (LCMS-based metabolomics and lipidomics)

37.  Baek ML, Lee J, Pendleton KE, Berner MJ, Goff EB, Tan L, Martinez SA, Mahmud I, Wang T, Meyer MD, Lim B, Barrish JP, Porter W, Lorenzi PL, Echeverria GV. Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment. Oncogene. 2023 Mar;42(14):1117-1131. (ICMS-based metabolomics)

38.  Li G, Li X, Mahmud I, Ysaguirre J, Fekry B, Wang S, Wei B, Eckel-Mahan KL, Lorenzi PL, Lehner R, Sun K. Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy. JCI Insight. 2023 Jan 24;8(2):e163624. (LCMS-based lipidomics)

39.  Mahmud I*, Lee B*, Pokhrel R, Murad R, Yuan M, Stapleton S, Bettegowda C, Jallo G, Eberhart CG, Garrett T, Perera RJ. Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs. Acta Neuropathologica Communications (2022) 10:25. https://doi.org/10.1186/s40478-022-01326-7. (*Equally contributing first author). (LCMS-based metabolomics and lipidomics)

40.  Mahmud I*, Pinto FG*, Rubio VY, Máquina ADV, Furtado Durans AF, Neto WB, Garrett TJ. Data-Driven Soft Independent Modeling of Class Analogy in Paper Spray Ionization Mass Spectrometry-Based Metabolomics for Rapid Detection of Prostate Cancer. Anal. Chem. 2022, 94, 4, 1925–1931. (*Equally contributing first author). (PSI-MS-based metabolomics)

41.  Vijayakurup V, Maeng K, Lee HS, Meyer B, Burkett S, Nawab A, Dougherty MW, Jobin C, Mahmud I, Garrett TJ, Feely M, Lee KB, Kaye FJ, Guijarro MV, Zajac-Kaye M. Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival. JCI Insight. 2022 Sep 1;e147417.  doi: 10.1172/jci.insight.147417. (LCMS-based metabolomics)

42.  Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, Wojtkowiak JW, Swietach P, Gatenby RA, Bui MM, Merritt ME, McDonald P, Garrett TJ, Gillies RJ. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022 May 10;39(6):110796. doi: 10.1016/j.celrep.2022.110796. (LCMS-based lipidomics and tracing)

43.  Narayan S, Raza A, Mahmud I, Koo N, Garrett TJ, Law ME, Law BK, Sharma AK. Sensitization of FOLFOX/TRAIL-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A. iScience, June (2022). doi: https://doi.org/10.1016/ j.isci.2022.104518.

44.  Stork BA, Dean A, Ortiz AR, Saha P, Putluri N, Planas-Silva MD, Mahmud I, Rajapakshe K, Coarfa C, Knapp S, Lorenzi PL, Kemp BE, Turk BE, Scott JW, Means AR, York B. Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Molecular Metabolism, 62 (2022) 101513. doi.org/10.1016/j.molmet.2022.101513. (ICMS-based metabolomics)

45.  Tan SK, Mahmud I, Fontanesi F, Puchowicz M, Neumann CKA, Griswold AJ, Patel R, Dispagna M, Ahmed HH, Gonzalgo ML, Brown JM, Garrett TJ, Welford SM. Obesity-Dependent Adipokine Chemerin Suppresses Fatty Acid Oxidation to Confer Ferroptosis Resistance (2021). Cancer Discovery, DOI: 10.1158/2159-8290.CD-20-1453. (LCMS-based lipidomics)

46.  Waddell A, Mahmud I, Ding H, Huo Z, Liao D. Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer. Cancers, 13(11):2799 (2021).

47.  Mahmud I, Pinto FG, Rubio VY, Lee B, Pavlovich CP, Perera RJ, Garrett TJ. Rapid Diagnosis of Prostate Cancer Disease Progression Using Paper Spray Ionization Mass Spectrometry. Anal. Chem. 2021, 93, 22, 7774–7780. (PSI-MS-based metabolomics)

48.  Menzies V, Starkweather A, Yao Y, Kelly DL, Garrett TJ, Yang G, Booker S, Swift-Scanlan T, Mahmud I, Lyon DE. Exploring associations between metabolites and symptoms of fatigue, depression, and pain in women with fibromyalgia. Biol Res Nurs. 2021 Jan;23(1):119-126. doi: 10.1177/1099800420941109. PMID: 32677448. (LCMS-based metabolomics)

49.  Mahmud I*, Pinto FG*, Harmon TA, Rubio VY, Garrett TJ. Rapid Prostate Cancer Noninvasive Biomarker Screening Using Segmented Flow Mass Spectrometry-Based Untargeted Metabolomics. Journal of Proteome Research, 2020 19 (5), 2080-2091. (*Equally contributing first author).  (SFMS-based metabolomics)

50.  Lee B, Mahmud I, Marchica J, Dereziński P, Qi F, Wang F, Joshi P, Valerio F, Rivera I, Patel V, Pavlovich CP, Garrett TJ, Schroth GP, Sun Y, Perera RJ. Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery (2019). Scientific Reports, 2020 Feb 28;10(1):3716. (LCMS-based metabolomics)

51.  Mahmud I, Garrett TJ. Mass Spectrometry techniques in Emerging Pathogens Studies: COVID-19 perspectives. J. Am. Soc. Mass Spectrom. September 3, 2020, https://doi.org/10.1021/jasms.0c00238. (Top accessed article of 2020 by Editors of JASMS). (Multiomics)

52.  Lynch Kelly D, Farhadfar N, Starkweather A, Garrett TJ, Yao Y, Wingard JR, Mahmud I, Menzies V, Patel P, Alabasi KM, Lyon D. Global Metabolomics in Allogeneic Hematopoietic Cell Transplant Recipients Discordant for Chronic Graft-versus-Host Disease Biology of Blood and Marrow Transplantation. Biology of Blood and Marrow Transplantation, 2020 Jun 24:S1083-8791(20)30369-4. (LCMS-based metabolomics)

53.  Mahmud I, Kabir M, Haque R, Garrett TJ. Decoding the Metabolome and Lipidome of Child Malnutrition by Mass Spectrometric techniques: Present Status and Future perspectives. Analytical chemistry, 91(23):14784-14791 (2019). 

54.  Mahmud I, Liao D. DAXX in cancer: phenomena, processes, mechanisms, and regulation. Nucleic Acids Res. 47, 7734–7752 (2019). 

55.  Masannat J, Purayil HT, Zhang Y, Russin M, Mahmud I, Kim W, Liao D, Daaka Y. βArrestin2 Mediates Renal Cell Carcinoma Tumor Growth. Scientific Reports, 8(1):4879.

56.  Mahmud I, Sandi Sternberg, Michael Williams, Timothy J Garrett (2017). Comparison of Global Metabolites Extraction strategies for Soybeans using UHPLC-HRMS. Analytical and Bioanalytical Chemistry, 409(26), 6173-6180. (LCMS-based metabolomics)

57.  Noorali S., Altidor K.R., Emelife S., Mahmud I, White R.S., Harris R.H. Human MicroRNA-602 Inhibits Hepatitis C Virus Genotype 1b Infection and Promotes Tumor Suppressor Gene Expression in a Hepatoma Cell Line (2017). J Virol Antivir Res 2016, 5(2): 1-10.

58.  Mahmud I and Daiqing Liao (2015). Microarray gene expression profiling reveals potential mechanisms of tumor suppression by the class I HDAC-selective benzoylhydrazide inhibitors. Genomics Data 5, 257-259.

59.  Mahmud I, Kousik C, Hassell R, Chowdhury K, Boroujerdi A. NMR Spectroscopy Identifies Metabolites Translocated from Powdery Mildew Resistant Rootstocks to Susceptible Watermelon Scions. Journal of agricultural and food chemistry, 63 (36), 8083–8091 (2015). (NMR-based metabolomics)

60.  Mahmud I, Chowdhury K, Shrestha B, Boroujerdi A. NMR-based Metabolomics Profile Comparison to Distinguish between Embryogenic and Non-Embryogenic Callus Tissue of Sugarcane at the Biochemical Level. In vitro cellular and developmental biology–Plant, 51(3), 340-349 (2015). (NMR-based metabolomics)

61.  Mahmud I, Thapaliya M, Boroujerdi A, Chowdhury K. NMR-based metabolomics study of the biochemical relationship between sugarcane callus tissues and their respective nutrient culture media. Anal and Bioanal Chem, 406 (24), 5997-6005 (2014). (NMR-based metabolomics)

62.  Mahmud I, Chowdhury K, Boroujerdi A. Tissue-Specific Metabolic Profile Study of Moringa oleifera L. Using Nuclear Magnetic Resonance Spectroscopy. Plant Tissue Cult. & Biotech. 24 (1), 77-86 (2014). (NMR-based metabolomics)

63.  Minak J, Kabir M, Mahmud I, Liu Y, Liu L, Haque R, Petri WA. Evaluation of rapid antigen point-of care tests for detection of Giardia and Cryptosporidium species in human fecal specimens. Journal of clinical microbiology, 50 (1), 154-156 (2012).