Dr. Ke's research centers around promoting meaningful science teaching and learning through disciplinary practices like modeling, particularly in the context of complex societal issues. Issues like pandemics and climate change provide compelling reasons for students to learn science and engage in disciplinary practices. This focus also supports students in exploring how science can be used to inform societal solutions and personal decision-making. Dr. Ke explores meaningful science teaching and learning through three interconnected dimensions: curriculum development, student learning, and teacher professional development. His work recognizes both students and teachers as active epistemic agents in building their own knowledge to make sense of the world. In 2026, he was recognized for his research contributions as a recipient of NARST’s Early Career Research Award.