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Saurabh D Bhandare
Ph.D (Honoris Causa)
Doctrin de Philosophy Award
is
The Pride of India
Recipients of Honorary PhD are recognized as Resource person of international repute in Community Development, Education and Management
Mission of Honorary PhD is to produce Technologists of calibre by imparting quality Education to the students
Mission of Honorary PhD is to promote research and extension among Universities and other research organizations in all aspects of research, extension and training.
Mission of Honorary PhD is to undertake consultancies and studies in Community Development, Education and Management
Mission of Honorary PhD is to provide advisory services in Community Development, Education and Management
Exclusive Interview with Saurabh D Bhandare
Ph.D (Honoris Causa)
Question: What inspired you to enter into Pharmaceutics?
1. Answer: Pharmaceutics is a broad subject of study in pharmacy that offers a lot of opportunities for research.
In a nutshell, pharmaceutics is the study of the preparation, usage, and sale of therapeutic medications in formulation.
API, a chemical synthetic medication of pharmacological value, is a newer natural medicine.
This also involves research and development in the realm of novel chemical entities (NCEs) that are both safe and effective in drug use.
As a result of its vast scope in the realm of pharmaceutics, it can be described as the science of dosage form design, which involves the formulation of a pure pharmacological component into a dosage form.
It can be described as the science of dosage form design, which involves the formulation of a pure pharmacological component into a dosage form, due to its broad reach in the field of pharmaceutics.
The main source of inspiration in choosing pharmaceutics is the idea behind the establishment of the study of quantitative aspects of drug administration, which involves the design, development, and assessment of drugs in combination with an appropriate dosage form.
Pharmaceutics is the best therapy for human or mankind healing today.
To treat and cure the condition, ordinary pharmaceutics reaches the patient directly via appropriate and pleasant formulations. As a result, the broad breadth of treating and curing disease in both humans and animals has drawn attention to the creation of a healthy-driven culture that values healthy life and healthy living.
Question:Since how long, you been into this scientific field and in which cities you have been associated for administration, entrepreneurship, teaching, research, commercial and training programs?
Answer:
I've spent the last 4.5 years working in the scientific field. Working in majour cities such as:Bombay and, Nashik along with some villages associated to Nasik city in its remote rural areas.
Question:What are your future plans for administration, entrepreneurship, teaching, research and training programs in Pharmaceutics?
Answer:
It's rewarding to have worked in the field of pharmaceutics as part of a research training programme, teaching, along with other value-added fields.
Question:What kind of businesses can be started in Pharmaceutics? What minimum infrastructure would it need?
Answer:
Owing to a newer improve dosage delivery, type of formulations that can be developed including a great scope of business and as per the customer requirements. This improved dosage forms can be conventional and, also would help patient convenience in administration of dosage.
The minimum requirement of infrastructure at least of a chemical and, Pharmaceutical Laboratories that in compliance with cGMP guideline as well as other important guidelines that are required for preparation of dosage forms such as: USFDA, MHRA, etc.; along with the pharmacopoeias.
Question: What are your recommendations to improve the standards of journals publishing research articles on Pharmaceutics?
Answer:
Journals are already capacitors in Publication or publishing research work of novel standards as well review articles in the journal. Therefore, I must be recommending articles that include good life improving research in the field of pharmaceutics.
Question: What are your recommendations to improve syllabus of Pharmaceutics for more creativity, applications and opportunities?
Answer:
My recommendation would be to choose a syllabus that includes basic ideas as well standard concepts that includes industrial training guidelines and subjective information on new approaches in pharmaceutics which must include NDDS, TDDS, along with some expert’s solutions that would benefit and maintain the interest of students and, entrepreneurs in the field of pharmaceutics. Eliminating older concepts, outmoded notions and outdated knowledge or Technology is a must requirement and of great interest in today's era to improve in the field of Technology can acquire modernisation.
Question: What is Pharmaceutics? What are the major branches in Pharmaceutics?
Answer:
Pharmaceutics is the branch of scientific study that is concerned with the preparation use or sale of medicinal drugs either over the counter or on prescription.
pharmaceutics is the branch of pharmacy which includes the study of formulation of a drug into a dosage form. it is a systematic approach to get and effective and, stable formulation considering all aspects required to maintain its quality. it also deals with technology involved in large scale manufacturing of these dosage forms. it is the responsibility of manufacturing chemist to formulate a dosage form which is uniform, effective, stable, and, safe along with the information about its storage, use, precautions to be taken while it is administered and associated side effects. Thus, pharmaceutics is a branch which imparts the knowledge required out all these responsibilities to formulate a suitable and standard dosage form as needed or required.
Dosage form which are commonly dispensed in retail or Hospital pharmacy are tablets, sachets, mouthwashes, gargles, capsules, solutions, suspensions, emulsions, aerosols, aromatic water, dentifrices, ear drops, eye drops, enemas, nasal drops, cones, throat paints, gels, implants, innovations in inhalers, injections, jellies, linctuses, pessaries, spirit, tinctures, suppositories, glycerines, granules, elixirs, syrups, dry syrup, ointments, lotions, liniments, dusting powders, etc.
These all are included in pharmaceutics.
Dosage forms: depending upon the sterility, dosage forms can be classified as:
Sterile dosage forms and, non-sterile dosage forms.
1.Sterile dosage forms:
a. Parenteral dosage forms:
i. small volume parenterals.
ii. large volume parenterals.
b. Ophthalmic dosage forms:
i. eye drops.
ii. eye lotions.
iii. eye ointment.
iv. Ocuserts.
C. Implants:
i. transdermal implants.
ii. dental implants: Endosteal.
iii. Vascular stents: improve and preserve blood flow.
iv. electro stimulation devices that regulate heart rhythms.
v. Orthopaedic devices: restore range of motion of hips, knees and, reinforce spine.
vi. intrathecal pump: used in delivery of hormones.
example: Histrelin implants for the palliative treatment of prostate cancer and, uterine fibroids along with induced early puberty in children. (Supprelin), Levonorgestrel (Jadelle) and, estonogestrel (Implanon).
Other solid implants: found in ophthalmology for treatment of macular edema and, retinal vein occlusion using corticosteroids (Osurdex), with the products in the treatment of glaucoma (prostaglandins) and, age-related macular degeneration.
subcutaneous implants and, also Novel Drug Delivery forms such as: intrauterine devices (IUDs), and, intravaginal rings (IVRs).
FDA approved a levonorgestel eluting IUD, (Mirena), providing contraception for up to 5 years of its first use.
Non sterile dosage forms:
a. Solid dosage forms:
Powders:
a. Internal, b. External.
2 .Compressed forms of tablets. (all types of tablets).
3 .Non-compressor types:
i. Pills, ii. Capsules, iii. Sachets.
Semi-solid dosage forms:
a. Ointments,
b. Creams,
c. Pastes,
d. Jellies,
e. Poultices,
f. Plasters.
Liquid dosage forms:
a. Monobasic,
b. Biphasic.
Gaseous dosage forms:
a. Aerosols,
b. Inhalants.
Comments on requirements for drug delivery:
along with implantable devices, main materials, considerations for use in drug delivery include biocompatibility, stability and, durability (except in the case of biodegradable drug delivery systems), and, the ability of the material to control release of the active pharmaceutical ingredient. (API).
API, Matrix.
Ethyl vinyl acetate, (EVA).
biodegradable material such as: poly(Lactic-co-glycolic acid) or, PLGA to controllable released to drugs.
site specific, control release of therapeutic agents.
Branches of pharmaceutics include:
Pharmacokinetics,
Pharmacodynamics,
Pharmacoepidemiology,
Pharmacogenomics,
Pharmacovigilance,
Pharmaceutical formulations,
Pharmaceutical Technology,
Pharmaceutical manufacturing,
Dispensing pharmacy,
Physical pharmacy.
Pharmaceutics can be clearly understood as:
pharmaceutics is the discipline of Pharmacy that deals with all facets of process after learning a new chemical entity (NCE) or an API into a medication able to be safely and, effectively used by patience in the community. Pharmaceutics is the science of designing dosage form of therapeutic importance.
Question: What are your recommendations to frame guidelines on funding of research projects on Pharmaceutics?
Answer:
To meet any research standards, the research endeavour must be sufficiently supported. The funding for the search must be unbiased and adequately justified till the project is completed.
Funding could also include company-sponsored, non-partisan government grants in favour of creative research improvements and tactics, as well as assistance to research graduates in terms of financial support and strength during their studies.
Question: How can universities produce revolutionary PhD and Post Doc thesis and dissertations on Pharmaceutics? What are your recommendations to improve the academic standards?
Answer:
- Universities can accept a large number of PhD and postdoctoral students who are really engaged and devoted to learning and growing their interest in the development of a certain subject area.In addition, the university must take steps to address educational issues such as demotivation in a particular candidate.
Question: What are your views on Exploration of Natural Polymer Isolated from ‘Manihot Esculenta’ with an Approach to Study Its Patch Forming Ability?
Answer:
The polymer can be made into thin film. Thin layer wafers with API loaded in it for the formulations used in oral, vaginal, rectal and, as well topical route of drug delivery.
Question: How can students seek job and career opportunities in Pharmaceutics?
Answer:Student can use different job portals and, placement services to seek job and, career opportunities in the field of pharmaceutics.
Question: What job titles are available in Pharmaceutics?
Answer:Research and development, formulation and development, medical assistant, pharmacist, Pharma marketing, medical representative, product supervisor.
Question: Which are Typical employers in Pharmaceutics?
Answer
Pharmacy Companies, pharmacy industries involved in manufacture and, research and development of a product.
Question: Which are the courses available in Pharmaceutics?
Answer
Courses available in pharmaceutics.
1.Aadvanced pharmaceutics,
2.Advanced Drug Delivery System,
3.Method of national drug delivery,
4.Methods of Novel Drug Delivery,
5.Essentials in development of pharmaceutics,
6.Pharmaceutical dispensing practices in pharmacy,
7.Advanced Pharmaceutical techniques.
Question: Please provide comprehensive list of journals in Pharmaceutics?
Answer
International Journal of pharmaceutics,
Journal of Pharmaceutical Sciences,
European journal of pharmaceutics and biopharmaceutics,
Pharmaceutical research,
The pharmaceutical journal,
Molecular pharmaceutics,
Drug testing and analysis.
Question: What are your recommendations to write a world class research article in Pharmaceutics? What essential components and factors must be there?
Answer
To write a world-class research article in pharmaceutics one must consider the aspect and, development factors that are advantageous in development of novel and modified drug delivery to enhance the therapy ratio or increase therapy profile of a drug or API.
Question: What are your recommendations to write a world class case report in Pharmaceutics? What essential components and factors must be there?
Answer
Studying the case and, analysing it with different parameters is a majour concern along with studying the case and analysing it using various metrics.
Different parameters that include the development in terms of drug delivery, formulation development and, modified formulations.
Development in terms of medication delivery, formulation development, and changed formulations are among the several factors.
Question: What are your recommendations to write a world class review in Pharmaceutics? What essential components and factors must be there?
Answer
To write a better review in pharmaceutics one must consider information from good quality research articles and, cite adequate literature displaying quality information on recent topics that haven't been justified.
Question: What are your recommendations to establish a world class research institute for Pharmaceutics?
Answer
Must be well equipped Laboratories and facility that meet the requirement for pharmaceutical development as per cGMP guidelines and, ICH requirements, ICH regulations for pharmaceutical development.
Question: What are your recommendations to improve employment and scope in Pharmaceutics?
Answer:
To advance and improve employment in pharmaceutics one must be involved in developing companies, pharmaceutical enterprises and industries that are involved in pharmaceutical preparation.
Question: Would you start a campaign to request government to offer free of cost internet to all people of your country as fundamental right, because it plays a significant role in education, awareness, implementation of government policies and economic development of country
Answer:
No.
Question: What are your recommendations to authors, who are writing Books on Pharmaceutics for more creativity and understanding of the subject?
Answer:
Authors can use great source of tool to improve and deliver excellence in pharmaceutics for is better understanding.
Question: What according to you are the Top 5 major challenges (research problems) which need to be resolved urgently by world’s scientists in the area of Pharmaceutics?
Answer:
Development and formulation stability,
Development in drug compatible excipients,
3.Development in study and prevention of polymorphism,
4.Overcome challenges in drug delivery such as:
i.Osmotic pump,
ii. Nanoparticles,
iii. Liposomes,
iv. Ocuserts.
5. Include more development in modified drug delivery that includes elimination from first pass effect of drugs; for drugs that undergo changes in hepatic transformation.
Question: What are your recommendations to improve standards of Conferences in Pharmaceutics? How can they be brainstorming and more creative?
Answer:
However, one cannot have control on how the conference must go but while choosing; select right person and, attend their conference is the only way to be more improved and, creative.
Most brainstorming and creative presentations or conferences come from better learned people automatically and, does not required to be justified.
Question: Which major challenges do you see to establish India as world leader in Pharmaceutics?
Answer:In such there are no challenges.
Question: Any other thing, you would like to share with World?
Answer:
It's a happy living world and, we must not hate but seek the peace!
Saurabh D. Bhandare
WORK EXPERIENCE:
Current work assistance professor at Dr. U.R.M. college of B. pharmacy.
2) R. oxygen manufacturing unit as quality control and Laboratory In charge. 2019-2021 2).
At 1) Quintiles Research–Two years- ‘Regulatory and start up, Documents Review’. (GDN). As Clinical Process Associate-I. (Regulatory Submission, CTMS Operation). 2016-2018. (Document review, customization and preparation, Submission and Approval Tracking, Regulatory Submission-EC, RA. For EU region. e-TMF mailbox handling, TMF, CTA submissions, work over multiple IT systems for filing documents, tracking and repositories). (Onshore and off shore management). The detailed work profile includes: working on regulatory documents, regulatory submissions in CTMS, Document customization, review, work on repositories. Central Management for TMF. Manage and resolve queries with team members both onshore and offshore management. Checking with the team members and maintaining issue logs and FAQs. Checking with the quality of documents, maintain document, document filing details and document numbers in the excel and onsite reporting and weekly and daily maintenance of study systems onsite monitoring. Maintain study log along with CTMS tracking. Also, submission to regulatory boards, IRB submissions and EC submission. Review Investigator Brochures and Patient Materials along with regulatory submissions to the EU. and US. Maintain and update site information such as contact and account management. Review PI, SN, Investigator. Maintain and update study logs along with reports submission. Maintain e-TMF and submission on TMF, Elvis filing and submission. General guidance preparation on document identification and filing in the systems. Also maintain and redirect the available faults and reports. Maintain check on study profile to site management. Elvis contract upload. Maintain R.date, D.Date, F.E.Date. Task management and request approval. Generate Ticket and maintain ticket numbers for the assigned study completion. Customization S.V.L. Submission approval tracking for the EU and US. And ROW. Identify and execute type of submission. EDP Data entry. Check on daily updates on SOP’s and acknowledge SOP’s. Check on status of protocol and update, P.A., F.D.F. check on update to ISF, SRM, and Maintain minutes of meetings.
PUBLICATION:
Saurabh et al, “Natural Polymers: As Pharmaceutical Excipient and Their Application in Different Pharmaceutical Formulations – A Review.” World Journal of Pharmaceutical Research. Volume-4, Issue - 6, PP. 626-644.
CONFERENCE:
National Conference: Attended –01 time.
ACADEMIC QUALIFICATION:
Qualification Year of Completion University/Board Class/Grade
SSC 2007 Pune, Div.B.-Nashik. Grade B
HSC 2009 Pune, Div.B.-Nashik. Grade B
B. Pharmacy 2013 Pune. Higher Second Class
M. Pharmacy 2015 SPPU, Pune. Grade A
ADDITIONAL QUALIFICATION:
English Type writing (speed 30 W.P.M). M.S. CIT.
RESEARCH WORK:
B. Pharmacy: Herbal Cosmetics
M. Pharmacy:
Exploration of Natural Polymer Isolated from ‘Manihot Esculenta’ with an Approach to Study Its Patch Forming Ability.
COMPUTER LITERACY:
Practical Knowledge of Computer. MS office.
LANGUAGE OF COMMUNICATION:
English.
AREA OF INTEREST:
Teaching and Lecturer-ship, Pharmaceutics, Clinical Research, Pharmacovigilance, Regulatory, Research and Development, Lectureship or Teaching Assistant, Central Monitor.
SKILL SETS:
Regulatory filing and submissions, ICH-GCP, PDF tools and tool boxes, deck preparations and presentations, preparation of study materials, IPQC, CTMS operations, GDP, GxP, GLP, GCP, and GMP.
HOBBIES:
Play Violin, Listen to Music, Sing and Paint.
AWARDS:
I) Secure 1st position in English essay writing competition in N.P.W. by Indian Pharmaceutical Association. II) Secure 1st position in Techno-fest ‘Innovators Conner’-MET BKC.
ATTRIBUTE:
1. Cognitive and positive attitude towards Work. 2. Team work, accept and resolve challenges. 3. Having great personality and self-motivated.
PERSONAL INFORMATION:
1. Name: Mr. Saurabh D. Bhandare. 2. Father’s Name: Mr. D.R. Bhandare. 3. Mother’s Name: Ms. V.D. Bhandare. 4. D.O.B.:29-12-1991. 5. Sex: male
PARTICIPATION AND CERTIFICATIONS: NSS. Meteroite14. United Nations World Space Week (KYF) Relocation Details: i) Ready to Relocate. ii) Location: Nasik/Bombay.
Recent knowledge and certificate of achievements:
1. Corona virus facts: testing your pandemic knowledge.
2. FDA certification in leveraging health literacy and patient preferences.
3. Drug development process. 4. Epidemiology.
Papers published:
Review articles:
Bhandare, S., Kavade, E., Surse, S., 2015. NATURAL POLYMERS: AS PHARMACEUTICAL EXCIPIENTS AND THEIR APPLICATIONS IN DIFFERENT PHARMACEUTICAL FORMULATIONS - A REVIEW. World Journal of Pharmaceutical Research., 4(6), pp.626-644.
Bhandare, S., 2019. REGULATORY REQUIREMENTS AND REGULATORY OPERATIONS IN PHARMACEUTICALS. World Journal of Pharmaceutical Researc., 8(9), pp.418-428.
Bhandare, S., 2019. CLINICAL DEVELOPMENT AND THE DEVELOPMENT PROCESS INVOLVED IN BRINGING NEW MEDICINES TO THE MARKET. World Journal of Pharmaceutical Research., 9(1), pp.810-825.
Bhandare, S., 2020. SCIENTIFIC COMMUNICATION ON COVID-19 AS: A DISEASE CAUSING AGENT AND A GLOBAL CAUSE OF PANDEMIC. World Journal of Pharmaceutical Research., 9(6), pp.2065-2098.
Bhandare, S., 2020. REPORT ON THE STUDY OF NOVEL APPROACHES, TECHNICAL CONSIDERATION AND SUPPORT IN THE TREATMENT THERAPY AND PANDEMIC INFECTION PREPAREDNESS FOR THE RECENT EPIDEMIC OUTBREAK OF SARS-CoV2 INFECTION, COVID-19 DISEASE AND PANDEMIC MANAGEMENT INCLUDING CLINICAL TRIALS SOLUTIONS AND REQUIRED DOCUMENTATION PROCEDURES. World Journal of Pharmaceutical Research., 9(8), pp.991-1031.
Research work.
Bhandare, S., Deokar, G.S., 2021. EVALUATION AND CHARACTERISATION OF A NOVEL POLYMER AS A PHARMACEUTICAL EXCIPIENT OBTAINED AS ME-C.P A MODIFIED POLYMER. World Journal of Pharmaceutical Research., 11(1), pp.817-845.
Bhandare, S., 2021. PHARMACOGNOSTIC STANDARDISATION OF PARTS OF THE WHOLE PLANT OF THE Manihot Esculenta, Crantz (L) AND ITS CHARACTERISTIC EVALUATION AND CONDUCT OF STUDY FOR ITS IDENTIFICATION. World Journal of Pharmaceutical Research., 10(5), pp.1419-1447.
Bhandare, S., 2022. TO STUDY THE FORMULATION ABILITY OF NEW POLYMER SOURCE OBTAINED FROM AEGLE MARMELOS FOR ITS FILM FORMING GEL USING AN ANTIFUNGAL AGENT-CLOTRIMAZOLE. World Journal of Pharmaceutical Research, [online] 11(4), pp.988-1013. Available at:
Case Study:
Bhandare, S., 2021. REMDESIVIER; CLINICAL SIGNIFICANCE, IMPLICATIONS, CHEMISTRY AND, MEDICINAL SYNTHESIS. World Journal of Pharmaceutical Research., 10(12), pp.1143-1175.