Resources

Repositories for biomaterials

We value open and accessible science. When our lab develops tools that we expect to be useful for the community, we provide these through repositories.

• Plasmids are available from Addgene

• Various C. difficile strains, including control strains for antimicrobial susceptibility testing, are available through NCTC

• A collection of R. gnavus strains for which we have generated complete genomes is available from DSMZ

If researchers are interested in published strains or constructs that are not (yet) available through these resources, we encourage them to reach out to us.

Repositories for digital data

If our studies involve omics data that is suitable for reanalysis, we strive to make these available via dedicated repositories. The relevant accessions are listed in our publications.

• Short and long read sequencing data is made available through ENA or SRA

• Proteomics data is accessible through PRIDE

• Structures are deposited in PDB

Dutch National Expertise Center for C. difficile infections

The LUMC hosts the Dutch National Expertise Center for C. difficile infections in collaboration with the  Centre for Infectious Disease Control of the National Institute for Public Health and the Environment (RIVM). We perform surveillance and ad hoc typing for national and international partners.  For this, we use a well-characterized collection of reference isolates. 

Currently, we perform both capillary electrophoresis PCR ribotyping, as well as whole genome-based typing.

If you have a question that can benefit from our expertise, do not hesitate to reach out.

• Patiëntenfolder Clostridioides difficile infectie (LUMC)

• European Centre for Disease Prevention and Control Clostridioides difficile infections