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One of our research lines in this topic focuses on deciphering how the Hippo-YAP1 signaling pathway regulates chromatin structure to orchestrate cell-fate decisions in hESCs and gastrulating epiblast.
Active Funding: NIH R01 (NICHD)
Image from Stronati et al. 2022 shows that YAP deletion alters the formation of the three germinal layers in the micropatterned 2D gastruloids.
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