Recent publications
YAP1 and QSER1 are key modulators of embryonic signaling pathways in the mammalian epiblast.
Abraham E, Roule T, Douglas A, Megill E, Pericak OM, Howe JE, Choya-Foces C, Garbincius JF, Cohen HM, Roig-Flórez P, Zubillaga M, Andrake MD, Kim S, Elrod JW, Akizu N, Estaras C. EMBO Rep. 2026
A retinoic acid:YAP1 signaling axis controls atrial lineage commitment.
Abraham E, Kostina A, Volmert B, Roule T, Huang L, Yu J, Williams AE, Megill E, Douglas A, Pericak OM, Morris A, Stronati E, Larrinaga-Zamanillo A, Fueyo R, Zubillaga M, Andrake MD, Akizu N, Aguirre A, Estaras C. Cell Rep. 2025
Single-Cell RNA Sequencing of Mutant Whole Mouse Embryos: From the Epiblast to the End of Gastrulation.
Elizabeth Abraham, Mikel Zubillaga, Thomas Roule, Eleonora Stronati, Naiara Akizu, Estaras C, Journal of Visualized Experiments (JoVe), 2024.
YAP regulates the self-organized fate patterning of hESC-derived gastruloids.
Stronati E, Giraldez S,Huang L, Abraham E, McGuire GR, Hsu HT, Jones KA, Estaras C.
Stem Cell Reports, 2022 Feb https://doi.org/10.1016/j.stemcr.2021.12.012
Specifying the Anterior Primitive Streak by Modulating YAP1 Levels in Human Pluripotent Stem Cells.
Hsu HT, Estarás C, Huang L, Jones KA.
Stem Cell Reports. 2018 Dec 11;11(6):1357-1364. doi: 10.1016/j.stemcr.2018.10.013. Epub 2018 Nov 15.
Fueyo R, Iacobucci S, Pappa S, Estarás C, Lois S, Vicioso-Mantis M, Navarro C, Cruz-Molina S, Reyes JC, Rada-Iglesias Á, de la Cruz X, Martínez-Balbás MA.
Nucleic Acids Res. 2018 Apr 20;46(7):3351-3365. doi: 10.1093/nar/gky093.
YAP repression of the WNT3 gene controls hESC differentiation along the cardiac mesoderm lineage.
Estarás C, Hsu HT, Huang L, Jones KA.
Genes Dev. 2017 Nov 15;31(22):2250-2263. doi: 10.1101/gad.307512.117. Epub 2017 Dec 21.
EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21.
Akizu N, García MA, Estarás C, Fueyo R, Badosa C, de la Cruz X, Martínez-Balbás MA.
Open Biol. 2016 Apr;6(4):150227. doi: 10.1098/rsob.150227. Epub 2016 Apr 20.
Estarás C, Benner C, Jones KA.
Mol Cell. 2015 Jun 4;58(5):780-93. doi: 10.1016/j.molcel.2015.04.001. Epub 2015 Apr 30