Image titled Virus from Innovative Genomic Institute
Viruses evolve when two viruses infect a cell at the same time. In this manner, viruses are able to swap genetic material in order to create new variants of a virus (which consist of different properties). This evolutionary process of virus mutation and replication can be quite dangerous for the infected host. One method of managing viruses and virus mutations is through the creation and utilization of vaccines. According to the CDC, Vaccines build immunity by imitating an infection. The infection used in vaccines is extremely unlikely to cause illness, but it prompts the immune system to produce T-lymphocytes and antibodies. (CDC, 2018). Vaccines have shown to be one of the most groundbreaking scientific discoveries and implementations of modern medicine. However, virus mutations can challenge the efficacy of vaccinations. To track the evolution of the virus, scientists study mutation rates. Mutation rates depict “the probability that a change in genetic information is passed on to the next generation” (Weaver, 2016). For example, through the study of mutation rates, it was found that those infected with HIV-1 experience drug resistance daily, so multiple drugs are necessary to manage the infection (Weaver, 2016). Studying these mutation rates is vital to effectively predicting the evolution of the virus and therefore, knowing which vaccinations or medications best combat the infection.
Image titled COVID-19 Vaccine by Alachua County on Flickr.com
Image titled Moderna Booster Shot - COVID-19 Vaccination by Anthony Quintano on Flickr.com
Some viruses, like SARS-CoV-2 can mutate very quickly, as we have seen during the pandemic - the virus has actually mutated several times within the course of a single year! This not only exemplifies how viruses demonstrate evolution, but it also shows how pandemics, such as COVID-19, can be extraordinarily difficult to end. Viruses are able to mutate their own genetic code, making many vaccines ineffective, as vaccines function based on a prediction of a virus’s genetic sequence. Throughout the years of 2020 and 2021, many vaccinations were found to become ineffective shortly after implementation as a result of the coronavirus’s ability to mutate. According to a Today news article, there were several different COVID-19 variants which had been discovered. More specifically, variants of the virus known as SARS-CoV-2 have emerged from the U.S. to the U.K. to South Africa and Brazil. As shown by this pandemic, a virus displays a remarkable ability to evolve quicker than humans could ever imagine. Their ability to evolve quicker than vaccines are produced allow them to continue to harm populations of individuals. As these viruses mutate and evolve, scientists are discovering more methods of protecting the public. As of 2021, the Food and Drug Administration has authorized the use of the Pfizer, Moderna, and Johnson and Johnson booster shots for the coronavirus. Booster shots are defined as “an additional dose of a vaccine given after the protection provided by the original shot(s) has begun to decrease over time” (Magakris & Kelen, 2021). These booster shots can reinforce the efficacy of the original vaccination, supporting the end of the pandemic.
References
Magakris, L., & Kelen, G. (2021). Booster Shots and Third Doses for COVID-19 Vaccines: What You Need to Know. Johns Hopkins Medicine. Booster Shots and Third Doses for COVID-19 Vaccines: What You Need to Know
Should I be concerned about COVID-19 variants? Experts break it down. (2021, January 28). TODAY. Retrieved from https://www.today.com/health/how-many-strains-covid-19-t207173
Singh, J. (2021). Evolutionary trajectory of SARS-CoV-2 and emerging variants. Virology Journal, 1-22. https://rwulib.idm.oclc.org/loginurl=https://search.ebscohost.com/login.aspx direct=true&db=a9h&AN=151933573&site=ehost-live
Weaver Scott, C. (2016). Virus evolution : current research and future directions. Caister Academic Press.